Gozde Gursoy Cirkinoglu

Dr. Gozde Gursoy Cirkinoglu

orcid

Research Focus & Metrics

Academic Career Length

8Years (2019-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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30 January 2025 in Medical Science Monitor
Verified
Journal Article
Open access
Halide Hande ŞahinkayaHalide Hande Şahinkaya
Halide Hande Şahinkaya
ATALPER TABANLI
ALPER TABANLI
GOGulsen Ozgenc
Gulsen Ozgenc
CACaglar Ayar
Caglar Ayar
CACafer AK
Cafer AK
ZTzeki tuncel Tekgül
zeki tuncel Tekgül
BACKGROUND The main concern regarding lung-protective ventilation strategies during neurosurgery is the reduction in venous return and increase in cerebral blood flow when using high positive end-expiratory pressure (PEEP). This study aimed to evaluate and compare the changes in regional cerebral oxygen saturations (rSO2) during the use of 5 cmH₂O and 10 cmH₂O PEEP in patients undergoing craniotomy for tumor resection. MATERIAL AND METHODS The study was designed as a prospective, single-blind randomized controlled study. Patients aged between 18 and 70 years, scheduled for an elective craniotomy for tumor resection, were divided into 2 groups: 5 cmH₂O PEEP (Group Low PEEP) and 10 cmH₂O PEEP (Group High PEEP). The PEEP was applied during general anesthesia, for controlled mechanical ventilation. The main outcome was the measurement of rSO2 before dura opening. Changes in rSO₂, hemodynamic parameters, and peripheral oxygen saturation (SpO₂) during different periods of surgery were compared between the groups. RESULTS Sixty-four patients were included. There were no significant differences between the 2 groups regarding demographic data. Mean arterial blood pressure and changes in SpO₂ were statistically similar in all periods between the groups (P=0.141 and P=0.081). When compared with the baseline value, SpO₂ increased significantly at all measurement times (P<0.05). No difference was observed in rSO₂ values compared with baseline rSO₂ values between the groups (P=0.218). CONCLUSIONS PEEP at the level of 10 cmH₂O can be safely applied during craniotomy without altering hemodynamics, and without causing a decrease in rSO₂.

28 November 2022 in Turkish Journal of Intensive Care
Verified
Journal Article
Open access
VHVolkan Hanci
Volkan Hanci
GCGozde Gursoy Cirkinoglu
Gozde Gursoy Cirkinoglu
GUGözde Altuntaş Uzun
Gözde Altuntaş Uzun
YŞYasemin Şişecioğlu
Yasemin Şişecioğlu
SKSezen Korkut
Sezen Korkut
BYBüşra Manduz Yavuz
Büşra Manduz Yavuz
Amaç: Çalışmamızda yoğun bakım literatüründe nütrisyon konusunda en çok atıf alan 101 yayının bibliyometrik özelliklerinin değerlendirilmesi amaçlanmıştır. Gereç ve Yöntem: Çalışmamız için yerel etik onamı alınması sonrası “Institute for Scientific Information Web of Science (WOS)” sitesinde yer alan gelişmiş mod özelliği ve arama anahtarı “WC = Critical Care Medicine and TS = nutr* or WC = Critical Care Medicine and TI = nutr* or WC = Nutrition & Dietetics and TS = intensive care or WC = Nutrition & Dietetics and TI=intensive care or WC = Nutrition & Dietetics and TS = critical care or WC = Nutrition & Dietetics and TI = critical care” kullanılarak tarama yapıldı. Yoğun bakım literatüründe nütrisyon ile ilişkili en fazla atıf yapılan 101 çalışma belirlendi. İstatistik analiz amacıyla Statistical Package for the Social Sciences (SPSS) 24.0 programı kullanıldı. Gruplar ki-kare testi, Student’s t-testi, Kruskal-Wallis testi ve Mann- Whitney U testi ile analiz edildi. Bulgular: Nütrisyon konusunda 1975 yılı ile 2021 yılı arasında toplam 7,093 çalışma olduğu belirlendi. Atıf sayısı en yüksek olan makale Journal of Parenteral and Enteral Nutrition dergisinde yer alan, McClave Stephen A ve ark.’nın “Guidelines for the Provision and Assessment of Nutrition Support Therapy in the Adult Critically Ill Patient: Society of Critical Care Medicine and American Society for Parenteral and Enteral Nutrition (ASPEN)” başlıklı çalışmasıydı ve toplam 1,011 defa atıf yapılmıştı. Atıf sayısı en düşük olan çalışmalara ise 166 defa atıf yapılmıştı. En yüksek oranda atıf yapılan 101 çalışmanın %53,5’inin 2000-2009 yılları arasında yayınlanan çalışmalar olduğu belirlendi. Çalışmaların toplam atıf ortalaması 287,77±178,57 ve yıllık atıf ortalaması 21,86±35,46 olarak bulundu. Çalışmaların %20,8’i enteral nütrisyon, %20,8’i immün nütrisyon, %17,8’i ise nütrisyon sonuçları konularını içermekteydi. Çalışmaların yayınlandığı dergilerin %78,2’si Amerika Birleşik Devletleri, %7,9’u İngiltere, %7,9’u İskoçya kökenli dergilerdi. Çalışmaların en fazla yayınlandığı dergilerin ilk üç sırası Critical Care Medicine (%43,6), Intensive Care Medicine (%10,9), Clinical Nutrition (%7,9) ve Journal of Parenteral Enteral Nutrition (%7,9) olarak bulundu. Çalışmaların yayınlandıkları yıl, dergi ve derginin ülkesi, kıtası, çalışma türü, konu alanı ve grup otör olup olmaması ile yıllık olarak yapılan atıflar ortalaması arasında ve çalışma türü ile toplam atıf yapılma sayısı arasında istatistiksel açıdan anlamlı bir ilişki olduğu belirlendi (p

