Anitha Nileshwar

Prof. Anitha Nileshwar

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Research Focus & Metrics

Academic Career Length

20Years (2007-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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21 June 2007 in British Journal of Anaesthesia
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ANAnitha Nileshwar
Anitha Nileshwar
ATA. Thudamaladinne
A. Thudamaladinne
Intubation of a patient with limited cervical spine movement or in whom movement of the cervical spine is not desirable is always a challenge even to the most experienced anaesthesiologist. The intubating laryngeal mask airway (ILMA) and the Bullard laryngoscope (BL) are two instruments recommended for endotracheal intubation of such patients. We compared their utility and safety in patients with simulated cervical spine immobility using manual inline stabilization (MILS). Sixty-two patients, ASA I or II, between 18 and 65 yr, were enrolled in this prospective and randomized study. They were randomly allocated to one of the two groups: Group BL (Bullard laryngoscope) and Group IL (Intubating Laryngeal Mask Airway). The patients were intubated orally using either equipment after induction of general anaesthesia. The success rate for intubation in the first or second attempt was higher in Group BL [90.32% (28/31)] than in Group IL [74.2% (23/31)] but was not statistically significant. The number of attempts taken for intubation and the total time to intubate were similar between the groups. Trauma as evidenced by blood on endotracheal tube or sore throat was similar in both groups. Both the BL and the ILMA are useful equipment in intubating patients with limitation of cervical movements. Although not statistically significant, the BL may provide a higher success rate of intubation when compared with the ILMA.

1 January 2019 in Journal of Anaesthesiology Clinical Pharmacology
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ANAnitha Nileshwar
Anitha Nileshwar
NGNeeraj Guttikonda
Neeraj Guttikonda
MRMadhu Rao
Madhu Rao
TSTk Sushma
Tk Sushma
Background and Aims: Preoperative laboratory testing is done to detect abnormalities in the body not detected by clinical examination. Often a battery of tests is advocated as a routine for patients scheduled for low or intermediate risk surgery. This prospective observational study was aimed to assess agreement of the current practice of preoperative laboratory investigations with the National Institute of Clinical Excellence (NICE) guidelines, and the impact of investigations on patient care and costs. Material and Methods: The study was conducted at a tertiary referral center on 385 patients aged 18-70 years of either gender, posted for elective general surgical, gynaecological or otolaryngological surgery. Sixteen investigations were examined: hemogram, blood urea, serum creatinine, serum electrolytes, coagulation profile, urinalysis, thyroid function tests, electrocardiogram, echocardiogram, chest x-ray, pulmonary function tests, blood sugar, glycosylated hemoglobin, liver function tests, treadmill test and coronary angiogram. The history and physical examination were reviewed to examine for indication for these laboratory investigations. These were compared with NICE guidelines. Impact of these investigations on anesthetic decision-making was noted. Results: There was almost no agreement of the current practice with the NICE guidelines. The total cost of all tests obtained was Rs 5,48,755. Total additional cost of unindicated tests was Rs 5,10,730 (93%). Average amount spent on additional investigations per patient was Rs 1326.57. Conclusion: Most investigations are overprescribed and have minimal agreement with NICE guidelines. None of the tests had any impact on clinical care. Nearly a million rupees is incurred per year in one referral hospital alone, when NICE guidelines are not followed.


