Alveolar Osteitis (AO) is one of the most common complications of tooth extraction. Several therapeutic interventions have been described for the treatment of AO, however, there are no treatment standardized protocols. The aim of this study was to conduct a systematic review on the efficacy in pain control of the different treatments for AO. The feasibility of the application of these interventions is also discussed. A structured electronic and hand search strategy was applied to PubMed, Scopus, Cochrane Library, OpenGrey, and Google Scholar between January 2010 and July 2020 to identify studies according to PRISMA guidelines. The inclusion criteria were original English and Spanish clinical trials that analyzed pain-control parameters according to visual analog scale (VAS, 0-10 scale), or pain relief patients’ percentages. Those treatments that reach VAS ≤ 4 on day 2 or before; or ≥ 85% of patients with absence of pain symptoms at day 7 or before were considered accepTable for their recommendation. The final review included 17 clinical trials. Among them, there were analyzed a total of 39 different AO treatments. 53,8% of the treatments fulfill the proposed parameters for pain control. Treatment alternatives are multiple, heterogeneous, and difficult to compare. The management of AO is summarized in basic (intra-alveolar irrigation) and specific procedures (Alveogyl®, Neocones®, SaliCept Patch®, Low-Level Laser, Platelet-Rich Fibrin) that reach pain control success. They could be selected according to their availability and advantages or disadvantages. Key words:Dry socket, alveolar osteitis, treatment, management, pain control, pain relief.
22 November 2020 in Journal of Oral Pathology & Medicine
Objetivo: El schwannoma es un tumor neuroectodérmico benigno de la vaina nerviosa o vaina de mielina formada por células de Schwann. Aproximadamente entre el 25 y el 48% de los casos presentan localización en el territorio cervicofacial, especialmente en los tejidos blandos de esta región. Se los puede clasificar como schwannomas periféricos o intraóseos, éstos últimos también denominados centrales. Los schwannomas intraóseos son poco comunes, constituyen menos del 1% de los schwannomas presentes en la región en cuestión y menos del 0,2% de todos los tumores primarios óseos. El presente trabajo tiene como objetivo reportar un caso clínico de un schwannoma intraóseo mandibular, revisando aspectos clínicos, radiográficos y anatomopatológicos. El schwannoma intraóseo es una entidad poco común, o al menos se encuentra en una condición de subregistro en Argentina, por lo que este caso constituye una rareza. Caso clínico: Se presentó a la consulta una paciente de 30 años de edad, derivada al servicio de Cirugía y Traumatología Bucomaxilofacial del Hospital “Parmenio Piñero” de la Ciudad Autónoma de Buenos Aires por su odontólogo de cabecera, a raíz de un hallazgo radiográfico durante un control de rutina. Se planificó realizar una biopsia incisional, cuyo resultado anatomopatológico fue compatible con el diagnóstico de schwannoma intraóseo. Se procedió a realizar la enucleación completa. Finalmente, la paciente evolucionó sin complicaciones. Palabras clave: Intraóseo, nervioso, neurilenoma, schwannoma, tumor.
Objetive: The aim of this study is to describe Vitamin D3 levels in patients diagnosed with MRONJ from two centers in Argentina. Methods: A cross-sectional study was conducted on patients from two Oral Medicine centers in Argentina. Patients diagnosed with Medication-related osteonecrosis of the jaw between 2016 and 2022 were included. Vitamin D3 levels were measured in plasma. The STROBE guidelines for reporting cross-sectional studies were followed. Results: The final sample consisted of 53 individuals. Among them, 60.4% had oncological-based diseases while 39.6% were diagnosed with osteoporosis. Oncological patients with Medication-related osteonecrosis showed lower vitamin D3 levels (23.9 ng/mL) compared to the osteoporosis group (32.9 ng/mL) (p=0.03). Conclusion: These preliminary findings described the levels of vitamin D3 in patients diagnosed with MRONJ, highlighting the relevance of investigating the role of vitamin D3 and its clinical outcomes in these patients. Future research in this area could provide valuable insights for a comprehensive understanding of this role.