Ben Zarzaur

Dr. Ben Zarzaur


Research Focus & Metrics

Academic Career Length

17Years (2010-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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24 June 2019 in Journal of Trauma and Acute Care Surgery
Verified
Journal Article
Closed access
PMPatrick B. Murphy
Patrick B. Murphy
SSSarah Severance
Sarah Severance
SSStephanie Savage
Stephanie Savage
SOSamilia Obeng-Gyasi
Samilia Obeng-Gyasi
LTLava Timsina
Lava Timsina
BZBen Zarzaur
Ben Zarzaur
BACKGROUND: Increasing health care costs and high deductible insurance plans have shifted more responsibility for medical costs to patients. After serious illnesses, financial responsibilities may result in lost wages, forced unemployment, and other financial burdens, collectively described as financial toxicity. Following cancer treatments, financial toxicity is associated with worse long-term health-related quality of life (HRQoL) outcomes. The purpose of this study was to determine the incidence of financial toxicity following injury, factors associated with financial toxicity, and the impact of financial toxicity on long-term HRQoL. METHODS: Adult patients with an Injury Severity Score of 10 or greater and without head or spinal cord injury were prospectively followed for 1 year. The Short-Form-36 was used to determine overall quality of life at 1 month, 2 months, 4 months, and 12 months. Screens for depression and posttraumatic stress syndrome were administered. The primary outcome was any financial toxicity. A multivariable generalized estimating equation was used to account for variability over time. RESULTS: Five hundred patients were enrolled, and 88% suffered financial toxicity during the year following injury (64% reduced income, 58% unemployment, 85% experienced stress due to financial burden). Financial toxicity remained stable over follow-up (80–85%). Factors independently associated with financial toxicity were lower age (odds ratio [OR], 0.96 [0.94–0.98]), lack of health insurance (OR, 0.28 [0.14–0.56]), and larger household size (OR, 1.37 [1.06–1.77]). After risk adjustment, patients with financial toxicity had worse HRQoL, and more depression and posttraumatic stress syndrome in a stepwise fashion based on severity of financial toxicity. CONCLUSION: Financial toxicity following injury is extremely common and is associated with worse psychological and physical outcomes. Age, lack of insurance, and large household size are associated with financial toxicity. Patients at risk for financial toxicity can be identified, and interventions to counteract the negative effects should be developed to improve long-term outcomes. LEVEL OF EVIDENCE: Prognostic/epidemiologic study, level III.

1 May 2011 in Journal of Trauma: Injury, Infection & Critical Care
Verified
Journal Article
Closed access
BZBen Zarzaur
Ben Zarzaur
RKRosemary A. Kozar
Rosemary A. Kozar
TFTimothy C. Fabian
Timothy C. Fabian
RCRaul Coimbra
Raul Coimbra
Conflicting data exist regarding pseudoaneurysm screening (PSA-S), initial angioembolization (IE), deep venous thrombosis prophylaxis (DVT-P), and activity limitation after hemodynamically stable blunt splenic injury (BSI). To determine whether there was consensus regarding BSI management, the multi-institutional trial committee of the American Association for the Surgery of Trauma (AAST) approved a survey of member practice patterns regarding BSI management. Over 2 months, AAST members were invited to participate in an online survey. Practice patterns and attitudes surrounding PSA-S, IE, DVT-P, and activity limitation after BSI were determined. The response rate was 37.5%. Practice patterns varied by injury grade. Observation only was thought appropriate for grades I (94.4%) and II (84.6%) injuries. For grades III to V injuries, fewer and fewer respondents felt observation only was appropriate. PSA-S was the most commonly used strategy for grades IV and V injuries (32.7% and 28.2%), and IE was thought to be appropriate by 23.5% of respondents for grade IV injuries and 25.5% of respondents with grade V injuries. Thirty percent of respondents felt that no DVT-P was indicated for adult patients with BSI. Recommendations regarding return to full activity varied by perceived risk to the patient and by injury grade. There is considerable variation in the opinions of AAST members regarding BSI management, particularly for high-grade injuries. These results will aid in the design of prospective observational and random trials to determine optimal BSI management.

