Marioara Druga

Dr. Marioara Druga


Research Focus & Metrics

Academic Career Length

1Year (2026-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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4 January 2026 in Plants
Verified
Journal Article
Open access
PDF file
MFMarinela Fițoiu-Voin
Marinela Fițoiu-Voin
MAMateut Anamaria
Mateut Anamaria
VVVladu Elena Viorica
Vladu Elena Viorica
RPRoxana Liliana Poja
Roxana Liliana Poja
LTLavinia-Alexandra Toporîşte
Lavinia-Alexandra Toporîşte
DHDaniel Hădărugă
Daniel Hădărugă
The influence of natural β-cyclodextrin (β-CD) on the overall antioxidant activity of berry extracts is presented in this study. Raw raspberry (Rubus idaeus L.) and β-CD-assisted dehydrated strawberry (Fragaria × ananassa Duch.) ethanolic extracts (RB and SB, respectively) were spectrophotometrically monitored in the presence of 1 mM 2,2-diphenyl-1-picrylhydrazyl (DPPH·) solution in the absence or presence of β-CD. Cyanidin 3-O-glucoside (Cy3G) was used as standard compound, being identified by RP-HPLC in both RB and SB at 14.62 and only 0.15 mg/100 g fresh weight (fw). Pelargonidin 3-O-glucoside (Plg3G) was the most concentrated anthocyanin in SB (estimated at 2.46 mg/100 g fw). Higher antioxidant activities (expressed as the radical scavenging activity, RSA, %) were obtained for SB dehydrated in the presence of β-CD. The RSA values increased by 35% in comparison with the SB dehydrated by the classical method. On the other hand, the DPPH· reaction kinetic parameters significantly differed for RB extracts evaluated in the presence of 1 mM β-CD (in water). The DPPH· reaction rate in the 3–15 min time range was 25% higher for the RB extracts obtained from the β-CD-assisted dehydrated samples. This study demonstrates for the first time the protection capacity of β-CD against the degradation of antioxidants during the classical dehydration process of berries. This technology can be extended to other fruits and scaled up for obtaining high-quality fruit-based products.

30 September 2026 in Antibiotics
Verified
Journal Article
Open access
PDF file
VDVictor Andrei Drugă
Victor Andrei Drugă
MDMarioara Druga
Marioara Druga
MȘMaria Șorop-Florea
Maria Șorop-Florea
RSRazvan Susan
Razvan Susan
MSMonica Maria Susan
Monica Maria Susan
VOValentin Laurențiu Ordodi
Valentin Laurențiu Ordodi
Background: Medically relevant biofilms are difficult to detect, characterize, and eradicate because their behavior depends on microbial species, biofilm maturity, extracellular matrix, surface properties, and environmental conditions. Physicochemical approaches provide complementary strategies for monitoring biofilm development and for preventing or disrupting established communities. This structured narrative review examines electrical and electrochemical methods, ultrasound, light-based and photodynamic treatments, plasma and thermal approaches, nanomaterials and photocatalysis, surface modification, and physicochemical detection methods, with particular emphasis on magnetic-field-based strategies. Contemporary primary studies published from January 2025 to July 2026 were considered together with selected earlier studies providing methodological or comparative context. Findings: Physicochemical approaches produced substantial effects across bacterial and fungal biofilm models, but outcomes were strongly dependent on experimental conditions and assessment methods. Cultivability, biomass, metabolic activity, adhesion, detachment, architecture, and physicochemical signals represent distinct aspects of biofilm behavior and should not be interpreted interchangeably. Real-time monitoring methods provide valuable temporal information but require validation against biological endpoints. Magnetic approaches particularly illustrate this methodological heterogeneity. Direct magnetic-field exposure produced variable and incompletely standardized responses, whereas magnetothermal, magnetomechanical, and magnetically guided systems generally showed more consistently quantified antibiofilm effects. Further progress requires standardized physicochemical characterization, appropriate mechanistic controls, clinically representative models, and complementary assessment of biofilm viability, biomass, structure, and regrowth.