Thamer H Alsharif

Dr. Thamer H Alsharif

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Research Focus & Metrics

Academic Career Length

4Years (2023-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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11 June 2023 in Cureus
Verified
Journal Article
Open access
PDF file
TAThamer H Alsharif
Thamer H Alsharif
AGAmin G. Gronfula
Amin G. Gronfula
STShifaa Turkistani
Shifaa Turkistani
AAAbdulkarim M. Alshmlany
Abdulkarim M. Alshmlany
ZSZikra Sharourou
Zikra Sharourou
HSHesham Aboueleneein Sr.
Hesham Aboueleneein Sr.
Needle breakage during spinal anesthesia occurs infrequently and represents a serious complication with potentially adverse effects. The objective of this systemic review was to look at the incidence, risk factors, and preventative measures for broken spinal needles. A search of the literature on PubMed, Web of Science, and Embase databases and a manual web search was performed, with no filters and up to April 2023 from inception. Out of the 43 potential studies, 23 were included. The search terms for the full article reading were broken needle, spinal anesthesia, humans, and post-operative, and the exclusion criteria were systematic reviews, conference presentations, and non-full articles. A review of the 23 studies (24 cases) suggests an association between specific risk factors such as obesity and needle size and breaks. Identifying the risks and complications of needle breaks could help physicians modify their practice and inform their patients of any increased risks applicable to them.

10 May 2023 in Cureus
Verified
Journal Article
Open access
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TAThamer H Alsharif
Thamer H Alsharif
AAAbdulkarim T Alanazi
Abdulkarim T Alanazi
ADAhmed Deif
Ahmed Deif
HAHesham Aboueleneein
Hesham Aboueleneein
Spinal anesthesia is the most common mode of anesthesia utilized during caesarian sections worldwide. Despite its many advantages over general anesthesia in the pregnant cohort, uncommon and even catastrophic complications could occur due to patient-related, equipment-related, and procedure-related complications. One such uncommon event of a broken spinal needle during failed spinal anesthesia for a caesarian section and subsequent successful management is described here.

7 July 2023 in Cureus
Verified
Journal Article
Open access
PDF file
TAThamer H Alsharif
Thamer H Alsharif
AGAmin G. Gronfula
Amin G. Gronfula
LALamees H. Alghdali
Lamees H. Alghdali
MHMayasim Hejazi
Mayasim Hejazi
AAAbdulkarim Alanazi
Abdulkarim Alanazi
MAMohammed Alyousef
Mohammed Alyousef
The endoscopic approach has been recommended as a primary option for treating chordomas, and it is associated with better resection rates and fewer surgical complications than transcranial surgery. This review aimed to assess the long-term consequences and evidence in the current literature regarding the endoscopic approach's efficacy in treating skull-base chordoma in children. A systematic review was conducted based on the PubMed, Web of Science, and EMBASE databases to examine the clinical outcomes of endoscopic endonasal surgery for pediatric skull base chordoma tumors. The review included studies published in English that employed specific research designs and reported on pediatric patients with skull base chordoma. Of the 268 studies initially considered, 25 met our eligibility criteria and were included in the final analysis. The average age of the patients was 11.5 years, with approximately equal number of males and females. The endoscopic endonasal approach (EEA) was the most commonly used modality. Gross total resection (GTR) was achieved in 62.7% of patients, while 18.09% had a subtotal resection (STR), and 13.83% had near-total resection only. Most patients showed significant to moderate improvement from their baseline condition and had no recurrence during their follow-up. Our findings further endorse that the endoscopic approach is a viable primary treatment option for pediatric skull base chordoma.

21 May 2023 in Cureus
Verified
Journal Article
Open access
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TAThamer H Alsharif
Thamer H Alsharif
AAAbdulkarim T. Alanazi
Abdulkarim T. Alanazi
ADAhmed Deif
Ahmed Deif
AFAhmed A Fouda
Ahmed A Fouda
HAHesham Aboueleneein
Hesham Aboueleneein
HSHesham Aboueleneein Sr.
Hesham Aboueleneein Sr.
We present a case of a 47-year-old female with a swelling on her scalp that was at first thought to be trichilemmal cysts. After two years, she returned to her general practitioner with a larger scalp mass. Following a biopsy, histological analysis revealed dermatofibrosarcoma protuberans (DFSP). She then had the tumor completely removed, resulting in clean margins.

