Background: The European Association of Urology (EAU) defines primary urethral carcinoma (PUC) as a carcinoma that arises in the urethra without a previous diagnosis of carcinoma elsewhere in the urinary system. It is considered as a rare cancer, accounting for less than 1% of all malignant tumors and 5% of malignant tumors of the urinary system. The difficulty in diagnosis and its rarity can lead to delayed diagnosis and decreased survival. We think that a case report to be made in the literature for this rare disease with no consensus on treatment will contribute to disease management. Case presentation: In this article, we describe the diagnosis and treatment process of a 75-year-old patient who was diagnosed with primary urethral cancer and had urethral discharge and difficulty in urination. The biopsy result from the suspected hyperemic area in the urethra in cystourethroscopy was primary urethral cancer. Urethrectomy followed by urethroplasty was performed on the patient's 2-cm primary urethral cancerous tissue. In the postoperative first month, an F-18 FDG whole-body PET scan for oncological evaluation showed increased pathological F-18 FDG uptake in the periphery of the mass in the penile urethra and indistinguishable boundaries from the prostatic urethra. After this, adjuvant gemcitabine and carboplatin therapy was planned by the oncology team. Conclusions: Based on our outcome in this case, we believe that chemotherapy combined with surgery increases the chance of successful treatment in locally advanced urethral cancer.

Objective: Bladder outlet obstruction is a relatively rare problem in women. Experience in diagnosing and managing female urethral stricture disease is limited. The literature emphasizes that urethral dilatation is usually not successful, but surgical reconstruction is successful. Physicians and patients want to obtain information from social media because surgery cannot be performed in every center. With this study, we aimed to make an integrative review of the quality of the information in YouTube videos in the field of female urethroplasty. Material and Method: Using the keyword female urethroplasty, we searched https://www.youtube.com/ for the last 5 years. Video features, quality, and reliability analysis were performed. The reliability and quality of the medical information in the videos were determined by the JAMA (Journal of American Medical Association) scoring system, the Global Quality Score (GQS), and the DISCERN questionnaire. Results: 39 videos out of a total of 49 were included in the study. India was the country with the most video uploads (43.6%). There was no significant correlation between DISCERN score and the number of views and video comment count (rho;-0.101 p=0.539, rho;0.018 p=0.924, respectively). The DISCERN score, GQS, and JAMA scores of videos from Academic institutions or societies were found to be higher than personal videos (p=0.037, p=0.037, p=0.001, respectively). Conclusion: Although there are limited videos about female urethroplasty on YouTube, the accuracy and reliability of the medical information in the most watched videos are low.