Michael Cardinale

Dr. Michael Cardinale

orcid

Research Focus & Metrics

Academic Career Length

10Years (2017-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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5 August 2019 in Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
Verified
Journal Article
Open access
PDF file
ACArnaud Cassignol
Arnaud Cassignol
JMJulien Marmin
Julien Marmin
JCJean Cotte
Jean Cotte
MCMichael Cardinale
Michael Cardinale
JBJulien Bordes
Julien Bordes
EMEric Meaudre
Eric Meaudre
In France, the pre-hospital field triage of trauma patients is currently based on the Vittel criteria algorithm. This algorithm was originally created in 2002 before the stratification of trauma centers and, at the national level, has not been revised since. This could be responsible for the overtriage of trauma patients in Level I Trauma Centers. The principal aim of this study was to evaluate the correlation between each Vittel field triage criterion and trauma patients’ Injury Severity Score. Our Level I Trauma Center receives an average of 300 trauma patients per year. Demographic and physiological data, along with the entire trauma patient management process and Vittel field triage criteria, are recorded in a local trauma registry. The Abbreviated Injury Scale (AIS) and Injury Severity Score (ISS) are calculated after a complete assessment of the trauma victim during their in-hospital management. Results were concerned with the presence of an ISS of greater than 15, which defined a major trauma patient; mortality within 30 days; and admission to the intensive care unit. This study is a registry analysis from January 2013 to September 2017. Of the 1373 patients in the registry, 1151 were included in the analysis with a mean age of 43 years (± 19) and a median ISS of 13 (IQR = 5–22), where 887 (77%) were male. Nine of the 24 Vittel criteria were associated with an ISS > 15. In a multivariate analysis, no criterion related to kinetic elements was significantly correlated with an ISS > 15, mortality within 30 days, or admission to intensive care. Three algorithm categories were predictive of a major trauma patient (ISS > 15): physiological variables, pre-hospital resuscitation, and physical injuries, while kinetic elements were not. Criteria related to physiological variables, pre-hospital resuscitation, and physical injuries are the most relevant to predicting the severity of a trauma patient’s condition. A revision of the VCA could potentially have beneficial effects on the over and undertriage phenomena, which constitute ongoing medical and financial concerns.

7 January 2019 in Prehospital Emergency Care
Verified
Journal Article
Closed access
ACArnaud Cassignol
Arnaud Cassignol
TMThibaut Markarian
Thibaut Markarian
JCJean Cotte
Jean Cotte
JMJulien Marmin
Julien Marmin
CNCédric Nguyen
Cédric Nguyen
XBXavier Bobbia
Xavier Bobbia
Introduction: Several prehospital major trauma patient triage scores have been developed, the triage revised trauma score (T-RTS), Vittel criteria, Mechanism/Glasgow Coma Scale/Age/Systolic blood pressure score (MGAP) and the new trauma score (NTS). These scoring schema allow a rapid and accurate prognostic assessment of the severity of potential lesions. The aim of our study was to compare these scores with in-hospital mortality predictions in a cohort of consecutive trauma patients admitted in a Level 1 trauma center. Materials: Between 2013 and 2016, 1,112 patients were admitted to the "major trauma" spinneret of a Level 1 trauma center in the south of France. All prehospital data needed to calculate the T-RTS, Vittel criteria, the MGAP score and the NTS were collected. The main evaluation criterion was in-hospital mortality at 30 days for all causes. The predictive performances of these scores were evaluated and compared with each other using the analysis of the receiver operating curves. Results: A total of 1,001 patients were included in the analysis, 238 (24%) females, aged 43 ± 19 years with ISS 15 ± 13. The area under the curve was for each score: T-RTS, AUC =0.84, [0.82–0.87]; Vittel criteria, AUC =0.87 [0.85–0.89]; MGAP score, AUC =0.91 [0.89–0.92] and NTS, AUC =0.90 [0.88–0.92]. By comparing the ROC curves of these scores, the MGAP and NTS scores were statistically higher than the T-RTS. With the current thresholds, the sensitivity, specificity, positive and negative predictive values of these scores were 91%, 35%, 10%, 98% for T-RTS, 100%, 2%, 8%, 100% for Vittel criteria, 91%, 71%, 24%, 99% for MGAP score, 82%, 86%, 33%, 98% for NTS. Only Vittel's criteria allowed undertriage below 5% as recommended by the American College of Surgeons Committee on Trauma (ACSCOT). Conclusion: The comparison of these different triage scores concluded with a superiority of the MGAP and NTS scores compared with the T-RTS. Including the calculation of MGAP or NTS scores with the Vittel criteria would reduce the risk of overtriage in the Level 1 trauma centers by further directing patients at low risk of death to a lower-level trauma facility.

