The use of the KTP 532 nm vascular laser in the treatment of erythema and telangiectasia caused by low temperature exposure - case report. A case report. The paper presents a case of effective treatment of frostbite vascular lesions in the face with the use of a 532nm KTP laser in a 55-year-old man with a long history of skin exposure to low temperatures. Aim. The aim of this study is to draw attention to the possibility of using laser therapy in the treatment of skin disorders that are a complication of exposure to low temperatures. In the article below, we present the reduction of vascular lesions of the facial skin during a series of laser treatments with the use of the 532nm laser, meeting the growing interest of patients and doctors in the use of laser therapy in the treatment of skin vascular lesions. Conclusions. The use of laser therapy with the KTP 532nm laser can be an important and effective element in the treatment of skin vascular lesions.

Introduction and purpose Due to the growing tendency to diagnose obesity in patients, scientists are trying to find drugs that facilitate weight reduction. An example of such a formulation is the GLP-1 analogue semaglutide. The following article is an analysis of the current knowledge on the effectiveness and safety of obesity treatment with semaglutide based on available publications in Pubmed and Google Scholar databases. State of knowledge The main mechanism of semaglutide is based on a stimulation of insulin secretion from pancreatic beta cells, and inhibition of glucagon from alpha cells, inhibition of hepatic gluconeogenesis, and reduction of energy consumption with minimal impact on energy expenditure. In clinical trials, it showed the best results compared to placebo and other drugs used in weight reduction. Participants treated with semaglutide achieved a reduction in waist circumference, improvements in blood pressure parameters, HbA1c levels, total cholesterol, LDL cholesterol, triglycerides, and CRP protein, and increased HDL cholesterol levels. Semaglutide is well tolerated by patients, and its main side effects come from the gastrointestinal tract, including nausea, emesis, diarrhea. Summary The analysis of the latest publications and meta-analyzes of the literature shows that the use of semaglutide is safe and effective in the treatment of obesity. The positive effect of semaglutide on weight reduction also contributes to the reduction of the risk of cardiovascular events and other obesity-related complications. It is also well tolerated by patients, which translates into possible longer use, and weekly subcutaneous injections are not burdensome for patients. Key words: semaglutide; obesity; GLP-1 analogue; overweight

Acne inverse sometimes known as hidradenitis suppurativa is a long-term dermatological condition. Due to the poorly examined nature of the disease the effectiveness of its treatments is unclear. More than 50 interventions have been described and therefore its diagnostic and the treatment can be challenging. The aim of this case report is to draw attention to the possible use of laser therapy in the treatment of hidradenitis suppurativa. A case report. We report the case of 27-year-old woman that has been successfully treated with laser after years of an ineffective treatment. Due to the failure of systemic and local antibiotic therapy, hormone therapy, surgical drainage and orally and externally applied retinoids, removal of lesions using a CO2 laser knife and a fractional laser therapy combining a CO2 laser and a 1570 nm wavelength laser on the surface of the affected skin was performed. Conclusions. The use of laser therapy, with particular emphasis on the CO2 laser, may be an important and effective element of hidradenitis suppurativa treatment.

Background/Objectives: Basal cell carcinoma (BCC) is the most common form of skin cancer, typically exhibiting slow growth and limited metastatic potential. However, in rare, long-standing cases, particularly in high-risk facial regions, deep infiltration into structures such as bone may occur. This study aimed to evaluate whether BCC with bone involvement remains a relevant clinical issue, based on three decades of clinical experience, supplemented by a review of the existing literature. Methods: Medical records of patients treated for facial BCC between 1994 and 2025 at a dermatologic surgery department in Lower Silesia were retrospectively reviewed. Among more than 10,000 cases, eight instances of histologically confirmed bone invasion were identified. Clinical and surgical parameters were analyzed, including patient age, tumor size and location, prior treatment and reconstruction method. Relevant literature was incorporated to provide broader clinical context. Results: Patients with bone-invasive BCC were elderly (mean age: 75.3 years, SD: 10.94 years) and lesions were typically large (mean diameter 38.9 mm), most frequently located on the nose and forehead. Many cases lacked previous treatment. Smaller nasal tumors were managed with local flaps, while larger lesions on the forehead and temple required skin grafts. Findings from the literature confirm that bone invasion is rare and usually associated with long-standing tumors in anatomically high-risk areas. Conclusions: Although rare, BCC with bone infiltration remains a clinically relevant phenomenon, particularly in elderly patients with advanced or recurrent tumors. Early diagnosis, complete excision with histologically clear margins, and individualized surgical planning are essential to prevent deep tissue involvement. Imaging should be reserved for cases in which advanced local invasion is clinically suspected.

Pain is a common symptom reported by patients during procedures of aesthetic medicine and cosmetic dermatology. Effective analgesia affects not only patient’s satisfaction and comfort, but also effectiveness of the treatment. The variety of available methods of anesthesia enables individualized analgesia depending on the type of surgery and patient’s preferences. The purpose of this article is to present the current and available methods of anesthesia in aesthetic medicine and cosmetic dermatology as a response to the intensive development of this field of medicine. The article below is based on our own observations and the literature found in the pubmed database.

Chronic pain is experienced by the majority of patients with renal insufficiency. Pain management in patients with chronic kidney disease is difficult because a significant part of painkillers is excreted through the kidneys, therefore side effects are more common among this population. The aim of this review is to draw attention to the available pain management options in patients with CKD based on an analysis of published articles. The following article is based on the literature found in the pubmed database. Treatment should include pharmacological, non-pharmacological methods and treatment of comorbidities, whereas patients should be carefully monitored for side effects and possible complications. More research is needed in this area.