Matthias Maak

Dr. Matthias Maak

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Research Focus & Metrics

Academic Career Length

10Years (2017-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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15 October 2018 in Surgical Endoscopy
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CSChristoph Werner Strey
Christoph Werner Strey
CWChristoph Wullstein
Christoph Wullstein
MAMichel Adamina
Michel Adamina
AAAyman Agha
Ayman Agha
HAHeiko Aselmann
Heiko Aselmann
SBStefan Benz
Stefan Benz
Background Complete mesocolic excision is gradually becoming an established oncologic surgical principle for right hemicolectomy. However, the procedure is technically demanding and carries the risk of serious complications, especially when performed laparoscopically. A standardized procedure that minimizes technical hazards and facilitates teaching is, therefore, highly desirable. Methods An expert group of surgeons and one anatomist met three times. The initial aim was to achieve consensus about the surgical anatomy before agreeing on a sequence for dissection in laparoscopic CME. This proposal was evaluated and discussed in an anatomy workshop using post-mortem body donors along with videos of process-informed procedures, leading to a definite consensus. Results In order to provide a clear picture of the surgical anatomy, the “open book” model was developed, consisting of symbolic pages representing the corresponding dissection planes (retroperitoneal, ileocolic, transverse mesocolic, and mesogastric), vascular relations, and radicality criteria. The description of the procedure is based on eight preparative milestones, which all serve as critical views of safety. The chosen sequence of the milestones was designed to maximize control during central vascular dissection. Failure to reach any of the critical views should alert the surgeon to a possible incorrect dissection and to consider converting to an open procedure. Conclusion Combining the open-book anatomical model with a clearly structured dissection sequence, using critical views as safety checkpoints, may provide a safe and efficient platform for teaching laparoscopic right hemicolectomy with CME.

28 January 2023 in European Journal of Trauma and Emergency Surgery
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BLBruno Leonardo Bancke Laverde
Bruno Leonardo Bancke Laverde
MMMatthias Maak
Matthias Maak
MLMelanie Langheinrich
Melanie Langheinrich
SKStephan Kersting
Stephan Kersting
ADAxel Denz
Axel Denz
MBMaximilian Brunner
Maximilian Brunner
Purpose: The aim of the present study was to identify risk factors associated with postoperative morbidity and major morbidity, with a prolonged length of hospital stay and with the need of readmission in patients undergoing appendectomy due to acute appendicitis. Methods: We performed a retrospective analysis of 1638 adult patients who underwent emergency appendectomy for preoperatively suspected acute appendicitis from 2010 to 2020 at the University Hospital Erlangen. Data including patient demographics, pre-, intra-, and postoperative findings were collected and compared between different outcome groups (morbidity, major morbidity, prolonged length of postoperative hospital stay (LOS) and readmission) from those patients with verified acute appendicitis (n = 1570). Results: Rate of negative appendectomies was 4%. In patients with verified acute appendicitis, morbidity, major morbidity and readmission occurred in 6%, 3% and 2%, respectively. Mean LOS was 3.9 days. Independent risk factors for morbidity were higher age, higher preoperative WBC-count and CRP, lower preoperative hemoglobin, longer time to surgery and longer duration of surgery. As independent risk factors for major morbidity could be identified higher age, higher preoperative CRP, lower preoperative hemoglobin and longer time to surgery. Eight parameters were independent risk factors for a prolonged LOS: higher age, higher preoperative WBC-count and CRP, lower preoperative hemoglobin, need for conversion, longer surgery duration, presence of intraoperative complicated appendicitis and of postoperative morbidity. Presence of malignancy and higher preoperative WBC-count were independent risk factors for readmission. Conclusion: Among patients undergoing appendectomy for acute appendicitis, there are relevant risk factors predicting postoperative complications, prolonged hospital stays and readmission. Patients with the presence of the identified risk factors should receive special attention in the postoperative course and may benefit from a more individualized therapy.

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BLBruno Leonardo Bancke Laverde
Bruno Leonardo Bancke Laverde
MMMatthias Maak
Matthias Maak
MLMelanie Langheinrich
Melanie Langheinrich
SKStephan Kersting
Stephan Kersting
ADAxel Denz
Axel Denz
MBMaximilian Brunner
Maximilian Brunner
(1) Background: Since its introduction in the 1990s, laparoscopic appendectomy has become established over the years and is today considered the standard therapy for acute appendicitis. In some cases, however, a conversion to the open approach is still necessary. The primary aim of this study was to identify risk factors for the need to convert from the laparoscopic to an open approach during appendectomy for acute appendicitis. (2) Methods: A retrospective analysis of 1220 adult patients who underwent laparoscopic appendectomy for acute appendicitis from 2010 to 2020 at the University Hospital Erlangen was performed. Data, including patient demographics and pre-, intra-, and postoperative findings, were collected and compared between patients with and without conversion. (3) Results: The conversion rate in our cohort was 5.5%. A higher preoperative WBC count and CRP (OR 1.9, p = 0.042, and OR 2.3, p = 0.019, respectively), as well as the presence of intraoperative perforation, necrosis or gangrene, perityphlitic abscess and peritonitis (OR 3.2, p = 0.001; OR 2.3, p = 0.023; OR 2.6, p = 0.006 and OR 2.0, p = 0.025, respectively) were identified as independent risk factors for conversion from the laparoscopic to the open approach. Conversion was again independently associated with higher morbidity (OR 2.2, p = 0.043). (4) Conclusion: The laparoscopic approach is feasible and safe in the majority of patients with acute appendicitis. Only increased inflammatory blood markers could be detected as the preoperative risk factors potentially influencing the choice of surgical approach but only with low specificity and sensitivity. For the decision to convert, intraoperative findings are additionally crucial. However, patients with conversion should receive special attention in the postoperative course, as these have an increased risk of developing complications.

