This paper examines the secrecy performance of a decode-and-forward (DF) relay-assisted device-to-device (D2D) communication system operating over Terahertz (THz) channels in multi-cluster two-wave (MTW) fading environments. Eavesdroppers are located near the relay and the receiver, intercepting their respective signals. Co-channel interference (CCI) affecting the relay, receiver, and eavesdroppers is also considered. To counter fading, both the relay and the receiver employ Maximal Ratio Combining (MRC). The analysis uses a characteristic function (CF)-based approach to derive key secrecy metrics, such as secrecy outage probability, secrecy success probability, the probability of strictly positive secrecy capacity, and intercept probability. The derived expressions are dependent on the characteristics of the THz, MTW fading, and CCI parameters. Finally, the system’s performance is then evaluated numerically for a range of channel and interference parameters.