Yi-Chang Su

Prof. Yi-Chang Su


Research Focus & Metrics

Academic Career Length

21Years (2006-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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23 April 2012 in PLOS ONE
Verified
Journal Article
Open access
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CSChun-Chuan Shih
Chun-Chuan Shih
CLChien-Chang Liao
Chien-Chang Liao
YSYi-Chang Su
Yi-Chang Su
CTChin-Chuan Tsai
Chin-Chuan Tsai
JLJaung-Geng Lin
Jaung-Geng Lin
The increasing use of complementary, alternative medicine (CAM) and traditional Chinese medicine (TCM) has attracted attention. We report on the gender difference in TCM use among the general population in Taiwan in a population-based, cross-sectional study. We collected data on socio-demographic factors, lifestyle and health behavior from the 2001 Taiwan National Health Interview Survey. The medical records of interviewees aged 20–69 years were obtained from National Health Insurance claims data with informed consent. The prevalence of TCM use and the average frequency of TCM use were compared between women and men. Among 14,064 eligible participants, the one-year prevalence of TCM use for women and men was 31.8% and 22.4%, respectively. Compared with men, women had a higher average TCM use frequency (1.55 visits vs. 1.04 visits, p<0.001). This significant difference remained evident after excluding gender-specific diseases (1.43 visits vs. 1.03 visits, p<0.001). The average TCM use frequency was significantly higher in women than in men across all age groups. TCM use correlates differed for women and men. Marital status (odds ratio [OR] = 1.55, 95% confidence interval [CI] = 1.30–1.85), family income and unhealthy lifestyle (OR = 1.50, 95% CI = 1.30–1.74) were factors associated with TCM use in men but not in women. In Taiwan, women used more TCM services than men and the gender differences in the TCM use profile persisted across age groups.

1 January 2021 in Biomedicine & Pharmacotherapy
Verified
Journal Article
Open access
KTKeng-Chang Tsai
Keng-Chang Tsai
YHYi-Chia Huang
Yi-Chia Huang
CLChia-Ching Liaw
Chia-Ching Liaw
CTChia-I Tsai
Chia-I Tsai
CCChun-Tang Chiou
Chun-Tang Chiou
YSYi-Chang Su
Yi-Chang Su
• A herb-based formula delivers positive clinical outcomes on COVID-19 patients. • The formula inhibits SARS-CoV-2 pathogenesis in anti-viral & -inflammatory assays. • Real-world-evidence offers insights to inform drug development. • Bed-to-bench approach shortens the time required for finding effective therapeutics.

1 December 2012 in European Journal of Integrative Medicine
Verified
Journal Article
Closed access
JLJun-Dai Lin
Jun-Dai Lin
JLJui-Shan Lin
Jui-Shan Lin
LCLi-Li Chen
Li-Li Chen
CCChih-Hung Chang
Chih-Hung Chang
YHYi-Chia Huang
Yi-Chia Huang
YSYi-Chang Su
Yi-Chang Su

1 September 2015 in Medicine
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Journal Article
Open access
CSChun-Chuan Shih
Chun-Chuan Shih
CLChien-Chang Liao
Chien-Chang Liao
MSMao-Feng Sun
Mao-Feng Sun
YSYi-Chang Su
Yi-Chang Su
CWChi-Pang Wen
Chi-Pang Wen
JLJaung-Geng Lin
Jaung-Geng Lin
Little was known about the effects of acupuncture on stroke recurrence. The aim of this study is to investigate whether ischemic stroke patients receiving acupuncture treatment have a decreased risk of stroke recurrence. A retrospective cohort study of 30,058 newly diagnosed cases of ischemic stroke in 2000 to 2004 was conducted based on the claims of Taiwan National Health Insurance Research Database. The use of acupuncture treatment and stroke recurrence were identified during the follow-up period from 2000 to 2009. This study compared the risk of stroke recurrence between ischemic stroke cohorts with and without acupuncture treatment by calculating adjusted hazard ratios (HRs) and 95% confidence intervals (CIs) of acupuncture associated with stroke recurrence in the Cox proportional hazard model. The stroke recurrence rate per 1000 person-years decreased from 71.4 without to 69.9 with acupuncture treatment (P < 0.001). Acupuncture treatment was associated with reduced risk of stroke recurrence (HR 0.88; 95% CI 0.84-0.91). The acupuncture effect was noted in patients with or without medical treatment for stroke prevention but its impact decreased with aging of stroke patients. Compared with stroke patients without acupuncture treatment and medication therapy, the hazard ratios of stroke recurrence for those had medication therapy only, acupuncture only, and both were 0.42 (95% CI 0.38-0.46), 0.50 (95% CI 0.43-0.57), and 0.39 (95% CI 0.35-0.43), respectively. This study raises the possibility that acupuncture might be effective in lowering stroke recurrence rate even in those on medications for stroke prevention. Results suggest the need of prospective sham-controlled and randomized trials to establish the efficacy of acupuncture in preventing stroke.

