Chronic diabetic wounds are a serious complication of diabetes and often result in limb amputations and confer high mortality rates. The proinflammatory secretome in the wound perpetuates defective neovascularization and contributes to dysregulated tissue repair. This study aims to design a gelatin methacrylamide (GelMA) hydrogel to sustained the release of grancalcin‐neutralizing antibody (GCA‐NAb) and evaluate it as a potential scaffold to promote diabetic wound healing. Results show that the expression of grancalcin(GCA), a protein secreted by bone marrow‐derived immune cells, is elevated in the wound sites of individuals and animals with diabetic ulcers. Genetic inhibition of grancalcin expression accelerates vascularization and healing in an animal model. Mechanistic studies show that grancalcin binds to transient receptor potential melastatin 8(TRPM8) and partially inactivates its downstream signaling pathways, thereby impairing angiogenesis in vitro and ex vivo. Systemic or topical administration of a GCA‐NAb accelerate wound repair in mice with diabetes. The data suggest that GCA is a potential therapeutic target for the treatment of diabetic ulcers.

Perovskite solar cells (PSCs) have attracted considerable research interest in recent decades due to their remarkable power conversion efficiencies. However, their thermal stability remains one of the crucial challenges for commercial applications. Bathocuproine (BCP), widely employed as an interfacial buffer layer between the electron transport layer and the metal electrode, tends to undergo thermal aggregation at elevated temperatures, thereby compromising device stability. In this paper, the aggregation behavior of BCP under thermal stability testing was investigated. It was proposed that introducing polyethylenimine ethoxylated (PEIE) into BCP could inhibit its high-temperature aggregation. The –NH and –OH groups in PEIE can form hydrogen bonds with the pyridine nitrogen in BCP. This interaction enables moderate π–π stacking to persist over a broader temperature range, thereby improving morphology and uniformity of the film. Concurrently, PEIE optimizes energy level alignment at the C₆₀/BCP interface, facilitating more efficient electron extraction and transport. Moreover, the incorporation of PEIE remarkably suppresses the infiltration of Ag ions under continuous thermal conditions, which further enhances the thermal stability of the device. By utilizing the PEIE-modified BCP buffer layer, the resulting PSCs demonstrate a champion power conversion efficiency (PCE) of 25.81%. Even after 1000 hours of operation under a relative humidity of 30%, they still retain an efficiency of more than 85%, demonstrating significantly enhanced stability. This work presents an innovative design strategy for developing PSCs with simultaneously enhanced efficiency and operational stability.