19 August 2019 in Turkish Journal of Intensive Care
Verified
Journal Article
Open access
KAKutlay Aydın
Kutlay Aydın
BEBegüm Ergan
Begüm Ergan
MTMurat Emre Tokur
Murat Emre Tokur
TÇTaner Çalışkan
Taner Çalışkan
GCGozde Gursoy Cirkinoglu
Gozde Gursoy Cirkinoglu
NGNecati Gökmen
Necati Gökmen
Amaç: Türkiye’de son yıllarda beyin ölümü teşhisi ve organ bağışını arttırmak amacıyla teşhis yöntemlerindeki değişiklikleri de kapsayan pek çok yeni uygulama yapılmasına rağmen bunların etkileri ile ilgili bilgilerimiz sınırlıdır. Bu çalışmanın amacı İzmir’de organ bağışının mevcut durumunu anlamak ve yeni düzenlemelerin beyin ölümü teşhisi ve organ bağışı üzerinde herhangi bir etkisi olup olmadığını öğrenmektir. Gereç ve Yöntem: Bir üçüncü basamak üniversite hastanesinde Ocak 2001 ve Aralık 2016 arasındaki beyin ölümü teşhisi konan tüm hastalar, hasta verileri, organ nakli durumu tıbbi kayıtlardan elde edildi. Bulgular: Çalışma süresince beyin ölümü teşhisi konan 303 hasta mevcuttu. Pediatrik grupta (n=42) en çok görülen teşhis travmatik beyin hasarıydı (%42,9). Bu hastalardan 12 hasta (%28,6) donör oldu. Yetişkin hasta grubunda (n=261) en sık görülen teşhis intrakraniyal kanamaydı (%39,8) ve 97 hasta (%37,2) donör olmuştu. beyin ölümü teşhis hızı yıllar içerisinde artmıştı (yasal düzenlemeden sonra %0,59’dan %0,67’ye yükselmişti), ancak organ nakil hızında artış yoktu (düzenlemeden önce %39,5, düzenlemeden sonra %26,5). Organ nakli yapılamamasının en sık görülen sebebi hem pediatrik, hem de yetişkin hasta grubunda hasta yakını reddiydi (pediatrik %83,3, yetişkin %86,6). Sonuç: Çalışma İzmir’de beyin ölümü teşhisinin yıllar içerisinde artmasına rağmen organ naklinin hala düşük kaldığını göstermektedir. Farkındalığı arttıracak ve organ nakline bakışı değiştirecek yeni stratejiler en kısa zamanda planlanmalıdır.

