The perception of personal barriers to physical activity varies according to the sociodemographic characteristics of individuals. To determine the predictors of the perception of barriers to physical activity in the adult population. A cross-sectional study with 1066 adult women and 1036 adult men. The sociodemographic variables (age, gender, marital status, socioeconomic level, level of education), the perception of barriers that do not allow performance of physical activity (i.e. lack of time, social support, energy, motivation, skill, resources, and fear of injury during practice); and the level of physical activity through the International Physical Activity Questionnaire in its short-form version were evaluated. Individuals from low socioeconomic level (1 and 2) have higher risks of perceiving barriers such as lack of motivation [OR 1.76 (95% CI (1.4-2.1))] and lack of resources [OR 1.37 (95% CI (1.1-1.6))]; individuals with partners did not perceive the lack of social support [OR 0.29 (95% CI (0.2-0.4))] and lack of motivation [OR 0.54 (95% CI (0.4-0.7))] as barriers to physical activity. Individuals with low schooling perceived lack of social support [OR 3.81 (95% CI (3-4.7))], lack of resources [OR 2.78 (95% CI (2.2-3.3))], and fear of injury [OR 2.70 (95% CI (2.2-3.3))] as barrier to physical activity. Factors such as socioeconomic level, marital status, level of education, and self-perception of health are predictors of barriers to physical activity.

Isometric handgrip or (wall) squat exercise performed three times per week produces reductions in systolic blood pressure (SBP) in adults with hypertension. We aimed to compare these interventions and the potential to retain benefits with one exercise session per week. We compared blood pressure changes following handgrip and squat isometric training interventions with controls in a randomized controlled multicentre trial in 77 unmedicated hypertensive (SBP ≥ 130 mmHg) adults. Exercise sessions were performed in the workplace and consisted of four repetitions—three sessions per week for the first 12 weeks (phase 1), and one session per week for the subsequent 12 weeks (phase 2). Office blood pressure (BP) was measured at baseline, post‐phase 1 and post‐phase 2. Post‐phase 1, mean reductions in SBP were significantly greater in handgrip (–11.2 mmHg, n = 28) and squat (–12.9 mmHg, n = 27) groups than in controls (–.4 mmHg; n = 22) but changes in DBP were not. There were no significant within‐group changes during phase 2 but SBP was 3.8 mmHg lower in the wall squat than the handgrip group—a small magnitude but clinically important difference. While both interventions produced significant SBP reductions, the wall squat appears to be more effective in maintaining benefits with a minimal training dose. The low time investment to achieve and retain clinically significant SBP reductions—42 and 12 min, respectively—and minimal cost, particularly of the wall squat, make it a promising intervention for delivery in public health settings.

Aging is a time-dependent inevitable process, in which cellular homeostasis is affected, which has an impact on tissue function. This represents a risk factor for the development of numerous non-transmissible diseases. In consequence, the scientific community continues to search for therapeutic measures capable of improving quality of life and delaying cellular aging. At the center of this research is metformin, a widely used drug in Type 2 Diabetes Mellitus treatment that has a reduced adverse effects profile. Furthermore, there is evidence that this drug has beneficial health effects that go beyond its anti-hyperglycemic properties. Among these effects, its geronto-protection capability stands out. There is growing evidence that points out to an increased life expectancy as well as the quality of life in model organisms treated with metformin. Therefore, there is an abundance of research centered on elucidating the mechanism through which metformin has its anti-aging effects. Among these, the AMPK, mTORC1, SIRT1, FOXO, NF.kB, and DICER1 pathways can be mentioned. Furthermore, studies have highlighted the possibility of a role for the gut microbiome in these processes. The next step is the design of clinical essays that have as a goal evaluating the efficacy and safety of metformin as an anti-aging drug in humans to create a paradigm in the medical horizon. The question being if metformin is, in fact, the new antiaging therapy in humans?

