The green synthesis of bimetallic nanoparticles using plant extracts is attracting an increasing attention in the nanoparticle production field since, besides being available for the production of bimetallic nanoparticles, it is cost-effective, eco-friendly, and it is available for large scale production. The required agents to reduce and stabilize metal nanoparticles during synthesis already exist in plant extracts as phytochemicals. The study highlights the synthesis of gold, silver, and silver-gold (bimetallic) nanoparticles at room temperature using an aqueous extract of dried bay leaves and their physical and chemical characterizations for their potential applications. We have synthesized Ag, Au, and Ag-Au nanoparticles using the aqueous bay leaves extract. The nanoparticles were characterized by UV-Vis spectroscopy, X-ray diffraction (XRD), transmission electron microscopy (TEM), and Fourier transform infrared spectroscopy (FT-IR). According to UV-Vis spectroscopic results, it is concluded that Ag-Au bimetallic nanoparticles synthesized in the extract have a core-shell arrangement. XRD measurements revealed that all nanoparticles (Ag, Au, and Ag-Au) are in fcc structure. The nanoparticles' average sizes were measured as 10±7, 23±4, and 8±3 nm for Ag, Au, and Ag-Au nanoparticles, respectively, as determined from the TEM images. The results offer that besides Ag and Au nanoparticles, bimetallic Ag-Au nanoparticles synthesized in an aqueous extract of dried bay leaves may play a prominent role in the field of nanotechnology, especially in nanomedicine.

Objectives: The study aimed to evaluate the frequency of juvenile fibromyalgia syndrome (JFMS) in patients diagnosed with juvenile idiopathic arthritis (JIA) and familial Mediterranean fever (FMF) with joint symptoms and compare them with a healthy control group. Patients and methods: This retrospective study was conducted with 181 participants between January and April 2023. One hundred twenty-one patients with JIA or FMF diagnoses (71 females, 50 males; mean age: 15.6±2.1 years; range, 12 to 23 years) and 60 healthy individuals (36 females, 24 males; mean age: 14.5±1.6 years; range, 12 to 17 years) were included in the patient group and the control group, respectively. The pain and symptom assessment scale was applied for the JFMS diagnosis, and the output data were analyzed with the widespread pain index and symptom severity scale. Results: Of the patient group, 57% (n=69) were diagnosed with FMF, and 43% (n=52) were diagnosed with JIA. When the two groups were compared with those diagnosed with JFMS, statistical significance was detected (p

Amaç: Psoriatik Artrit (PsA), sedef hastalığı (PsO) olan hastaların %10-30'unu etkileyen kronik ilerleyici inflamatuar bir hastalıktır. "PsA Sine sedef hastalığı" terimi, "cilt belirtileri olmadan PsA teşhisi konan hastaları" tanımlamak için kullanılır. Bu çalışmada “PsA” “sine psoriasis”in demografik ve klinik özelliklerinin CASPAR kriterlerine göre tanımlanması amaçlandı. Hastalar ve Yöntem: 2016-2022 yılları arasında CASPAR kriterlerine göre PsA sine psoriasis tanısı alan 29 hasta çalışmaya dahil edildi. Romatizmal hastalığı ve herhangi bir cilt tutulumu olan hastalar çalışma dışı bırakıldı. Bulgular: Çalışmaya dahil edilen 29 hastanın tamamına CASPAR kriterlerine göre PsA tanısı konuldu. Hastaların 16'sı kadındı. Hastaların ortalama (±SS) yaşı 45±11 idi. Hastaların ortalama (±SD) PsA süresi 6,2±3,0 yıldı. PsA'lı hastaların birinci derece akrabalarında psoriazis öyküsü %54,1; ikinci derece akrabalarında psöriazis öyküsü ise %45,9 olarak saptandı. Hastaların %39,4'ünde poliartiküler, %35,7'sinde oligoartiküler, %24,9'unda aksiyal tutulum vardı. Tüm hastaların 19'unda (%65,5) DİP tutulumu mevcuttu. Hastaların %88.9'unda tırnak bulguları mevcuttu. Ayrıca hastaların 17'sinde (%58,6) entezit, 18'inde (%62) daktilit saptandı. Sonuç: PsA'yı düşündüren klinik semptom ve bulguları olan ve ailede psöriazis öyküsü olan hastalar, PsA sine psoriasisi olarak sınıflandırılabilir. Daktilit ve DIP artritli hastalar, ailesel sedef hastalığı PsA'nın bir alt grubunu temsil edebilir.