Positive dimension, reflecting "the pleasure you derive from being able to do your work well. For example, you may feel like it is a pleasure to help others through your work. You may feel positively about your colleagues or your ability to contribute to the work setting or even the greater good of society". Compassion Fatigue (CF) represents the negative dimension of professional quality of life. It, in turn, includes two subdomains: Burnout (BO) and Secondary Traumatic Stress (STS). Burnout is characterized by chronic emotional and physical exhaustion, frustration, and a sense of inefficacy, often resulting from prolonged exposure to demanding work environments. It typically develops gradually and is associated with feelings of hopelessness, decreased job performance, and the perception that one's efforts are futile. Contributing factors may include excessive workload, lack of support, and organizational stressors. Secondary Traumatic Stress, on the other hand, refers to the emotional distress that arises from indirect exposure to traumatic experiences through one's work with affected individuals. STS symptoms may include intrusive thoughts, sleep disturbances, hypervigilance, and avoidance behaviors related to the trauma encountered by those being helped (Stamm, 2005)." Using the Professional Quality of Life (ProQOL), Su and colleagues (2021) conducted a large-scale study into hospital staff in Taiwan, and found moderate levels of burnout (mean: 24.9), low levels of compassion fatigue (CF) (mean score: 20.9) but moderate levels of compassion satisfaction (CS) (mean score: 32). Perhaps, as some authors have proposed, a sense of purpose and of undertaking a shared mission could increase CS and possibly protect HCWs from lasting distress (Dwyer et al., 2021). Therefore compassion satisfaction could represent a protective factor in reducing stress and depression, as confirmed in other findings (Ruiz-Fernandez et al.,

Background: Cancer survivors frequently experience persistent physical and psychological sequelae, including impaired physical function, fatigue, anxiety/depressive symptoms, and reduced health-related quality of life (HRQoL). Exercise is an effective non-pharmacological intervention; however, comparative evidence between multicomponent training (MCT) and aerobic training (AT) using a multidomain framework remains limited. Methods: In this randomized controlled parallel-group trial, 47 cancer survivors (mean age 63.0 ± 8.9 years) were allocated to a 24-week supervised MCT programme (n = 16), an AT programme (n = 16), or a non-exercise control group (CG; n = 15). Outcomes were assessed at baseline and post-intervention including body composition (BIA), physical performance, fatigue (FSS), anxiety (STAI-Y1/Y2), depressive symptoms (BDI), and HRQoL (EORTC QLQ-C30). Results: Fat mass decreased in both MCT (p = 0.005) and AT (p = 0.034), whereas arm circumference increased only in MCT (p < 0.001). Significant Group × Time interactions were observed for major physical performance outcomes; improvements were broader in MCT, while AT showed its largest change in aerobic endurance. Between-group contrasts indicated greater gains with MCT than AT for chair-stand (p = 0.046), sit-and-reach (p = 0.048), and handgrip strength (p = 0.049). Significant interaction effects were also observed for fatigue and psychological outcomes (FSS: p = 0.003; STAI-Y1 and STAI-Y2: p < 0.001; BDI: p < 0.001) and for HRQoL global health (p = 0.003), with larger improvements in MCT than AT for fatigue, state anxiety, and depressive symptoms (all p < 0.05), but not for trait anxiety (p > 0.05). Conclusions: A 24-week supervised MCT programme produced broader benefits than AT alone across physical function and selected psychological outcomes in cancer survivors. These findings support the incorporation of multicomponent exercise into survivorship care as a feasible and effective strategy for addressing multidimensional treatment sequelae.