INTRODUCTION: Goji berry has long been used as a healthy aliment for healthy vision, strengthening the immune system, protecting the liver, improving circulation, remedy for diabetes, enhancing sexual performance and general health. But there are not enough study on its constituents, pharmacology and safety. CASE REPORT: This case report describes a 24-year-old female patient was admitted to emergency service due to complaints of nausea, vomiting and abdominal pain. Ictherus at sclera and sensivitiy on the right upper quadrant of abdomen were found on the physical examination. Blood tests revealed high liver function tests. The causes of jaundice and impaired liver function were all excluded and toxic hepatitis due to goji berry consumption was considered in patient. CONCLUSION: Goji berry is a traditional nutrient that is increasingly used for its various effects. To date, there are some articles declared allergic reactions as toxic effect. To our knowledge this case is the first publication that goji berries can be toxic to the liver. Although larger studies are required, it should be kept in mind that liver toxicity may occur during intensive use.

Does Lactate Dehydrogenase Act as an Early Warning System Predicting Mortality in Trauma Patients? - Eurasian Journal of Emergency Medicine

Background/Objectives: Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) continues to pose a significant global health challenge due to its high transmissibility and potential for severe clinical outcomes. Early identification of patients at risk of hospitalization is essential for effective triage in emergency departments and for the optimal allocation of healthcare resources. Methods: This prospective study included 84 patients aged over 18 years who presented to the emergency department on 23 December 2020, with suspected SARS-CoV-2 infection. Initially, 100 patients were evaluated, and 16 were excluded based on predefined exclusion criteria. The mean age of the participants was 53.65 ± 13.62 years, and 39 (46.4%) were women. Results: At admission, the mean signal peptide, CUB domain, EGF (SCUBE-1) level among SARS-CoV-2 patients was 0.16 ± 0.08 ng/mL. There was no significant difference in SCUBE-1 levels between patient and control groups (n = 59 vs. 25), but levels differed significantly between hospitalized and home-treated patients (n = 37 vs. 22; p = 0.001). Neutrophil count (p = 0.001) and NLR (p = 0.010) were higher in patients than controls and also higher in hospitalized than home-treated patients (p = 0.003 and p = 0.015). ROC analysis revealed that SCUBE-1 predicted hospitalization with 84.6% sensitivity and 88.9% specificity. A positive correlation was observed between SCUBE-1 levels and length of hospital stay (p = 0.007, r = 0.554), with a median stay of 9.0 (5.0–11.0) days. Conclusions: SCUBE-1 levels were significantly associated with disease severity in SARS-CoV-2 patients and may serve as a promising biomarker to support clinical decision-making for hospitalization versus home-based management.

Objective In our study, we evaluated central venous catheter procedures performed by Adnan Menderes University, Department of Emergency Medicine in the emergency room and emergency intensive care units. We planned to investigate performing central venous catheter application with ultrasound guidance and the rate of bleeding complications in patients using anticoagulants or antiplatelet. Material and Method Between 15.11.2018-15.10.2019, central venous catheter application was performed 178 cases over the age of 18 and non-pregnant were included. Research data were evaluated by using SPSS 21.0 statistics program. Results A Central venous catheter procedure was performed in 78.7% of the patients with ultrasound guidance. 36.5% of the patients had a history of anticoagulant or antiplatelet drug use. The most common complications in our patients were ventricular dysrhythmia and subcutaneous hematoma. Conclusion In conclusion, when looking at the relationship between gender, anticoagulant and/or antiplatelet drug use, preferred vein and ultrasound use during the procedure, and complication status, no statistically significant results were found.