Journal of Medical Internet Research - International Scientific Journal for Medical Research, Information and Communication on the Internet #Preprint #PeerReviewMe: Warning: This is a unreviewed preprint. Readers are warned that the document has not been peer-reviewed by expert/patient reviewers or an academic editor, may contain misleading claims, and is likely to undergo changes before final publication, if accepted, or may have been rejected/withdrawn. Readers with interest and expertise are encouraged to sign up as peer-reviewer, if the paper is within an open peer-review period. Please cite this preprint only for review purposes or for grant applications and CVs (if you are the author). Background: The challenges faced by the Global South during the coronavirus disease 2019 (COVID-19) pandemic are compounded by the presence of informal settlements, which are typically densely populated and lacking in formalized sanitation infrastructure. Social distancing measures in informal settlements may be difficult to implement due to the density and layout of settlements. This study measures the distance between dwellings in informal settlements in Cape Town to identify the risk of COVID-19 transmission. Objective: The aim of this paper is to determine if social distancing measures are achievable in informal settlements in Cape Town, using two settlements as an example. We will first examine the distance between dwellings and their first, second, and third nearest neighbors and then identify clusters of dwellings in which residents would be unable to effectively practice social isolation due to the close proximity of their homes. Methods: Dwellings in the settlements of Masiphumelele and Klipfontein Glebe were extracted from a geographic information system data set of outlines of all informal dwellings in Cape Town. The distance to each dwelling’s first, second, and third nearest neighbors was calculated for each settlement. A social distance measure of 2 m was used (buffer of 1 m, as dwellings less than 2 m apart are joined) to identify clusters of dwellings that are unable to effectively practice social distancing in each settlement. Results: The distance to each dwelling’s first 3 nearest neighbors illustrates that the settlement of Masiphumelele is constructed in a denser fashion as compared to the Klipfontein Glebe settlement. This implies that implementing social distancing will likely be more challenging in Masiphumelele than in Klipfontein Glebe. However, using a 2-m social distancing measure, it was demonstrated that large portions of Klipfontein Glebe would also be unable to effectively implement social distancing. Conclusions: Effectively implementing social distancing may be a challenge in informal settlements due to their density. This paper uses dwelling outlines for informal settlements in the city of Cape Town to demonstrate that with a 2 m measure, effective social distancing will be challenging.

Future land cover changes may result in adjustments to biophysical drivers impacting on net ecosystem carbon exchange (NEE), catchment water use through evapotranspiration (ET), and the surface energy balance through a change in albedo. The Land Change Modeller (Idrisi Terrset 18.08) and land cover for 2000 and 2014 are used to create a future scenario of land cover for two catchment with different land management systems in the Eastern Cape Province for the year 2030. In the S50E catchment, a dualistic farming system, the trend shows that grasslands represented 57% of the total catchment area in 2014 decreasing to 52% by 2030 with losses likely to favour a gain in woody plants and cultivated land. In T35B, a commercial system, persistence of grasslands is modelled with approximately 80% coverage in both years, representing a more stable system. Finally, for S50E, NEE and ET will increase under this land cover change scenario leading to increased carbon sequestration but less water availability and corresponding surface temperature increases. This implies that rehabilitation and land management initiatives should be targeted in catchments under a dualistic farming system, rather than those which are predominantly commercial systems.

Aims/hypothesis: Our aim was to investigate the geospatial distribution of diabetic foot ulceration (DFU), lower extremity amputation (LEA) and mortality rates in people with diabetes in small geographical areas with varying levels of multiple deprivation. Methods: We undertook a population cohort study to extract the health records of 112,231 people with diabetes from the Scottish Care Information – Diabetes Collaboration (SCI-Diabetes) database. We linked this to health records to identify death, LEA and DFU events. These events were geospatially mapped using multiple deprivation maps for the geographical area of National Health Service (NHS) Greater Glasgow and Clyde. Tests of spatial autocorrelation and association were conducted to evaluate geographical variation and patterning, and the association between prevalence-adjusted outcome rates and multiple deprivation by quintile. Results: Within our health board region, people with diabetes had crude prevalence-adjusted rates for DFU of 4.6% and for LEA of 1.3%, and an incidence rate of mortality preceded by either a DFU or LEA of 10.5 per 10,000 per year. Spatial autocorrelation identified statistically significant hot spot (high prevalence) and cold spot (low prevalence) clusters for all outcomes. Small-area maps effectively displayed near neighbour clustering across the health board geography. Disproportionately high numbers of hot spots within the most deprived quintile for DFU (p < 0.001), LEA (p < 0.001) and mortality (p < 0.001) rates were found. Conversely, a disproportionately higher number of cold spots was found within the least deprived quintile for LEA (p < 0.001). Conclusions/interpretation: In people with diabetes, DFU, LEA and mortality rates are associated with multiple deprivation and form geographical neighbourhood clusters.

The focus of this paper is on the pre-packaged version of SEBS in ILWIS and the sensitivity of SEBS to some parameters over which the user has some control when using this version of the model, in order to make informed choices to limit uncertainties. The sensitivities of SEBS to input parameters are related to daily ET rather than energy flux results since this is of interest to water managers and other users of the results of the SEBS model. This paper describes some of the uncertainties introduced by the sensitivity of the SEBS model to (a) land surface temperature and air temperature gradient, (b) the choice of fractional vegetation formula, (c) displacement height and the height at which wind speed is measured, and (d) study area heterogeneity. It was shown that SEBS is sensitive to land surface temperature and air temperature gradient and the magnitude of this sensitivity depended on the land cover and whether or not the wet-limit had been reached. The choice of fractional vegetation cover formula was shown to influence the daily ET results by up to 0.7 mm. It was shown that the height of the vegetation canopy should be considered in relation to the weather station reference height to avoid the sensible heat flux from becoming unsolvable due to a negative ln calculation. Finally the study area was shown to be heterogeneous although the resolution at which fluxes were calculated did not significantly impact on energy partitioning results. The differences in the upscaling from evaporative fraction to daily ET at varying resolutions observed implies that the heterogeneity may play the biggest role in the upscaling and the influence of albedo on this calculation should be studied.

Australian acacias have spread to many parts of the world. In South Africa, species such as A. mearnsii and dealbata are invasive. Consequently, more effort has focused on their clearing. In a cont...