In recent years, the e-commerce sector has undergone continuous adaptation to both consumer needs and the economic context. This adaptation is driven by technological advances and the development of new software products. The present study aimed at achieving two primary objectives. First, it sought to assess the current state of e-commerce development in Romania within the broader European context. Second, it identified the use of AI-driven automation as a potential strategy for improving e-commerce in the country. To this end, e-commerce indicators were extracted from the questionnaire “ICT Usage and E-commerce in Enterprises,” which was conducted by National Statistical Authorities and centralized at the level of the European Commission. The questionnaire was carried out on a sample of 157,000 companies. A range of sophisticated techniques were employed to these indicators with the aim of reducing their dimensionality and classification error, with the objective of achieving a robust classification with the lowest possible error rate. We then proceeded to analyze Romania’s position in this ranking and, given the structure of e-commerce companies in the country, proposed the use of AI-driven automation as a potential strategy for enhancing activity in this sector.