1 December 2008 in Complementary Medicine Research
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Journal Article
Closed access
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YSYi-Chang Su
Yi-Chang Su
LCLi-Li Chen
Li-Li Chen
JLJun-Dai Lin
Jun-Dai Lin
JLJui-Shan Lin
Jui-Shan Lin
YHYi-Chia Huang
Yi-Chia Huang
JLJim-Shoung Lai
Jim-Shoung Lai
Introduction: Assessing an individual’s level of Yang deficiency (Yang-Xu) by its manifestations is a frequent issue in traditional Chinese medicine (TCM) clinical trials. To this end, an objective, reliable and rigorous diagnostic tool is required. This study aimed to develop a first final version of the Yang-Xu Constitution Questionnaire. Methods: We conducted 3 steps to develop such an objective measurement tool: 1) the research team was formed and a panel of 26 experts was selected for the Delphi process; 2) items for the questionnaire were generated by literature review and a Delphi process; items were reworded into colloquial questions; face and content validity of the items were evaluated through a Delphi process again; 3) the difficulty of the questionnaire was evaluated in a pilot study with 81 subjects aged 20–60 years. Results: The literature review retrieved 35 relevant items which matched the definition of ‘constitution’ and ‘Yang-Xu’. After a first Delphi process, 22 items were retained and translated into colloquial questions. According to the second part of the Delphi process, the content validity index of each of the 22 questions ranged between 0.85–1. These 22 questions were evaluated by 81 subjects, 2 questions that were hard to tell the difference were combined; 3 questions were modified after the research team had discussed the participants’ feedback. Finally, the questionnaire was established with 21 questions. Conclusions: This first final version of a questionnaire to assess Yang-Xu constitution with considerable face and content validity may serve as a basis to develop an advanced Yang-Xu questionnaire.

6 July 2010 in BMC Health Services Research
Verified
Journal Article
Open access
PDF file
CSChun-Chuan Shih
Chun-Chuan Shih
YSYi-Chang Su
Yi-Chang Su
CLChien-Chang Liao
Chien-Chang Liao
JLJaung-Geng Lin
Jaung-Geng Lin
Background: Medical pluralism (MP) can be defined as the employment of more than one medical system or the use of both conventional and complementary and alternative medicine (CAM) for health and illness. A population-based survey and linkage with medical records was conducted to investigate MP amongst the Taiwanese population. Previous research suggests an increasing use of CAM worldwide. Methods: We collected demographic data, socioeconomic information, and details about lifestyle and health behaviours from the 2001 Taiwan National Health Interview Survey. The medical records of interviewees were obtained from National Health Insurance claims data with informed consent. In this study, MP was defined as using both Western medicine and traditional Chinese medicine (TCM) services in 2001. The odds ratio (OR) and 95% confidence interval (CI) were estimated for factors associated with adopting MP in univariate and multiple logistic regression. Results: Among 12,604 eligible participants, 32.5% adopted MP. Being female (OR = 1.44, 95% CI = 1.30 - 1.61) and young (OR = 1.38, 95% CI = 1.15 - 1.66) were factors associated with adopting MP in the multiple logistic regression. People with healthy lifestyles (OR = 1.35, 95% CI = 1.19 - 1.53) were more likely to adopt MP than those with unhealthy lifestyles. Compared with people who had not used folk therapy within the past month, people who used folk therapy were more likely to adopt MP. The OR of adopting MP was higher in people who lived in highly urbanised areas as compared with those living in areas with a low degree of urbanisation. Living in an area with a high density of TCM physicians (OR = 2.19, 95% CI = 1.69 - 2.84) was the strongest predictor for adopting MP. Conclusion: MP is common in Taiwan. Sociodemographic factors, unhealthy lifestyle, use of folk therapy, and living in areas with a high density of TCM physicians are all associated with MP. People who had factors associated with the adoption of MP may be at risk for adverse health effects from interactions between TCM herbal medicine and WM pharmaceuticals.