Dysfunctional breathing (DB) with or without an underlying medical condition is associated with impaired quality of life. DB-related symptoms can be measured with the 25-item Self Evaluation of Breathing Questionnaire (SEBQ). However, the SEBQ is not available in Danish.The aim of the present study was to translate and cross-culturally adapt the SEBQ into Danish and to assess the face validity of the Danish version of the questionnaire in individuals with DB-related symptoms. The SEBQ was translated and cross-culturally adapted into Danish using an internationally acknowledged six-step forward-backward translation guideline in an interactive process with an expert committee of clinicians, translators, methodologists and the SEBQ developer. Face validity was explored through semi-structured interviews with 24 adult individuals with DB-related symptoms (age 20–70 years, female n = 14). The SEBQ was successfully translated and cross-culturally adapted into Danish. Three major modifications were made following the translation process and participant interviews. First, an introductory paragraph, including a recall period of the previous seven days, was added. Second, the administration of the questionnaire was changed from a paper to an electronic version. Finally, adaptations regarding semantic equivalence, especially concerning being ‘breathless’ and ‘short of breath’, were performed. The participants expressed that the final version of the SEBQ embraced their DB-related symptoms, was understandable, and easy to complete. The SEBQ is the first available Danish questionnaire to measure DB-related symptoms, following an internationally acknowledged cross-cultural adaptation and face validity evaluation approach. This promising validation should be followed by an assessment of measurement properties in individuals with DB-related symptoms to investigate the adequacy of the SEBQ in a Danish context.

Medically unexplained physical symptoms (MUPS) are symptoms without an identifiable organic cause that lead to functional impairment. MUPS is highly prevalent in general practice consultations. This pilot trial aimed to investigate the effectiveness and feasibility of a 5-week breathing retraining program focusing on basic anatomy and physiology, breathing awareness, nasal breathing and resonance (coherent) breathing for patients meeting the criteria for MUPS. The trial used a quantitative design with pre- and post-intervention measurements. Fifteen participants with MUPS and dysfunctional breathing (assessed by the Nijmegen Questionnaire) were recruited from two general practitioner offices. The intervention consisted of 5 weekly sessions including education on breathing physiology and weekly breathing exercises focused on nasal breathing and resonance breathing techniques. One week post intervention, improvements were observed in dysfunctional breathing scores, lower symptom severity, higher general well-being, and reduced musculoskeletal pain complaints. At 3 months post-intervention, sustained improvements were seen in dysfunctional breathing, general well-being, musculoskeletal pain, and additionally lower pseudoneurological, gastrointestinal, and allergy complaints, as well as lower overall symptom burden and improved end-tidal CO₂ levels. The trial concluded that the 5-week breathing program showed promising results for improving multiple patient-reported outcomes in MUPS. Recruitment, adherence, and acceptability of the program were satisfactory. A randomized controlled trial is recommended to further evaluate the efficacy of this breathing intervention for MUPS patients. Trial registration: ClinicalTrials.gov NCT06575920

Background/Objectives: Breathing efficiency and stability depend on the integrated function of biochemical, biomechanical, and psychophysiological processes across the unified upper and lower airway. Clinical interventions often address these domains in isolation, which may limit treatment outcomes. The primary objective of this article is to present Integrative Breathing Therapy (IBT) as a clinically applicable, multidimensional framework for training unified airway function. A secondary objective is to illustrate how this framework can inform clinical reasoning in orofacial myology and behavioural management of obstructive sleep apnea. Method: This article presents a clinical synthesis of physiological theory, neuroplasticity research, and applied breathing therapy to describe the theoretical and clinical foundations underpinning the Integrative Breathing Therapy (IBT) framework. Multidimensional phenotyping is used to organise dominant biochemical, biomechanical, and psychophysiological contributors to breathing inefficiency, with obstructive sleep apnea presented as a clinical example. Results: This synthesis outlines a unified airway model linking multidimensional phenotyping to targeted intervention selection. The IBT framework provides a structured approach for integrating biomechanical coordination, ventilatory control, and psychophysiological regulation within clinical practice. The obstructive sleep apnea exemplar demonstrates how phenotype-informed mapping can support clinical reasoning and guide individualised intervention strategies within OM and related behavioural approaches. Conclusions: Integrative Breathing Therapy offers a clinically grounded, multidimensional model for functional breathing optimisation that aligns unified airway training with principles of neural adaptation and systems-based clinical reasoning. This framework supports phenotype-guided clinical decision-making and provides a coherent structure for addressing breathing inefficiency and airway instability across a range of clinical populations, including those treated with orofacial myology and behavioural OSA therapies.

Purpose: Nasal disuse and mouth breathing are associated with negative structural, functional, postural, occlusal, and behavioural changes. While there is some research to suggest that nasal breathing exercises can reduce mouth breathing, clinical protocols have not been extensively investigated. The purpose of this research was to determine the feasibility and effectiveness of a nasal breathing rehabilitation protocol based on Integrative Breathing Therapy principles called Functional Nasal Breathing Rehabilitation (FNBR).