The wire Laser-based Directed Energy Deposition (DED-LB) metal additive manufacturing (AM) process is time- and cost-effective, providing high-quality, dense parts while supporting multi-scale manufacturing, repair, and repurposing services. However, its ability to consistently produce parts of uniform quality depends on process stability, which can be achieved through monitoring and controlling key process phenomena, such as heat accumulation and variations in the distance between the deposition head and the working surface (standoff distance). Part quality is closely linked to achieving predictable melt pool dimensions and stable thermal conditions, which in turn influence the end-part’s cross-sectional stability, overall dimensions, and mechanical properties. This work presents a workflow that correlates process and metrology data, enabling the determination of tunable process parameters and their operating process window. The process data are acquired using a vision-based monitoring system and a load-cell embedded in the deposition head, which together detect variations in melt pool area and standoff distance during the process, while metrology devices assess the part quality. Finally, this monitoring setup and its ability to capture the complete process history are fundamental for developing in-line control strategies, enabling optimized, supervision-free, and repeatable processes.