Journal of Medical Internet Research - International Scientific Journal for Medical Research, Information and Communication on the Internet #Preprint #PeerReviewMe: Warning: This is a unreviewed preprint. Readers are warned that the document has not been peer-reviewed by expert/patient reviewers or an academic editor, may contain misleading claims, and is likely to undergo changes before final publication, if accepted, or may have been rejected/withdrawn. Readers with interest and expertise are encouraged to sign up as peer-reviewer, if the paper is within an open peer-review period. Please cite this preprint only for review purposes or for grant applications and CVs (if you are the author). Background: Given the fact of an aging society, new supply measures and living concepts are needed, especially as health impairments along with care dependency increase with age. As many elderly people wish to stay at home for as long as possible, ambient assisted living (AAL) represents a support for aging in place. Objective: AAL combines medical and care technology within living environments and is therefore a promising approach to cope with demographic change in terms of fast-growing care needs and fewer skilled workers. Ultrasonic whistles represent one innovative technical possibility for such supportive housing solutions. Central fields of application are home automation, emergency service, and positioning. As AAL technologies affect sensitive areas of life, it is of great interest under which conditions they are accepted or rejected taking individual user requirements into account. Methods: In this study, we examined the acceptance of ultrasonic whistles in home care by function and room using an online questionnaire. Besides an evaluation of the overall usefulness, we focused on the intention to use ultrasonic whistles, n = 270 participants assessed home automation, emergency service, and positioning as specific functions of ultrasonic whistles. Further, bathroom, bedroom, and living room were evaluated as specific usage locations (rooms). With regard to the user’s perspective, the focus was set on age and attitudes towards aging of care receivers. Results: The study revealed a significant influence of function (F(1.967,529.167) = 60.444; P < .001), room (F(1.731,465.739) = 41.388; P < .001), and the interaction of function and room (F(3.051,831.303) = 8.701; P < .001) on the acceptance of ultrasonic whistles: the use of emergency services within the bathroom represented the most accepted alternative, whereas positioning within the living room received the comparably lowest evaluations. While user diversity played overall a minor role for acceptance, the assessment of single applications differed among user groups, particularly with regard to age differences (F(20,500) = 1.988; P = .007 < .01) in the evaluation of specific installation options, such as automated doors. Conclusions: The study revealed profound insights into the user-centered assessment of ultrasonic whistles in home care and discovered function and room as influencing acceptance parameters. Concerning user characteristics, age and attitude towards aging partly affected these evaluations forming the basis for and showing the importance of further investigations in this context. Clinical Trial: Does not apply