Elzem Şen

Dr. Elzem Şen


Research Focus & Metrics

Academic Career Length

7Years (2020-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

View All Publications
1 October 2022 in Turkish Journal of Anaesthesiology and Reanimation
Verified
Journal Article
Open access
HBHaydar Bektas
Haydar Bektas
SGSitki Goksu
Sitki Goksu
EŞElzem Şen
Elzem Şen
Intubation,laryngoscopy,Macintosh blade,videolaryngoscopy

1 January 2020 in Urology Research and Practice
Verified
Journal Article
Closed access
EŞElzem Şen
Elzem Şen
DKDavut Sinan Kaplan
Davut Sinan Kaplan
ZBZehra Bozdağ
Zehra Bozdağ
MOMustafa Orkmez
Mustafa Orkmez
AMAyşe Mızrak
Ayşe Mızrak
ÖBÖmer Bayrak
Ömer Bayrak
Objective: To evaluate the protective effect of tramadol on renal tissue in rats with induced renal ischemia-reperfusion injury (I/R injury), and its effects on oxidative stress. Material and methods: Thirty adult, male Wistar rats weighing 250–300 g were selected as subjects. Rats were randomized into 3 groups: group 1, sham; group 2, renal I/R injury; and group 3, renal I/R+Tramadol. In order to obtain ischemia in groups 2 and 3, renal artery was clamped for 1 h. Total oxidant status (TOS) and total antioxidant capacity (TAC) were analyzed using biochemical assays in the serum samples. Results: TOS values were measured as 1.68±0.4 in group 1, 3.35±1.0 in group 2, and 3.49±0.9 in group 3. When group 1 was compared with group 2 and group 3, the TOS values of group 1 were significantly lower (p0.05). TAC values were measured as 1.65±1.4 in group 1, 1.85±0.1 in group 2, and 2.79±0.6 in group 3. The antioxidant status of group 1 was not significantly different from that of group 2 (p>0.05), whereas there was a significant difference between group 1 and group 3 (p>0.05). Conclusions: Tramadol has positive effects on antioxidant levels in renal I/R injury. We think that tramadol may be used in patients who underwent renal surgery and have I/R injury risk. There is a need for studies on this subject including human series. Cite this article as: Şen E, Kaplan DS, Bozdağ Z, Örkmez M, Mızrak A, Şen H, et al. The effect of tramadol on oxidative stress total antioxidant levels in rats with renal ischemia-reperfusion injury. Turk J Urol 2020; 46(5): 388-92.

11 April 2025 in BMC Anesthesiology
Verified
Journal Article
Open access
PDF file
EŞElzem Şen
Elzem Şen
SGSuleyman Ganidaglı
Suleyman Ganidaglı
AMAyse Mizrak
Ayse Mizrak
BUBerna Kaya Ugur
Berna Kaya Ugur
MCMehmet Cesur
Mehmet Cesur
LPLutfiye Pirbudak
Lutfiye Pirbudak
The environmental impact and cost of volatile anesthetics are significant concerns in modern anesthesia. Automated end-tidal control systems aim to optimize anesthetic delivery by reducing waste and improving efficiency. This study compared the effectiveness of end-tidal controlled (EtControl) low-flow anesthesia to manually controlled (MC) low-flow anesthesia in elective surgeries. A randomized controlled trial. This study was conducted with 132 ASA Class I–II patients undergoing elective surgeries under general anesthesia. Patients were randomly assigned to the EtControl (n = 66) or MC (n = 66) groups. The primary outcomes included anesthetic agent consumption (mL). Anesthetic consumption was similar between the EtControl group (17.9 ± 2.63 mL) and the MC group (18.45 ± 2.44 mL) (p = 0.07). The rate of anesthetic consumption per minute was also comparable (0.120 mL/min vs. 0.127 mL/min; p = 0.514). EtControl and MC methods provide comparable safety and sevoflurane consumption during low-flow anesthesia. However, EtControl reduces manual adjustments, enhancing workflow efficiency and cost-effectiveness, with potential implications for reducing environmental impact.

14 May 2025 in Turkish Journal of Anaesthesiology and Reanimation
Verified
Journal Article
Open access
NGNeslihan Gezer
Neslihan Gezer
LPLütfiye Pirbudak
Lütfiye Pirbudak
EŞElzem Şen
Elzem Şen
AMAyşe Mızrak
Ayşe Mızrak
Evaluation of ASA, SORT, and ACCI Scores in Predicting the Need for Postoperative Intensive Care Unit Admissions After Hip Surgery - Turkish Journal of Anaesthesiology and Reanimation

1 August 2021 in Journal of Cardiothoracic and Vascular Anesthesia
Verified
Journal Article
Closed access
PDF file
EŞElzem Şen
Elzem Şen
SSSerap Ulusam Seckiner
Serap Ulusam Seckiner

1 June 2023 in Journal of Clinical and Analytical Medicine
Verified
Journal Article
Closed access
MYMustafa Emrah Yüksek
Mustafa Emrah Yüksek
LPLütfiye Pirbudak
Lütfiye Pirbudak
EŞElzem Şen
Elzem Şen
MAMehmet Mustafa Anlaş
Mehmet Mustafa Anlaş