Plasmonic nanoparticles (NPs) exhibit exceptional optical and electromagnetic (EM) properties that are, however, confined to their near–field region, limiting effective interactions with non-adsorbed species. Metal–organic frameworks (MOFs), renowned for their high surface area and tunable pores, provide an ideal complement through surface enrichment and subsequent molecular enrichment within their pores. The integration of plasmonic NPs with MOFs into nanohybrids overcomes this spatial constraint. This architectural synergy creates a synergistic effect, yielding properties superior to either component alone. This review summarizes recent advances in NP–MOF nanohybrids, with a focus on synthesis strategies for diverse architectures and their emergent functionalities. We highlight how this synergistic effect enables breakthrough applications in chemical sensing, cancer therapy, and catalysis. Finally, we conclude our discussion and present a critical outlook that explores the challenges and future opportunities in the design and applications of NP–MOF nanohybrids.