Objective: This study aimed to determine the long-term patency duration and rate of thrombosis of autologous arteriovenous fistulas and synthetic grafts treated with endovascular methods in a large patient population. Methods: A total of 144 arteriovenous accesses (37 radiocephalic, 51 brachiobasilic, 41 brachiocephalic, and 15 femorofemoral) from 143 patients were included in the study. A total of 304 endovascular thrombolytic treatment procedures were performed for 94 (65%) arteriovenous fistula and 50 (35%) arteriovenous graft accesses. Results: The procedural technical success rate was 98.7%. The mean follow-up duration was 32.5 (range, 3–132) months. The primary patency rates for arteriovenous fistulas and arteriovenous grafts were 78% and 78% at 6 months, 66% and 63% at 1 year, and 45% and 0% at 36 months, respectively. The assisted primary patency rates for arteriovenous fistulas and arteriovenous grafts were 82% and 84% at 6 months, 71% and 69% at 1 year, 51% and 29% at 36 months, and 30% and 1% at 60 months, respectively. The secondary patency rates for arteriovenous fistulas and arteriovenous grafts were 94% and 93% at 6 months, 85% and 85% at 1 year, 58% and 59% at 36 months, and 47% and 48% at 60 months, respectively. Conclusion: Although the primary patency durations for arteriovenous fistulas were better after endovascular thrombolytic treatment than those for arteriovenous grafts, the long-term outcomes of assisted primary and secondary patency durations after repeated procedures were similar for both types of arteriovenous accesses.
30 September 2018 in Journal of Health Sciences and Medicine
Amaç: Çalışmamızda sinonazal bölge anatomik varyasyonlarından olan Haller hücresinin görülme sıklığını ve sinüzit ile ilişkisini bilgisayarlı tomografi (BT) ile değerlendirilmesini amaçladık.Gereç ve Yöntem: Bolu İzzet Baysal Devlet Hastanesi’nde 1 Ocak 2017-30 Mayıs 2018 tarihleri arasında multislice (Toshiba) 16 kesitli BT ile çekilen sinüs BT görüntüleri retrospektif olarak incelendi, Haller hücresinin görülme sıklığı belirlendi. Maksiller sinüsdeki mukozal değişikliklerin değerlendirilmesinde Mc Gay Lund sınıflandırması kullanıldı. Bulgular: Çalışmamıza dahil edilen 196 hastadan sadece bir hastada herhangi bir varyasyon izlenmemiştir. Haller hücresi görülme sıklığı %15,8 olarak tespit edildi. Tüm hastalarda maksiller sinüzit görülme sıklığı ise %63,7 idi. Hastalarda Haller hücre varyasyonu bulunması ile aynı tarafta maksiller sinüzit mevcut olması arasında istatistiksel olarak bağlantı tespit edilmedi. Haller hücre varyasyonu olan hastalarda aynı yönde maksiller sinüzit bulunma oranı %54,9 iken kontrol grubunda %63,3 olarak tespit edilmiştir. İki grup arasında da sinüzit varlığı açısından istatistiksel olarak anlamlı fark saptanmadı. Sonuç: Paranazal sinüslerin anatomisinin ayrıntılı bir şekilde ortaya konması hem tanı hem tedavi açısından önem arz etmektedir.
15 October 2022 in European Archives of Oto-Rhino-Laryngology
Objective: Transthoracic needle biopsy is a diagnostic method that has proven its reliability in lung nodules and is frequently applied in daily practice. The diagnostic accuracy of biopsies performed with computed tomography navigation is quite high, even if the lesion sizes are smaller than 1 cm. We aimed to evaluate the diagnostic accuracy and complications of the computed tomography-guided percutaneous transthoracic needle biopsy procedure performed in our center. Material and Methods: Patients who underwent computed tomography guided percutaneous transthoracic pulmonary nodule biopsy procedure between January 2017 and January 2020 were included in the study. The size and anatomic location of lesions, the distance between the pleura and the lesion, the angle of the needle with the pleura, the procedure time, the number of pathologic samples taken per patient, the total radiation dose, complications, and the pathological results of the lesions were analyzed from the patients’ computed tomography images and patients’ records. Results: Among the 161 patients admitted for the transthoracic percutaneous needle biopsy procedure, 135 were male (mean age 64.3±11.1 years) and 26 were females (mean age 61.3±15.4 years). The pathological evaluation of 32 patients were reported as non-diagnostic. The diagnostic accuracy of computed tomography guided transthoracic biopsy was calculated as 80.1%. Major complications occurred in 10 patients (6.2%), and minor complications occurred in 60 patients (37.2%). The rate of procedure requiring chest tube insertion was 4.9%. The mean effective radiation dose of the patients per procedure was calculated as 5.26±3.25 mSv. Conclusion: Computed tomography guided transthoracic biopsy procedure are a method with a high diagnostic accuracy rate, low rate of complications and can be preferred in all appropriate pulmonary nodules.
Background/Objectives: This study aimed to evaluate the ability of ChatGPT-5, a multimodal large language model, to perform automated ASPECTS assessment on non-contrast CT (NCCT) in patients with acute ischemic stroke. Methods: This retrospective, single-center study included 199 patients with anterior circulation AIS who underwent baseline NCCT before reperfusion therapy between November 2020 and February 2025. Each NCCT was evaluated by two human readers and by ChatGPT-5 using four representative images (two ganglionic and two supraganglionic). Interobserver agreement was measured with the intraclass correlation coefficient (ICC), and prognostic performance was analyzed using multivariable logistic regression and receiver operating characteristic (ROC) analysis for 3-month functional independence (mRS ≤ 2). Results: ChatGPT-5 demonstrated good-to-excellent agreement with expert consensus (ICC = 0.845; 95% CI, 0.792–0.884; κ = 0.79). ChatGPT-ASPECTS were independently associated with 3-month functional independence (OR = 1.28 per point; p = 0.004), comparable to consensus-ASPECTS (OR = 1.31; p = 0.003). Prognostic discrimination was similar between ChatGPT-5 and consensus scoring (AUC = 0.78 vs. 0.80; p = 0.41). Conclusions: ChatGPT-5 achieved high reliability and strong prognostic validity in automated ASPECTS assessment without task-specific training. These findings highlight the emerging potential of large language models for quantitative image interpretation, though clinical implementation will require multicenter validation and regulatory approval.
1 January 2023 in TURKISH JOURNAL OF MEDICAL SCIENCES
Background/aim: The aim of this study was to assess the effectiveness of a new quantitative index for the diagnosis of idiopathic normal pressure hydrocephalus. Materials and methods: This retrospective study was conducted at İstanbul University Cerrahpaşa Medical Faculty between January 2016 and November 2022. A total of 31 patients diagnosed with idiopathic normal pressure hydrocephalus were included in the study group and 48 patients were included in the control group. Measurement via the new Index was performed on a coronal section of magnetic resonance imaging at the level of the anterior commissure. Results: The new Index's mean diagnostic performance was 1.16 ± 0.08 in the study group, significantly lower (p < 0.0001) than the mean of 1.43 ± 0.10 in the control group. When a cutoff value of 1.23 was used for the new index, the sensitivity, specificity, positive predictive value, negative predictive value, and accuracy rates were 96.1%, 90.7%, 80.6%, 98%, and 91.3%, respectively. Conclusion: The new Index described here is an effective, feasible, reproducible, highly sensitive, and specific quantitative method that can contribute to the improved diagnosis of patients with idiopathic normal pressure hydrocephalus.