Background/Objectives: Portal vein thrombosis (PVT) is a clinically significant condition in which early risk stratification remains challenging, particularly in emergency settings where rapid decision-making is required. This study aimed to evaluate the prognostic value of the Systemic Immune-Inflammation Index (SII), Systemic Inflammation Response Index (SIRI), and the Model for End-Stage Liver Disease (MELD) score in predicting the need for intensive care in patients with PVT. Methods: A retrospective analysis was conducted on adult patients (>18 years) diagnosed with PVT in the emergency department between January 2018 and December 2024. A total of 29 patients meeting the inclusion and exclusion criteria were included. Demographic characteristics, laboratory parameters, Intensive Care Unit (ICU) admission status, and 90-day mortality were analyzed. The sensitivity and specificity of MELD, SII, and SIRI for predicting ICU admission were calculated. Non-normally distributed variables were expressed as median (interquartile range, IQR) and compared using the Mann–Whitney U test. Results: The mean age of patients was 60.5 ± 16.2 years, and 18/29 (62.1%) were male. ICU admission was required in 9/29 (31.0%) of cases. MELD score (median 18.7 [11.0–21.9] vs. 7.9 [6.7–13.5], p = 0.003), bilirubin (median 2.4 [1.0–4.2] vs. 0.7 [0.4–1.1], p = 0.016), and SIRI (median 6.4 [2.3–21.3] vs. 1.4 [0.6–9.3], p = 0.038) were significantly higher in ICU-admitted patients. MELD score showed 66.7% sensitivity and 95% specificity, while SIRI had 88.9% sensitivity and 55% specificity for ICU prediction. Conclusions: MELD score, bilirubin, and SIRI are significantly associated with ICU admission in PVT patients. Their integration into emergency department protocols may assist in early risk stratification and resource allocation.
AimWe aimed to evaluate the diagnostic value of hemogram-based inflammatory parameters particularly leukocyte, leukocyte-to-platelet ratio, and neutrophil-to-platelet ratio in identifying myocardial infarction among patients presenting to the emergency department with chest pain.Materials and Methods:A total of 60 myocardial infarction and 60 non- myocardial infarction patients aged over 18 years who presented to the emergency department with chest pain between January and February 2025 were retrospectively analyzed. Hemogram, biochemistry, electrocardiography, and creatine kinase-MB values were evaluated. leukocyte, , leukocyte-to-platelet and neutrophil-to-platelet ratios were compared between the two groups. The discriminatory performance of these parameters was assessed using Receiver Operating Characteristic analysis, and optimal cutoff values were determined using the Youden index.Results:Glucose, creatine kinase-MB, leukocyte, neutrophil count leukocyte-to-platelet ratio, and neutrophil-to-platelet ratio levels were significantly higher in the myocardial infarction group compared with the control group (p
Acute ischemic stroke is one of the leading causes of morbidity and mortality in adults. Although intravenous thrombolytic therapy (IVTT) can improve neuro
20 October 2026 in Eurasian Journal of Emergency Medicine
Comparison of Clinical, Laboratory, and Inflammatory Parameters in Pediatric Upper and Lower Gastrointestinal Bleeding - Eurasian Journal of Emergency Medicine
31 December 2025 in Eurasian Journal of Critical Care
Introduction: Aortic dissection is critical, and recent studies increasingly highlight the prognostic value of laboratory parameters alongside diagnostic CT angiography. Materials and Methods: This study included 23 adult patients diagnosed with aortic dissection between January 2023 and January 2025, analyzing the association between admission lab data, derived scores, and outcomes like mortality and ICU stay. Results: Neutrophil count was found to be significantly higher in patients who died (p = 0.03), with 57.1% sensitivity and 68.8% specificity in predicting mortality. A significant negative correlation was found between HALP score and ICU length of stay (r = –0.471, p = 0.023), whereas CRP levels were positively correlated with ICU stay duration (r = 0.504, p = 0.014). Conclusion: Neutrophil count, HALP score, and CRP levels may serve as useful biomarkers for predicting the prognosis of aortic dissection and aiding early risk stratification
19 August 2024 in European Journal of Therapeutics
Objective: We aimed to investigate the anxiety effect of working conditions on intern doctors in emergency department (ED), the severity of this effect according to the Beck Anxiety Inventory (BAI), and the hormonal factors involved in the etiology of anxiety. Methods: A prospective analysis was conducted on a group of 74 intern doctors who completed training in the ED between May and October 2017. Participants were asked to complete the BAI form and have their blood samples taken at 07:00 a.m. during both the first and last night shifts. The blood samples have been utilized in the study of Adrenocorticotropic Hormone (ACTH), Atrial Natriuretic Peptide (ANP) and Cholecystokinin (CCK), hormones that have been found to have a strong correlation with stress levels. A comparison of hormone levels and BAI scores was conducted before and after the internship to assess any changes. Results: The sample size for the study consisted of seventy-four interns, of which 47.3% (n=35) were identified as male. The average age was 25 +/- 2 years. No significant difference was detected in ACTH levels before and after the internship (p = 0.087), although the end-of-internship BAI score and ANP and CCK levels were found to be significantly higher in the entire group (p=0.001, p=0.001, p=0.048; respectively). While the post-internship BAI score and ANP levels were significantly higher in males (p=0.001, p=0.015, respectively), no significant difference was detected in the ACTH and CCK levels before and after the internship (p=0.128, p=0.077, respectively). While post-internship BAI score, ACTH and ANP levels were found to be significantly higher in female (p=0.001, p=0.026, p=0.001; respectively); No significant difference was detected in CCK levels (p = 0.155). Conclusion: Emergency departments are places where stress and anxiety are intensely experienced. The post-internship hormone levels reveal a predominantly anxiolytic pattern (with no notable alteration in ACTH levels but a rise in ANP), while the elevated BAI score can be attributed to the subjective nature of this assessment tool. Identifying the hormones that increase or decrease in response to stress and conducting further research on treatment may be one method of coping with stress.