Chilan B. G. Leite

Dr. Chilan B. G. Leite


Research Focus & Metrics

Academic Career Length

10Years (2017-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 January 2021 in Orthopaedic Journal of Sports Medicine
Verified
Journal Article
Open access
PDF file
CLChilan B. G. Leite
Chilan B. G. Leite
TSTársis P. Santos
Társis P. Santos
PGPedro N. Giglio
Pedro N. Giglio
JPJosé R. Pécora
José R. Pécora
GCGilberto L. Camanho
Gilberto L. Camanho
RGRiccardo G. Gobbi
Riccardo G. Gobbi
Tibial tubercle osteotomy with concomitant distalization for the treatment of patellar instability remains controversial, as it may cause anterior knee pain and chondral degeneration. To evaluate radiographic, clinical, and functional outcomes in patients who had patellar instability with patella alta and underwent tibial tubercle osteotomy with distalization (TTO-d) as well as medial patellofemoral ligament reconstruction. Case series; Level of evidence, 4. Included in this study were 25 patients (31 cases) (mean age at surgery, 28.7 years; range, 14-33 years) with patellar instability and patella alta who underwent TTO-d with minimum 1-year follow-up. The Caton-Deschamps index (CDI), tibial tubercle–trochlear groove (TT-TG) distance, and amount of distalization were assessed. Clinical and functional variables included J-sign, anterior knee pain, apprehension test, Tegner activity level, and Kujala score. The mean follow-up period was 2.62 years. The mean TT-TG was 16.15 mm (range, 7-24 mm); the mean CDI changed from 1.37 (1.25-1.7) preoperatively to 1.02 (0.9-1.12) postoperatively (P = .001); and the mean amount of tibial tubercle distalization was 8.80 mm (range, 4-16 mm). Lateral release (22 cases; 71.0%), medialization of tibial tubercle (17 cases; 54.8%), and autologous chondrocyte implantation (4 cases; 12.9%) were other associated procedures. The J-sign improved in 30 cases (96.8%; P = .001), and there was a complete resolution of anterior knee pain in 22 cases (71.0%; P = .001). An exploratory analysis showed that patellar cartilage defect severity was correlated with persistent pain (P = .005). The apprehension test became negative in all cases (P = .001). The median Kujala score increased from 52 to 77 (P = .001), and the median Tegner activity level improved from 3 to 4 (P = .001). No cases of osteotomy nonunion were reported. One case (3.2%) of patellar instability recurrence and 3 cases (6.5%) with painful hardware were observed. TTO-d resulted in good radiographic, clinical, and functional outcomes providing proper patellar stability to patients with patella alta. TTO-d appears to be a safe and efficient procedure with low complication rates, providing an additional tool for the personalized treatment of patellar instability.

7 December 2022 in Arthroscopy
Verified
Journal Article
Closed access
CLChilan B. G. Leite
Chilan B. G. Leite
GMGergo Merkely
Gergo Merkely
MZMolly Zgoda
Molly Zgoda
EFEvan M. Farina
Evan M. Farina
SGSimon Görtz
Simon Görtz
CLChristian Lattermann
Christian Lattermann

16 July 2023 in The American Journal of Sports Medicine
Verified
Journal Article
Closed access
CLChilan B. G. Leite
Chilan B. G. Leite
GMGergo Merkely
Gergo Merkely
EFEvan M. Farina
Evan M. Farina
RSRichard Smith
Richard Smith
SGSimon Görtz
Simon Görtz
CLChristian Lattermann
Christian Lattermann
Background: Coronal and sagittal malalignment of the knee are well-recognized risk factors for failure after anterior cruciate ligament (ACL) reconstruction (ACLR). However, the effect of axial malalignment on graft survival after ACLR is yet to be determined. Purpose: To evaluate whether increased tibiofemoral rotational malalignment, namely, tibiofemoral rotation angle (TFA) and tibial tubercle–trochlear groove (TT-TG) distance, is associated with graft failure after ACLR. Study Design: Cohort study; Level of evidence, 3. Methods: In this retrospective matched control study of a single center’s database, 151 patients who underwent revision ACLR because of graft failure (ACLR failure group, defined as symptomatic patients with anterior knee instability and an ACL graft tear appreciated on magnetic resonance imaging [MRI] and confirmed during arthroscopic surgery) were compared with a matched control group of 151 patients who underwent primary ACLR with no evidence of failure after ≥2-year follow-up (intact ACLR group). Patients were matched by sex, age, and meniscal injury during primary ACLR. Axial malalignment was assessed on preoperative MRI through the TFA and the TT-TG distance. Sagittal alignment was measured through the posterior tibial slope on MRI. The optimal TFA cutoff associated with graft failure was identified by a receiver operating characteristic curve. The Kaplan-Meier curve with log-rank analysis was performed to evaluate the influence of the TFA on ACLR longevity. Results: The mean age was 25.7 ± 10.4 years for the ACLR failure group and 25.9 ± 10.0 years for the intact ACLR group. Among all the included patients, 174 (57.6%) were male. In the ACLR failure group, the mean TFA was 5.8°± 4.5° (range, −5° to 16°), while it was 3.0°± 3.3° (range, −3° to 15°) in the intact ACLR group ( P < .001). Neither the TT-TG distance nor the posterior tibial slope presented statistical differences between the groups. The receiver operating characteristic curve suggested an optimal TFA cutoff of 4.5° for graft failure (area under the curve = 0.71; P < .001; sensitivity, 68.2%; specificity, 75.5%). Considering this a threshold, patients who had a TFA ≥4.5° had 6.6 times higher odds of graft failure compared with patients with a TFA <4.5° ( P < .001). Survival analysis demonstrated a 5-year survival rate of 81% in patients with a TFA <4.5°, while it was 44% in those with a TFA ≥4.5° ( P < .001). Conclusion: An increased TFA was associated with increased odds of ACLR failure when the TFA was ≥4.5°. Measuring the TFA in patients with ACL tears undergoing reconstruction may inform the surgeon about additional factors that may require consideration before ACLR for a successful outcome.