28 March 2025 in Turkish Journal of Surgery
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Journal Article
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MMMatthias Maak
Matthias Maak
PMPhilipp Mörsdorf
Philipp Mörsdorf
LBLayla Bari
Layla Bari
Myriam Braun-MünkerMyriam Braun-Münker
Myriam Braun-Münker
MSMaximilian Scharonow
Maximilian Scharonow
Dietrich DollDietrich Doll
Dietrich Doll
Intergluteal fold depth has no influence on pilonidal sinus disease development - Turkish Journal of Surgery

22 November 2023 in International Journal of Colorectal Disease
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Journal Article
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BLBruno Leonardo Bancke Laverde
Bruno Leonardo Bancke Laverde
MMMatthias Maak
Matthias Maak
MLMelanie Langheinrich
Melanie Langheinrich
SKStephan Kersting
Stephan Kersting
ADAxel Denz
Axel Denz
MBMaximilian Brunner
Maximilian Brunner
Introduction: Bacteria play an important role not only in pathogenesis of appendicitis but also in the postoperative course of patients. However, the usefulness of an intraoperative swab during appendectomy is controversial. The primary aim of this study was to investigate the impact of intraoperative swab during appendectomy on the postoperative outcome in patients with uncomplicated and complicated appendicitis. Methods: A retrospective analysis was conducted on a consecutive series of 1570 adult patients who underwent appendectomy for acute appendicitis at the University Hospital Erlangen between 2010 and 2020. Data regarding the intraoperative swab were collected and analyzed for the entire cohort as well as for patients with uncomplicated and complicated appendicitis. Results: An intraoperative swab was taken in 29% of the cohort. The bacterial isolation rate in the obtained intraoperative swabs was 51%, with a significantly higher rate observed in patients with complicated appendicitis compared to those with uncomplicated appendicitis (79% vs. 35%, p < 0.001). The presence of a positive swab was significantly associated with worse postoperative outcomes, including higher morbidity, increased need for re-surgery, and longer hospital stay, when compared to patients without a swab or with a negative swab. A positive swab was an independent risk factor for postoperative morbidity (OR 9.9 (95% CI 1.2–81.9), p = 0.034) and the need for adjustment of postoperative antibiotic therapy (OR 8.8 (95% CI 1.1–72.5), p = 0.043). However, a positive swab resulted in postoperative antibiotic therapy adjustment in only 8% of the patients with bacterial isolation in the swab. Conclusion: The analysis of swab samples obtained during appendectomy for acute appendicitis can help identify patients at a higher risk of a worse postoperative outcome. However, the frequency of antibiotic regime changes based on the swab analysis is low.

16 April 2024 in coloproctology
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DDDietrich Doll
Dietrich Doll
HEHelge Ernst
Helge Ernst
LHLars-Patrick Hall
Lars-Patrick Hall
MOMarcel Orth
Marcel Orth
Myriam Braun-MünkerMyriam Braun-Münker
Myriam Braun-Münker
MMMatthias Maak
Matthias Maak
Background: Mounting evidence links cut occipital hair fragments to the formation of pilonidal sinus disease (PSD). Anatomical variations in the shape of the dorsal crest between the occiput and the upper intergluteal fold may be crucial in the downward movement of hair to the glabella sacralis region. Objective: This study aims to investigate the shape and height of the glabellar cushion and their potential influence on the development of PSD. Patients and methods: We established a method for capturing the shape of the thoracolumbar back down to the intragluteal fold using a structured light 3D scanning device. The soft tissue surface contour of this region was measured. We developed algorithms to extract the width and shape of the canal between the erector trunci, as well as the height of the glabellar cushion. Included were 155 individuals, 94 PSD patients and 61 without PSD. Results: Glabellar height differs significantly between PSD and non-PSD cohorts. In total, PSD was associated with a 7.8 ± 3.7 mm glabellar cushion, while non-PSD patients exhibited a 9.7 ± 3.8 mm glabellar cushion (p = 0.0021). In male PSD patients, the glabellar height was 7.8 ± 3.7 mm (mean ± SD), while in female PSD patients it was 7.7 ± 3.6 mm. Conversely, non-PSD males had a glabellar cushion height of 8.9 ± 2.7 mm, and non-PSD females of 10.5 ± 4.4 mm. Conclusion: A higher glabellar region is associated with a lower incidence of pilonidal sinus disease. Therefore, elevating and bolstering the glabellar region could be beneficial for preventing recurrence.