13 February 2026 in Surgical Neurology International
Verified
Journal Article
Open access
YBYousef Bassi
Yousef Bassi
TAThamer H Alsharif
Thamer H Alsharif
ZAZiad E Alzahrani
Ziad E Alzahrani
AAAbdulrahman Alofi
Abdulrahman Alofi
DKDanah Kamal Kabrah
Danah Kamal Kabrah
MAMashhour A. Alsuwat
Mashhour A. Alsuwat
Background: Brucellosis is an endemic zoonotic infection in Saudi Arabia, with thousands of cases reported annually. Although musculoskeletal involvement is common, spinal complications – particularly cervical spondylodiscitis with epidural abscess – are rare and often difficult to diagnose due to nonspecific symptoms. Delayed recognition may lead to neurological compromise requiring urgent intervention. Case Description: A 55-year-old farmer with regular exposure to cattle and a history of brucellosis presented with progressive right-sided weakness and neck pain. Magnetic resonance imaging revealed cervical stenosis with cord compression. Serology on admission showed Brucella immunoglobulin G positive, immunoglobulin M negative. The patient underwent anterior cervical decompression, biopsy, and fixation. Intraoperative cultures confirmed Brucella infection; however, species-level identification was not performed. Targeted antibiotic therapy with ceftriaxone 2g intravenous daily, doxycycline 100 mg orally twice daily, and rifampicin 600 mg orally daily was initiated. The patient showed gradual neurological recovery with complete resolution at follow-up. Conclusion: Spinal brucellosis, though rare, should be considered in endemic regions. Early diagnosis and combined surgical and medical management can prevent permanent neurological sequelae. The absence of Brucella species identification represents a limitation of this report.

31 July 2026 in Preprints.org
Verified
Preprint
Open access
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Badr HafizBadr Hafiz
Badr Hafiz
TAThamer H Alsharif
Thamer H Alsharif
Faisal Adnan SukkarFaisal Adnan Sukkar
Faisal Adnan Sukkar
FOFahad Okal
Fahad Okal
MEMaryam Zuhair Enani
Maryam Zuhair Enani
Saleh Salem BaeesaSaleh Salem Baeesa
Saleh Salem Baeesa
Background/Objectives: Expanded endoscopic endonasal approaches (EEA) provide direct ventral access to adult intradural skull base tumors; however, postoperative complications are variably defined and reported in the literature. This review aimed to synthesize the overall spectrum of adult intradural EEA complications and distinguish pathology-specific evidence from large mixed EEA complication cohorts. Methods: A PRISMA 2020 systematic review and meta-analysis searched PubMed/MEDLINE, Embase, and Web of Science from database inception through July 2026. Eligible studies included adults or adult-separable subgroups undergoing expanded EEA for intradural skull base tumors. The primary outcomes were CSF leak, meningitis or intracranial infection, new neurological deficit or vascular injury/stroke, hydrocephalus, mortality, and postoperative seizures. Pathology-specific adult intradural series with exact counts were quantitatively synthesized when appropriate, and large mixed EEA cohorts were summarized separately when the eligible subgroup was not separable. Results: The full-text screening set included 48 reports. Five exact-count reports, including one mixed-age contextual report, contributed to the CSF leak meta-analysis and yielded a random-effects incidence of 21.1% (95% CI, 12.2%-33.8%; I² = 69.4%). Excluding the mixed-age reports yielded 23.8% (95% CI, 14.5%-36.6%). Meningitis was reported in 6/166 patients (3.6%; 95% exact CI, 1.3%-7.7%), and new neurological deficit/vascular injury/stroke in 4/166 (2.4%; 95% exact CI, 0.7%-6.1%); these rare outcomes were summarized descriptively without continuity correction. Postoperative seizures were reported in 4/652 patients (0.6%) in two studies. Large mixed EEA cohorts have reported CSF leak rates of 1.6%-15.9% but these were not pooled because adult intradural tumor subsets were not separable. Conclusion: CSF leak was the most consistently reported complication after expanded EEA for adult intradural skull base tumors; however, its incidence varied substantially across pathologies and centers. Meningitis, neurological/vascular events, and seizures were uncommon in the extractable data and were better interpreted descriptively than as precise pooled rates. Large mixed EEA cohorts provide important safety context but cannot substitute standardized adult intradural, pathology-specific reporting.