Intra-abdominal hypertension, defined as an intra-abdominal pressure (IAP) equal to or above 12 mmHg is one of the major risk-factors for increased morbidity (organ failure) and mortality in critically ill patients. Therefore, IAP monitoring is highly recommended in intensive care unit (ICU) patients to predict development of abdominal compartment syndrome and to provide a better care for patients hospitalized in the ICU. The IAP measurement through the bladder is the actual reference standard advocated by the abdominal compartment society; however, this measurement technique is cumbersome, non-continuous, and carries a potential risk for urinary tract infections and urethral injury. Using microwave reflectometry has been proposed as one of the most promising IAP measurement alternatives. In this study, a novel radar-based method known as transient radar method (TRM) has been used to monitor the IAP in an in vitro model with an advanced abdominal wall phantom. In the second part of the study, further regression analyses have been done to calibrate the TRM system and measure the absolute value of IAP. A correlation of –0.97 with a p-value of 0.0001 was found between the IAP and the reflection response of the abdominal wall phantom. Additionally, a quadratic relation with a bias of −0.06 mmHg was found between IAP obtained from the TRM technique and the IAP values recorded by a pressure gauge. This study showed a promising future for further developing the TRM technique to use it in clinical monitoring.

A novel technique enabling ultrafast nondestructive characterization of multilayer dielectric structures is proposed. Actual estimations indicate that the data acquisition performance of electronic measurement systems of today allow deep submillimeter depth resolution, almost independently of the frequency. For a 10 GHz signal, e.g., this corresponds to significant subwavelength depth resolution. By means of a novel blind analysis method of the time-dependent reflected electromagnetic (EM) signal, detailed information on the geometrical and EM parameters such as the complex valued dielectric permittivity and magnetic susceptibility of each layer of the structure can be extracted. We validate the novel technique for different materials in the 10 GHz range and compare the results obtained with S-parameter measurements in the 9.5-10.5 GHz range using a vector network analyzer. We will discuss the impact of nonidealities on the accuracy of the retrieved parameters. The novel technique has the potential for deployment in a wide range of applications ranging from the piping industry, wind energy industry, automotive, biotechnology, food industry, pharmacy, and so on.

Introduction: Increased intra-abdominal pressure (IAP) has an important impact on morbidity and mortality in critically ill patients. The SERENNO Sentinel system (Serenno Medical, Yokne’am Illit, Israel) is a novel device that allows automatic and continuous IAP measurements. Aims: Pre-clinical validation in a bench model study comparing the new device with the gold standard method and two other continuous IAP measurement devices. Methods: IAP measurement with the novel SERENNO device (IAP_SER) was compared with the gold standard IAP_H2O (water column height) and two other automatic and continuous IAP measurement devices: IAP_CiM measured via the CiMON device (Pulsion Medical Systems, Munich, Germany) and IAP_SPIE measured using the Spiegelberg device (Spiegelberg, Hamburg, Germany), which previously received the CE mark for clinical applications. The IAP measurement was performed six times (n = 6) at each pressure value (between 0 and 35 mmHg) with different methods and the height of the water column in a bench-top phantom was used as the reference IAP for further interpretations. In addition to the quadruple comparisons, intra- and inter-observer variability of IAP measurements were also calculated. Correlation studies and Bland and Altman’s analyses were performed in addition to the concordance study. Results: The CiMON and Spiegelberg devices showed a greater dynamic range and standard deviation when recording IAP_CiM and IAP_SPIE compared with IAP_SER. In general, the maximum and minimum values of IAP recorded with each device (at each level of IAP_H2O) were significantly different from each other. However, the average values were in very good agreement. The highest correlation was observed between IAP_SER and IAP_H2O, and IAP_SER and IAP_SPIE (R = 0.99, p = 0.001 for both comparisons and intra- and inter-observer measurements). Although the CiMON and SERENNO systems were in very good agreement with each other, a slightly smaller correlation coefficient was found between them (R = 0.95, p = 0.001, and R = 0.96, p = 0.001 for intra- and inter-observer measurements, respectively). When compared to the gold standard (IAP_H2O), Bland and Altman’s analysis showed a mean difference of +0.44, −0.25, and −0.04 mmHg for the intra-observer measurements and +0.18, −0.75, and −0.58 mmHg for the inter-observer measurements for IAP_SER, IAP_CiM, and IAP_SPIE, respectively. IAP_SER showed a small positive bias (overestimation), while IAP_CiM and IAP_SPIE showed a negative bias (underestimation) when compared to IAP_H2O. Further statistical analysis showed a concordance coefficient of 100% with an excellent ability of the SERENNO system in tracking IAP_H2O changes. Conclusions: Pre-clinical validation of a new IAP monitoring device (SERENNO) showed very promising results when compared with the gold standard and other continuous techniques; however, clinical trials should be followed as the next stage of the validation process. Based on the actual research guidelines, the SERENNO system can be used interchangeably with the gold standard.