29 November 2019 in Anesthesiology Research and Practice
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PSPrabhu P. Sujatha
Prabhu P. Sujatha
ANAnitha Nileshwar
Anitha Nileshwar
HKH. M. Krishna
H. M. Krishna
SPS. S. Prasad
S. S. Prasad
MPManjunath Prabhu
Manjunath Prabhu
SKShobha U. Kamath
Shobha U. Kamath
Introduction. Optimum perioperative fluid therapy is important to improve the outcome of the surgical patient. This study prospectively compared goal-directed intraoperative fluid therapy with traditional fluid therapy in general surgical patients undergoing open major bowel surgery. Methodology. Patients between 20 and 70 years of age, either gender, ASA I and II, and scheduled for elective open major bowel surgery were included in the study. Patients who underwent laparoscopic and other surgeries were excluded. After routine induction of general anaesthesia, the patients were randomised to either the control group (traditional fluid therapy), the FloTrac group (based on stroke volume variation), or the PVI group (based on pleth variability index). Fluid input and output, recovery characteristics, and complications were noted. Results. 306 patients, with 102 in each group, were enrolled. Five patients (control (1), FloTrac (2), and PVI (2)) were inoperable and were excluded. Demographic data, ASA PS, anaesthetic technique, duration of surgery, and surgical procedures were comparable. The control group received significantly more crystalloids (3200 ml) than the FloTrac (2000 ml) and PVI groups (1875 ml), whereas infusion of colloids was higher in the FloTrac (400–700 ml) and PVI (200–500 ml) groups than in the control group (0–500 ml). The control group had significantly positive net fluid balance intraoperatively (2500 ml, 9 ml/kg/h) compared to the FloTrac (1515 ml, 5.4 ml/kg/h) and PVI (1420 ml, 6 ml/kg/h) groups. Days to ICU stay, HDU stay, return of bowel movement, oral intake, morbidity, duration of hospital stay, and survival rate were comparable. The total number of complications was not different between the three groups. Anastomotic leaks occurred more often in the Control group than in the others, but the numbers were small. Conclusions. Use of goal-directed fluid management, either with FloTrac or pleth variability index results in a lower volume infusion and lower net fluid balance. However, the complication rate is similar to that of traditional fluid therapy. This trial is registered with CTRI/2018/04/013016.

1 January 2020 in Annals of Cardiac Anaesthesia
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ANAnitha Nileshwar
Anitha Nileshwar
VKVogireddy R Krishna
Vogireddy R Krishna
NPNitin Patil
Nitin Patil
Introduction: Off-pump coronary artery bypass (OPCAB) surgery is associated with evasion of complications of cardiac bypass. The incidence of postoperative atrial fibrillation (POAF) may also be reduced because of less ischemia and inflammation. Aim: Prospective evaluation of utility of CHA2DS2-VASc score in the prediction of POAF after OPCAB surgery. Methodology: In this prospective, observational study, 99 patients who underwent elective isolated OPCAB surgery were included. Patients with pacemaker in situ, receiving antiarrhythmic drugs preoperatively, and preexisting atrial fibrillation were excluded. A detailed history taking and physical examination were done preoperatively and the CHA2DS2-VASc scores were calculated for each patient. They received a standard anesthetic including midazolam, fentanyl, propofol, vecuronium, and isoflurane. The number of grafts, inotrope usage, and blood product transfusion in the perioperative period were noted. Patients were followed up for 5 days after surgery for development of new onset POAF requiring treatment. Results: About 20 of the 99 patients developed POAF. POAF occurred most commonly on postoperative day 2. They were older, more likely diabetic, had preoperative diastolic dysfunction, and received blood products perioperatively. POAF group had higher mean CHA2DS2-VASc score (3.6 ± 0.821 vs. 2.11 ± 1.35) and had longer hospital stay (16.85 ± 8.61 vs. 12.6 ± 4.05 days) than no POAF group. The cutoff for CHA2DS2-VASc score was 3, which showed 90% sensitivity, 77.22% specificity, 50% positive predictive value, and 96.63% negative predictive value. Conclusions: CHA2DS2-VASc score is useful in predicting POAF after OPCAB surgery. Higher the CHA2DS2-VASc score, greater is the possibility of development of POAF.

1 January 2017 in Indian Journal of Respiratory Care
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ASAnitha Shenoy
Anitha Shenoy
PNPawan Nanjangud
Pawan Nanjangud
ANAnitha Nileshwar
Anitha Nileshwar
Indian Journal of Respiratory Care, India