1 September 2023 in Journal of Surgery and Medicine
Verified
Journal Article
Open access
PDF file
ZTZeynep Tuncer
Zeynep Tuncer
NANurcan Akbulut
Nurcan Akbulut
UEUral Can Ekmekçi
Ural Can Ekmekçi
GCGozde Gursoy Cirkinoglu
Gozde Gursoy Cirkinoglu
VÖVesile Öztürk
Vesile Öztürk
YEYüksel Erkin
Yüksel Erkin
Background/Aim: Trigeminal neuralgia (TN) is a prevalent cranial nerve disorder. While inflammation has been implicated in neuropathic pain in numerous recent studies, its role in TN has remained uncertain. Given the increasing significance of neuroinflammation, this study aims to explore the association between inflammation and TN and to assess whether there are disparities in the monocyte to high-density lipoprotein ratio (MHR) and neutrophil to lymphocyte ratio (NLR) values between TN patients and healthy individuals. There is a dearth of literature concerning the link with MHR, a parameter extensively studied in cardiac research but unexplored in the context of TN. Methods: This retrospective cohort study encompassed 48 patients diagnosed with classical TN and 40 healthy controls treated at the neurology and pain clinic of Dokuz Eylül University. Demographic and clinical variables, such as age and gender, along with monocyte, neutrophil, lymphocyte, and high-density lipoprotein (HDL) levels, were retrospectively retrieved from medical records. Inflammation markers, namely MHR and NLR, were calculated. Nonparametric tests were employed to compare these markers between TN patients and healthy controls. Results: Regarding sociodemographic data, the average age of the patient group was 59.8, while that of the healthy group was 47.4. A significant age difference was observed between the patient and healthy groups (P<0.001). However, no significant differences between the groups regarding MHR or NLR values were detected. Conclusions: These findings may suggest the presence of an inflammatory process characterized by local neurogenic inflammation in the pathophysiology of TN. Further comprehensive studies are required to assess the utility of MHR as a readily applicable marker in neurological disorders with neuroinflammatory and neuropathic pain etiologies.

1 January 2026 in The Anatolian Journal of Cardiology
Verified
Journal Article
Open access
PDF file
GCGozde Gursoy Cirkinoglu
Gozde Gursoy Cirkinoglu
Halide Hande ŞahinkayaHalide Hande Şahinkaya
Halide Hande Şahinkaya
The Anatolian Journal of Cardiology - Peer-reviewed cardiology journal publishing original research, reviews, case reports. Impact Factor 1.5. The Anatolian Journal of Cardiology - Leading international cardiology journal with Impact Factor 1.5. Publishing original research, reviews, and case reports in cardiovascular medicine. Indexed in PubMed, Scopus, and Web of Science.

3 July 2023 in The European Research Journal
Verified
Journal Article
Open access
PDF file
ZTZeynep Tuncer
Zeynep Tuncer
FEFatma Aysen Eren
Fatma Aysen Eren
GCGozde Gursoy Cirkinoglu
Gozde Gursoy Cirkinoglu
SBSerbülent Gökhan Beyaz
Serbülent Gökhan Beyaz
Objectives: Parkinson's disease is a chronic, progressive neurodegenerative disorder. Pain is a common symptom in Parkinson's disease, but the prevalence, characteristics, and documentation of its relationship with Parkinson's disease are insufficient. In this study, it was aimed to evaluate the relationship between lumbar spine magnetic resonance imaging (MRI) findings in patients who received and did not receive Parkinson's treatment. Methods: The demographic characteristics of patients with diagnosed Parkinson's disease were retrospectively obtained from the records. Their pain was grouped and the Hoehn Yahr stage at the first examination, and the interventional treatments performed were recorded. MRI measurements were made in the axial plane and sagittal plane of the spinal canal, whereas Ligamentum flavum measurements were made on both the right and left sides. Results: Twenty-six patients were included in the study. The average age was 73.5. Notably, 57.7% of patients were not diagnosed with Parkinson's disease prior to admission, while the Hoehn Yahr stage mostly comprised Stage 2 with 53.8%. Additionally, low back, waist, and hip pain was observed in 84.6% (n = 22), whereas 61.5% (n = 16) of patients experienced radicular pain. Epidural injections accounted for 33.2%. On lumbar MRI, the most narrow spinal segment on axial measurement was shown to be L4-L5. The axial spinal canal measurement of the Hoehn Yahr 1 group was observed to be significantly lower than the Hoehn Yahr 2 group. Conclusions: Optimal management for lumbar pain that increases with age is currently inadequate. There is a need to conduct larger studies on pain complaints, which is one of the frequently experienced non-motor symptoms in Parkinson's disease, as well as the interventional methods applied.