1 March 2020 in Journal of Surgical Research
Verified
Journal Article
Closed access
PMPatrick B. Murphy
Patrick B. Murphy
SSStephanie A. Savage
Stephanie A. Savage
BZBen Zarzaur
Ben Zarzaur

1 July 2020 in JAMA Surgery
Verified
Journal Article
Open access
PDF file
BZBen Zarzaur
Ben Zarzaur
CSChristopher C. Stahl
Christopher C. Stahl
JGJacob A. Greenberg
Jacob A. Greenberg
SSStephanie A. Savage
Stephanie A. Savage
RMRebecca M. Minter
Rebecca M. Minter
The current health care environment is complex. Systems often cross US state boundaries to provide care to patients with a wide variety of medical needs. The coronavirus disease 2019 pandemic is challenging health care systems across the globe. Systems face varying levels of complexity as they adapt to the new reality. This pandemic continues to escalate in hot spots nationally and internationally, and the worst strain on health care systems may be yet to come. The purpose of this article is to provide a road map developed from lessons learned from the experience in the Department of Surgery at the University of Wisconsin School of Medicine and Public Health and University of Wisconsin Health, based on past experience with incident command structures in military combat operations and Federal Emergency Management Agency responses. We will discuss administrative restructuring leveraging a team-of-teams approach, provide a framework for deploying the workforce needed to deliver all necessary urgent health care and critical care to patients in the system, and consider implications for the future.

1 February 2011 in Journal of Trauma: Injury, Infection & Critical Care
Verified
Journal Article
Closed access
BZBen Zarzaur
Ben Zarzaur
JDJennifer M. DiCocco
Jennifer M. DiCocco
CSCharles P. Bs Shahan
Charles P. Bs Shahan
KEKatrina Emmett
Katrina Emmett
LMLouis J. Magnotti
Louis J. Magnotti
TFTimothy C. Fabian
Timothy C. Fabian
Background: Management of intra-abdominal hypertension with an open abdomen and planned ventral hernia results in decreased mortality. But, delayed abdominal wall reconstruction (DAWR) is necessary. Results after DAWR demonstrate acceptable recurrence, morbidity, and mortality rates. However, little is known about quality of life (QOL) after DAWR. The purpose of this study was to analyze QOL after DAWR. Methods: Patients who had DAWR >15 years were identified from operative logs of a trauma center. Patients were contacted, and a QOL assessment was administered in person or via telephone. The QOL assessment contained the Short-Form 36-Item Health Survey 1.0, the Posttraumatic Stress Disorder (PTSD) Checklist-Civilian Version, and the Centers for Epidemiologic Studies Depression Scale. Results: The QOL assessment was completed by 41 of 152 patients. The indication for open abdomen was injury in 37 (90%) and emergency operation in 4 (10%). Time to follow-up ranged from 9 months to 14.6 years after DAWR. Of 31 patients working before DAWR, 23% had not returned to work secondary to DAWR. Also, 65% screened positive for depression and 23% screened positive for PTSD. Compared with population norms Physical Component Scores were significantly lower for the study population (41.1 ± 13.2, p < 0.05). Conclusion: Patients who undergo DAWR have decreased physical functioning and have a high prevalence of PTSD and depression. Consideration should be given to screening for depression and PTSD in this patient population.

26 April 2021 in Trauma Surgery & Acute Care Open
Verified
Journal Article
Open access
PDF file
PMPatrick B Murphy
Patrick B Murphy
SSSarah Severance
Sarah Severance
EHEmma Holler
Emma Holler
LMLaura Menard
Laura Menard
SSStephanie Savage
Stephanie Savage
BZBen Zarzaur
Ben Zarzaur
Background The management of asymptomatic blunt cerebrovascular injury (BCVI) with respect to stroke prevention and vessel healing is challenging. Objectives The aim of this systematic review was to determine if a specific treatment results in lower stroke rates and/or improved vessel healing in asymptomatic BCVI. Data sources An electronic literature search of MEDLINE, EMBASE, Cochrane Library, CINAHL, SCOPUS, Web of Science, and ClinicalTrials.gov performed from inception to March 2020. Study eligibility criteria Studies were included if they reported on a comparison of any treatment for BCVI and stroke and/or vessel healing rates. Participants and interventions Adult patients diagnosed with asymptomatic BCVI(s) who were treated with any preventive medication or procedure. Study appraisal and synthesis methods All studies were systematically reviewed and bias was evaluated by the Newcastle-Ottawa Scale. No meta-analysis was performed secondary to significant heterogeneity across studies in patient population, screening protocols, and treatment selection. The main outcomes were stroke and healing rate. Results Of 8781 studies reviewed, 19 reported on treatment effects for asymptomatic BCVI and were included for review. Any choice of medical management was better than no treatment, but no specific differences between choice of medical management and stroke outcomes were found. Vessel healing was rare and the majority of healed vessels were following low-grade injuries. Limitations Majority of the included studies were retrospective and at high risk of bias. Conclusions or implications of key findings Asymptomatic BCVI should be treated medically using a consistent, local protocol. High-quality studies on the effect of individual antithrombotic agents on stroke rates and vessel healing for asymptomatic BCVI are required.