11 February 2022 in Critical Care Medicine
Verified
Journal Article
Closed access
MCMichael Cardinale
Michael Cardinale
SBSalah Md Boussen
Salah Md Boussen
PCPierre-Julien Cungi
Pierre-Julien Cungi
PEPierre Md Esnault
Pierre Md Esnault
QMQuentin Mathais
Quentin Mathais
PGPhilippe Goutorbe
Philippe Goutorbe
OBJECTIVES: ICUs have had to deal with a large number of patients with acute respiratory distress syndrome COVID-19, a significant number of whom received prone ventilation, which is a substantial consumer of care time. The selection of patients that we have to ventilate in prone position seems interesting. We evaluate the correlation between the percentage of collapsed dependent lung areas in the supine position, monitoring by electrical impedance tomography and the oxygenation response (change in Pao 2/Fio 2 ratio) to prone position. DESIGN: An observational prospective study. SETTING: From October 21, 2020, to 30 March 30, 2021. At the Sainte Anne military teaching Hospital and the Timone University Hospital. PATIENTS: Fifty consecutive patients admitted in our ICUs, with COVID-19 acute respiratory distress syndrome and required mechanical, were included. Twenty-four (48%) received prone ventilation. Fifty-eight prone sessions were investigated. INTERVENTIONS: An electrical impedance tomography recording was made in supine position, daily and repeated just before and just after the prone session. The daily dependent area collapse was calculated in relation to the previous electrical impedance tomography recording. Prone ventilation response was defined as a Pao 2/Fio 2 ratio improvement greater than 20%. MEASUREMENT AND MAIN RESULTS: The main outcome was the correlation between dependent area collapse and the oxygenation response to prone ventilation. Dependent area collapse was correlated with oxygenation response to prone ventilation (R 2 = 0.49) and had a satisfactory prediction accuracy of prone response with an area under the curve of 0.94 (95% CI, 0.87–1.00; p < 0.001). Best Youden index was obtained for a dependent area collapse greater than 13.5 %. Sensitivity of 92% (95% CI, 78–97), a specificity of 91% (95% CI, 72–97), a positive predictive value of 94% (95% CI, 88–100), a negative predictive value of 87% (95% CI, 78–96), and a diagnostic accuracy of 91% (95% CI, 84–98). CONCLUSIONS: Dependent lung areas collapse (> 13.5%), monitored by electrical impedance tomography, has an excellent positive predictive value (94%) of improved oxygenation during prone ventilation.

1 August 2020 in Anaesthesia Critical Care & Pain Medicine
Verified
Journal Article
Closed access
MCMichael Cardinale
Michael Cardinale
PEPierre Esnault
Pierre Esnault
JCJean Cotte
Jean Cotte
PCPierre J. Cungi
Pierre J. Cungi
PGPhilippe Goutorbe
Philippe Goutorbe

25 September 2023 in European Journal of Trauma and Emergency Surgery
Verified
Journal Article
Closed access
PDF file
MRMarion Robaix
Marion Robaix
QMQuentin Mathais
Quentin Mathais
HMHilaire de Malleray
Hilaire de Malleray
SGSarah Guigues
Sarah Guigues
EMEric Meaudre
Eric Meaudre
MCMichael Cardinale
Michael Cardinale

23 November 2019 in Injury
Verified
Journal Article
Closed access
PDF file
MCMichael Cardinale
Michael Cardinale
PCP.J. Cungi
P.J. Cungi
PEP. Esnault
P. Esnault
CNC. Nguyen
C. Nguyen
JCJ. Cotte
J. Cotte
EME. Meaudre
E. Meaudre