Biomedical materials constitute a vast scientific research field, which is devoted to producing medical devices which aid in enhancing human life. In this field, there is an enormous demand for long-lasting implants and bone substitutes that avoid rejection issues whilst providing favourable bioactivity, osteoconductivity and robust mechanical properties. Hydroxyapatite (HAp)-based biomaterials possess a close chemical resemblance to the mineral phase of bone, which give rise to their excellent biocompatibility, so allowing for them to serve the purpose of a bone-substituting and osteoconductive scaffold. The biodegradability of HAp is low (Ksp ≈ 6.62 × 10⁻¹²⁶) as compared to other calcium phosphates materials, however they are known for their ability to develop bone-like apatite coatings on their surface for enhanced bone bonding. Despite its favourable bone regeneration properties, restrictions on the use of pure HAp ceramics in high load-bearing applications exist due to its inherently low mechanical properties (including low strength and fracture toughness, and poor wear resistance). Recent innovations in the field of bio-composites and nanoscience have reignited the investigation of utilising different carbonaceous materials for enhancing the mechanical properties of composites, including HAp-based bio-composites. Researchers have preferred carbonaceous materials with hydroxyapatite due to their inherent biocompatibility and good structural properties. It has been demonstrated that different structures of carbonaceous material can be used to improve the fracture toughness of HAp, as they can easily serve the purpose of being a second phase reinforcement, with the resulting composite still being a biocompatible material. Nanostructured carbonaceous structures, especially those in the form of fibres and sheets, were found to be very effective in increasing the fracture toughness values of HAp. Minor addition of CNTs (3 wt.%) has resulted in a more than 200% increase in fracture toughness of hydroxyapatite-nanorods/CNTs made using spark plasma sintering. This paper presents a current review of the research field of using different carbonaceous materials composited with hydroxyapatite with the intent being to produce high performance biomedically targeted materials.

This review focuses on the recent advances in the lesser-studied microemulsion synthesis methodologies of the following noble metal colloid systems (i.e., Os, Re, Ir, and Rh) using either a normal or reverse micelle templating system. The aim is to demonstrate the utility and potential of using this microemulsion-based approach to synthesize these noble metal nanoparticle systems. Firstly, some fundamentals and important factors of the microemulsion synthesis methodology are introduced. Afterward, a review of the investigations on the microemulsion syntheses of Os, Re, Ir, and Rh nanoparticle (NP) systems (in all forms, viz., metallic, oxide, mixed-metal, and discrete molecular complexes) is presented for work published in the last ten years. The chosen noble metals are traditionally very reactive in nanosized dimensions and have a strong tendency to aggregate when prepared via other methods. Also, the particle size and particle size distribution of these colloids can have a significant impact on their catalytic performance. It is shown that the microemulsion approach has the capability to better stabilize these metal colloids and can control the size of the synthesized NPs. This generally leads to smaller particles and higher catalytic activity when they are tested in applications.