The bioassay guided fractionation of methanolic extract of Murraya koenigii (L.) Spreng. leaves resulted in the isolation of seven pyranocarbazoles. These were evaluated against four bacterial strains and ten Candida sp. including two matched pair of fluconazole sensitive/resistant clinical isolates. Out of seven, three i.e. Koenine (mk279), Koenigine (mk309) and Mahanine (mk347) exhibited significant antibacterial activity MIC90 3.12–12.5 μg/mL against bacterial strains Streptococcus aureus and Klebsiella pneumonia compared with standard drug Kanamycin MIC90 12.5 μg/mL. However, only mk309 was found active against variety of Candida species MIC90 12.5–100 μg/mL. It was observed that hydroxylation at C-6 and C-7 positions in the studied pyranocarbazoles activate the bioactivity. Simultaneously, decrease in Log P value compares with −H and −O−CH3 substituted derivatives. The study is focused on selective antifungal and antibacterial activity of pyranocarbazoles on bacterial strains S. aureus, K. pneumonia and variety of Candida species with structure activity relationship observations.

Rapid urbanisation has led to a dramatic increase in sewage sludge production. There are limited methods of managing sewage sludge along with high energy and monetary investment. A cost-effective, environment-friendly, and sustainable solution needs to be developed for the management of sewage sludge. In the current study, sludge from the Jagjeetpur sewage treatment plant (STP) had been collected, composted, and characterized during January and February 2022. A comparison of STP sludge compost and compost made from farmyard manure showed the presence of essential agricultural nutrients in them, due to which they find application for plant growth. Two products, Jaivik Poshak and Jaivik Prom, containing farmyard compost, were compared with the amended version of the same, containing compost from STP sludge instead of normal compost. The results showed that the modified Jaivik Poshak was the best for maintaining pH and increasing electrical conductivity. The available nitrogen in the soil upon its application increased by 1.6 times ($p<0.001$) with respect to control, and it brought about 100% tomato seed germination within sixteen days. The above finding has been validated by goodness of fit value, factor analysis, and hierarchical analysis. The product, modified Jaivik Prom increased organic carbon content and brought about 5.81 and 8 times the enhancement in available phosphorous ($p<0.001$) and potassium ($p<0.001$) content in soil, respectively, with respect to the control set. The heavy metal content in the soil as a result of all types of treatment was within the permissible limit. This study thus proves that sludge from STP may be used for agricultural uses after proper fortification and testing to convert waste to wealth along with environmental sustenance.

The Ganga basin is witnessing accelerated deterioration of agricultural fields, with severe soil erosion leading to nutrients leaching into the river, wreaking havoc on the river's ecosystems. Many Ganga River management plans have been implemented in the past, but a more coordinated and integrated effort that tries to implement basin management strategies with technology preparedness considered critical for the preservation of agricultural regions had been lacking. The Namami Gange Program (NGP) is a first of its kind integrated conservation mission pillared on sustainable water management policies and practices, launched in 2014. Unfortunately, scientific literature on its overall functioning and progress is almost non-existent. This review presents its overall functioning, critically analyses its associated components, and presents case studies, pilot studies, along with analytical critiques. An objective analytical evaluation of the NGP has been provided concluding with sectoral interventions. We have concluded that the ambitions for boosting energy production, irrigation, manufacturing, and expanding the river as an inland waterway interfere with the Ganga cleanup because they are both part of the growth strategy pushed by the administration.

Background: Fundamentally, there are several levels of complexities associated with the digitalization of the agriculture sector. In the context of the Indian agricultural sector, the contemporary efforts towards E-Governance are helping a progressive digitization process to be realized through the comprehensive National E-governance Plan for Agriculture (NeGP-A), one of the Indian government's Multimodal Projects (MMPs). The cornerstone of the recent digital push in agriculture through the India Digital Ecosystem of Agriculture (IDEA) framework is Digital AgriStack, an amalgamation of digital technologies and databases concentrating on farmers and the agricultural industry. Purpose: Intriguingly, there is just a handful of explorative research to gain in-depth ideas on administrative efforts regarding E-governance activities in the Indian agricultural sector. Hence, a stringent effort has been made to cover all facets of E-government in Indian agriculture, beginning with its inception, advancement, and present status as well as a synergy between the center and the states across the domains of G2G, G2F, G2B, and B2F, for the first time. Findings: The review presents a comprehensive list of the E-governance initiatives categorized across the four domains of governance and draws a clear picture of the Indian state of e-governance in agriculture while presenting the advancements and challenges at a global and local scale. Originality: To the best of our knowledge, no such rigorous attempt has previously been made to analyze and comprehensively present as well as categorize the Indian E-governance facets in the agricultural sector. This will certainly add to the emerging knowledge in the respective E-gov agricultural domains and their applications in developing nations across the globe.