14 March 2023 in Journal of ISAKOS
Verified
Journal Article
Open access
CLChilan B. G. Leite
Chilan B. G. Leite
BHBetina Bremer Hinckel
Betina Bremer Hinckel
GRGabriel Fernandes Ribeiro
Gabriel Fernandes Ribeiro
PGPedro Nogueira Giglio
Pedro Nogueira Giglio
TSTarsis Padula Santos
Tarsis Padula Santos
RGRiccardo Gomes Gobbi
Riccardo Gomes Gobbi
To report outcomes and re-dislocation rates of medial patellar stabilizers reconstruction without bone procedures for correction of anatomical risk factors for patellar instability in skeletally immature patients; to compare isolated medial patellofemoral ligament (MPFL) reconstruction to combined MPFL and medial patellotibial ligament (MPTL) reconstruction in this population. Patients with open physis and bone abnormalities including patella alta and/or increased tibial tubercle-trochlear groove (TT-TG) distance and/or trochlear dysplasia underwent MPFL reconstruction, either isolated or associated with MPTL reconstruction. Preoperative, 1-year follow-up and the latest follow-up (5 years minimum) data were collected. Radiological and clinical evaluations were conducted, with special attention to failure rate. Comparison of results from isolated MPFL and combined MPFL/MPTL reconstructions was performed. Twenty-nine patients were included, 19 in the isolated MPFL group (median 14 years old; follow-up 5.8 ​± ​1.7 years) and 10 in the combined MPFL/MPTL group (median 13.5 years old; follow-up 5.2 ​± ​1.4 years). Kujala and Tegner scores increased over time, although without statistically significant differences between the two groups at the latest follow-up (p ​= ​0.840 and p ​> ​0.999, respectively). During follow-up, 5 of 19 (26.3%) isolated MPFL and 2 of 10 (20%) MPFL/MPTL reconstructions experienced recurrence of patellar dislocation (p ​> ​0.999). Trochlear dysplasia type D (p ​= ​0.028), knee rotation (p ​= ​0.009) and lateral patellar tilt angle (p ​= ​0.003) were associated with patellar instability recurrence. The isolated MPFL group showed increased laxity on physical exam at the latest follow-up compared to the 1-year follow-up (patellar glide test (p ​= ​0.002), patellar tilt test (p ​= ​0.042) and subluxation in extension (p ​= ​0.019). This increased laxity was not observed in the MPFL/MPTL group (p ​> ​0.999). Comparing both groups, the glide test was significantly better in the combined MPFL/MPTL group in comparison to the isolated MPFL reconstruction group at the latest follow-up (p ​= ​0.021). MPFL reconstruction in isolation or combined with MPTL reconstruction in skeletally immature patients with additional uncorrected anatomical patellofemoral abnormalities leads to acceptable clinical outcomes within a minimum of 5 years follow-up, although has a high failure rate of 24.1%. Addition of a MPTL reconstruction to the MPFL may result in decreased patellar laxity on physical exams, as demonstrated by better patellar glide test, patellar tilt test and subluxation in extension. Level III; retrospective cohort study.

24 August 2023 in Current Osteoporosis Reports
Verified
Journal Article
Closed access
PDF file
CLChilan B. G. Leite
Chilan B. G. Leite
GMGergo Merkely
Gergo Merkely
JCJulia F. Charles
Julia F. Charles
CLChristian Lattermann
Christian Lattermann

17 January 2023 in Journal of Cellular Physiology
Verified
Journal Article
Closed access
CLChilan B. G. Leite
Chilan B. G. Leite
LTLuciana P. Tavares
Luciana P. Tavares
MLMagno S. Leite
Magno S. Leite
MDMarco K. Demange
Marco K. Demange