Physical inactivity is an important risk factor for chronic diseases in Western societies. To determine the sociodemographic and motivational factors associated with physical activity in college students. The International Physical Activity Questionnaire (IPAQ) -short form- and the "motives for physical activities measure-revised" (MPAM-R) questionnaire were applied to 900 university students aged 20 ± 3 years (60% women). The frequency, level and motivations for engaging in physical activity and associated demographic factors were analyzed. Twenty two percent of students were classified as having a high level of physical activity, 54.8% had a low level and 13.9% were considered inactive. According to MET consumption, 68.9% of students are inactive and only 16.8% of students classified as very active. Ninety two percent of active students performed physical activity for health reasons. A significant association between gender and social motivation was observed. A high prevalence of physical inactivity was found in these students. Males showed higher levels of physical activity than females.

Objetivo Identificar a través de un método de medición directo de la actividad física, las categorías en las que se ubican un grupo de estudiantes universitarios; así como relacionar estas categorías con variables de tipo sociodemográfico y antropométrico.Métodos Estudio de corte transversal y fase comparativa en 601 estudiantes universitarios a los que se les indagó sobre las variables sociodemográficas: género, edad, estado civil y estrato socioeconómico y autopercepción de salud. Se determinó el Índice de Masa Corporal y los niveles de actividad física mediante el Test de Clasificación de Sedentarismo de Pérez-Rojas-García sobre el comportamiento de la frecuencia cardíaca.Resultados Se observó diferencias significativas (p=0,000) en la frecuencia cardíaca entre activos e inactivos, en los inactivos fue de 143,4 p/m en comparación con 115,1 p/m en los activos. Con respecto a los resultados de la regresión logística, los estudiantes de género femenino presentan mayor riesgo de ser inactivos físicamente con la prueba objetiva [OR 2,6 (1,9-3,6)]; asimismo, se observa que las personas con sobrepeso y obesidad tienen mayor probabilidad de ser inactivos [OR 1,9 (1,4-2,9)].Conclusión Se evidencia una elevada frecuencia de inactividad física en la población universitaria, asociada significativamente a la obesidad y al género femenino, datos que se convierten en una línea de base fundamental para la elaboración de programas de entrenamiento y actividad física específicos para población universitaria.

Antecedentes. La calidad de vida relacionada con la salud se puede afectar en personas con enfermedad renal crónica.Objetivo. Determinar la calidad de vida relacionada con la salud de los pacientes con enfermedad renal crónica (ERC) y su relación con variables sociodemográficas y datos clínicos.Materiales y métodos. Estudio analítico de corte transversal realizado en 80 personas con diagnóstico de enfermedad renal crónica. Participaron los pacientes que asistieron a la Unidad Renal y al servicio de hospitalización durante los meses de estudio. Se aplicó el cuestionario Kidney Disease Quality of Life (KDQOL-SF), valorando ocho dimensiones genéricas de la calidad de vida relacionada con la salud y tres específicas relacionadas con la enfermedad renal. Se compararon las variables socio demográficas y las relacionadas con la enfermedad con las dimensiones del KDQOOL-36. Resultados. El 23.5% de la población estudiada tenía entre 61 y 70 años y 51.3% eran hombres. Se obtuvieron promedios bajos en las dimensiones carga de la enfermedad renal (40.3), salud física (33.4) y salud mental (43.5) del componente genérico. Se encontró una correlación significativa de la edad con las dimensiones efectos de la enfermedad renal en la vida diaria (0.238, p=0.03) y el componente genérico salud física (-0.242, p=0.03). Un trabajo remunerado se correlacionó positivamente con los componentes genéricos salud física (0.499, p=0.001) y salud mental (0.375, p=0.001) y la carga de la enfermedad renal se correlacionó negativamente con el tiempo de diagnóstico de enfermedad renal (-0.241, p=0.02). Conclusión. La enfermedad renal crónica tiene una carga sobre la calidad de vida de los pacientes en términos de salud física, salud mental y carga de la enfermedad.