Organic coatings form an effective barrier between metals and their environment, providing them protection against corrosion. Corrosion on coated metals depends mainly on the diffusion of water through the coating, the loss of adhesion at the interface between the coating and the metal (delamination), the rate of the chemical and electrochemical reactions under the coating and the treatment of the metal surface before the coating application. Many aggressive ions are transported toward and inside the coating through water. In organic coatings, typically, the water absorbed by the coating affects the polymer matrix structure, and it causes swelling and stresses, which may result in cracks. Swelling and cracks enhance the transport of water into the solid polymer, and concurrently the diffusion of ions. Over time also, the chemical structure of the polymer may change, adversely affecting its barrier properties and overall performance. In this chapter, we focus on methods to quantify the transport of electrolyte in organic coatings. We mark out the main characteristics, advantages and limitations of each one of them.

Transient Radar Method (TRM) was recently proposed as a novel contact-free method for the characterization of multilayer dielectric structures including the geometric details. In this paper, we discuss and quantify the intrinsic and systematic errors of TRM. Also, solutions for mitigating these problems are elaborated extensively. The proposed solution for error correction will be applied to quantify experimentally the thickness of several single-layer dielectric structures with thicknesses varying from larger to smaller than the wavelength. We will show how the error correction method allows sub-wavelength thickness measurements around $\lambda /5$ .

Transient radar method (TRM) is introduced as a novel non-destructive testing (NDT) technique that is capable of analyzing fully blindly and simultaneously the electromagnetic (EM) properties as well as geometric parameters of deep sub-wavelength thin single layer slabs. This study focuses on the minimum detectable layer thickness by means of TRM, which mainly depends on the experimental setup configuration. In this article, the complex permittivity and thickness of three polyvinyl chloride (PVC) sheets are extracted by means of a differential TRM set-up. The thickness of these PVC sheets was 1 mm, 500 μm, and 300 μm that corresponded to λ /30, λ /60, and λ /100, respectively (λ is the wavelength in free space). The carrier frequency was 10 GHz and the experiments were done in a bistatic radar setup. A differential TRM structure was used in this experiment. Some error sources, such as switch leakage and non-perpendicular illumination as well as systematic errors are considered as well. The experimentally obtained results are as follows: the thickness of these samples were 1033 ± 12, 535 ± 11, and 302 ± 9 μm with 1.18%, 0.94%, and 2.89% relative error, respectively. Additionally, the complex permittivity of these samples was found as (2.73 ± 0.02)-(0.23 ± 0.01)j, (2.70 ± 0.02)-(0.20 ± 0.02)j, and (2.65 ± 0.02)-(0.37 ± 0.01)j, respectively. This novel technique has the potential for deployment in a wide range of applications ranging from the piping, wind energy industry, and automotive to biotechnology, food industry, clinical monitoring, and pharmacy.