Sofianos Andrikopoulos

Dr. Sofianos Andrikopoulos


Research Focus & Metrics

Academic Career Length

7Years (2020-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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29 August 2022 in Obesity Research & Clinical Practice
Verified
Journal Article
Open access
TMTania Paulette Markovic
Tania Paulette Markovic
JPJoseph Proietto
Joseph Proietto
JDJohn B. Dixon
John B. Dixon
GRGeorgia Rigas
Georgia Rigas
GDGary Deed
Gary Deed
SCStephen Colagiuri
Stephen Colagiuri
Obesity is a complex and multifactorial chronic disease with genetic, environmental, physiological and behavioural determinants that requires long-term care. Obesity is associated with a broad range of complications including type 2 diabetes, cardiovascular disease, dyslipidaemia, metabolic associated fatty liver disease, reproductive hormonal abnormalities, sleep apnoea, depression, osteoarthritis and certain cancers. An algorithm has been developed (with PubMed and Medline searched for all relevant articles from 1 Jan 2000-1 Oct 2021) to (i) assist primary care physicians in treatment decisions for non-pregnant adults with obesity, and (ii) provide a practical clinical tool to guide the implementation of existing guidelines (summarised in Appendix 1) for the treatment of obesity in the Australian primary care setting. MAIN RECOMMENDATIONS AND CHANGES IN MANAGEMENT: Treatment pathways should be determined by a person's anthropometry (body mass index (BMI) and waist circumference (WC)) and the presence and severity of obesity-related complications. A target of 10-15% weight loss is recommended for people with BMI 30-40 kg/m2 or abdominal obesity (WC > 88 cm in females, WC > 102 cm in males) without complications. The treatment focus should be supervised lifestyle interventions that may include a reduced or low energy diet, very low energy diet (VLED) or pharmacotherapy. For people with BMI 30-40 kg/m2 or abdominal obesity and complications, or those with BMI > 40 kg/m2 a weight loss target of 10-15% body weight is recommended, and management should include intensive interventions such as VLED, pharmacotherapy or bariatric surgery, which may be required in combination. A weight loss target of > 15% is recommended for those with BMI > 40 kg/m2 and complications and they should be referred to specialist care. Their treatment should include a VLED with or without pharmacotherapy and bariatric surgery.

1 July 2020 in Diabetes Research and Clinical Practice
Verified
Journal Article
Closed access
SASofianos Andrikopoulos
Sofianos Andrikopoulos
GJGreg Johnson
Greg Johnson

1 February 2026 in Diabetology
Verified
Journal Article
Open access
PDF file
SLShanshan Lin
Shanshan Lin
GDGary Deed
Gary Deed
.K.Chee Leong Khoo
.Chee Leong Khoo
Giuliana MurfetGiuliana Murfet
Giuliana Murfet
ABAlan Barclay
Alan Barclay
SASofianos Andrikopoulos
Sofianos Andrikopoulos
Background/Objectives: Achieving a balanced wholefood diet while stabilising glycaemic management is challenging for many people with type 2 diabetes (T2D) due to barriers such as food preparation skills, time, and medication effects. Diabetes-specific nutritional formulas (DSNFs) are nutritionally complete products designed to support glycaemic management and overall nutritional adequacy and may complement wholefood dietary approaches when these are not feasible or are insufficient. Despite growing clinical evidence of efficacy, practical guidance for routine use is limited. Methods: A multidisciplinary expert working group developed a Clinical Practice Guide (CPG) for integrating DSNFs into diabetes care. Development was informed by a literature review and iterative consensus among experts, including representatives of the Australian Diabetes Society, Australian Diabetes Educators Association, and the Royal Australian College of General Practitioners. Results: The CPG outlines a three-step pathway: (1) assess suitability (clinical indications, contraindications, preferences, cultural context); (2) tailor the approach (individual goals, dose/timing relative to weight and body composition goals and observed glycaemic patterns, integration with lifestyle care); and (3) monitor progress (baseline, 2–4 weeks to assess initial response, then 3, 6, and 12 months for glycaemic indices, weight/body composition where available, and medication review). Conclusions: This CPG provides practical, multidisciplinary guidance for the person-centred use of DSNFs as an adjunct to standard care, supporting translation of current evidence into clinical practice and promoting consistent, multidisciplinary implementation.

20 January 2026 in Preprints.org
Verified
Preprint
Open access
PDF file
SLShanshan Lin
Shanshan Lin
GDGary Deed
Gary Deed
.K.Chee Leong Khoo
.Chee Leong Khoo
Giuliana MurfetGiuliana Murfet
Giuliana Murfet
ABAlan Barclay
Alan Barclay
SASofianos Andrikopoulos
Sofianos Andrikopoulos
Background/Objectives: Achieving a balanced wholefood diet while stabilising glycae-mic management is challenging for many people with type 2 diabetes (T2D) due to barri-ers such as food preparation skills, time, and medication effects. Diabetes-specific nutri-tional formulas (DSNF) are nutritionally complete products designed to support glycae-mic management and overall nutritional adequacy and may complement wholefood die-tary approaches when these are not feasible or are insufficient. Despite growing clinical evidence of efficacy, practical guidance for routine use is limited. Methods: A multidisci-plinary expert working group developed a Clinical Practice Guide (CPG) for integrating DSNF into diabetes care. Development was informed by a literature review and iterative consensus among experts, including representatives of the Australian Diabetes Society, Australian Diabetes Educators Association, and the Royal Australian College of General Practitioners. Results: The CPG outlines a three-step pathway: (1) Assess suitability (clinical indications, contraindications, preferences, cultural context); (2) Tailor the approach (indi-vidual goals, dose/timing relative to weight and body composition goals and observed glycaemic patterns, integration with lifestyle care); and (3) Monitor progress (baseline, 2–4 weeks to assess initial response, then 3, 6, and 12 months for glycaemic indices, weight/body composition where available, and medication review). Conclusions: This CPG provides practical, multidisciplinary guidance for the person-centred use of DSNF as an adjunct to standard care, supporting translation of current evidence into clinical prac-tice and promoting consistent, multidisciplinary implementation.