Technologies are essential for productive sectors to increase competitiveness and improve sustainable development. However, the technology benefits present a great delay in adoption in agricultural sectors, due to discrepancies between scientific research and local needs. This article presents a study for improving sustainability practices in the coffee supply chain, using emerging technologies, of two localities in the Frailesca region from Chiapas, Mexico, based on the current situation, expectations and actions expressed by 165 coffee producers and 12 representatives of two coffee producers’ organizations. Based on Mentzer theoretical support, the technology roadmaps, knowledge management and digital compass were used to draw coffee supply chain processes to identify concrete actions and explore technologies. The results show that the technological route must be focused on renewing and improving coffee quality, getting quality certifications and access to specialized markets. Digital quality management and advanced statistical process control seem to be the appropriate emerging technologies for enhancing the acquisition of resistant varieties, proper pest management, improvement in the collection of coffee beans, the right time and way to plant a coffee plant, soil analysis and for the management of weeds and water conservation and harvesting as sustainable practices in this region. In addition, statistical correlation showed that digital technologies can be better adopted, on average, by producers with 4–6 family members, aged between 40–44 years and without additional crops. The findings propose sustainable practices linked with emerging technologies, based on a technology roadmap and knowledge management methodologies for this region.

Currently, technology usage is a fundamental asset for creating, developing, and implementing innovations; however, these are not available to everyone, which is accentuated in women with agricultural occupations. The present study develops a proposal of technologies for mezcalilleras’ sustainability from Oaxaca, Mexico, based on a knowledge management methodology, through the application of questionnaires in face-to-face sessions, field visits, and statistical analysis to explore the imbalances enclosed in the agave–mezcal activity seen as its problems, failures, and barriers, as well as its correlation with the identified technological routes. The results reveal that a technological platform creation, the fabrication of fiber optic refractometer, a metal roof construction, the design of a horizontal distiller–fractionator, the employment of metal containers and production of glass bottles, and the generation of a software and an application, are the suitable technologies, according to the mezcalilleras’ requirements. This proposal can be important for academics, policymakers, and producers who wish to revitalize traditional knowledge of the small-scale sectors in Mexico through new ways of interaction with external agents and customers, new ways of production, and previous years’ production analysis.