Yoğun bakım ünitesinde yatış sürecinde hasta yakınlarının bilgi, güven, destek, yakınlık ve rahatlık alt başlıkları ile sunulan psikososyal gereksinimleri mevcuttur. Bu psikososyal gereksinimler kişisel farklılıklar göstermektedir. Bu çalışmada, bazal anksiyete düzeyi yüksek ve düşük olan hasta yakınlarının gereksinimlerinin incelenmesi amaçlandı. Çalışma 3.basamak yoğun bakımda 1 Kasım 2018 - 28 Şubat 2019 tarihleri arasında tanımlayıcı araştırma olarak dizayn edildi. Çalışmaya dahil olma gönüllülük esasına dayanmakta olduğundan araştırmaya katılmayı kabul etmeyen 18 yaşın altında olan, dil farklılığı nedeniyle iletişim güçlüğü olan, postoperatif takip amacı ile yatırılan ve 48 saatten daha kısa yatışı bulunan hasta yakınları çalışma dışı bırakıldı. Çalışmada, ‘Kritik Bakım Aile İhtiyaçları Envanteri (CCFNI) ve ‘Beck Anksiyete Ölçeği’ kullanıldı. Belirlenen tarih aralığında yoğun bakım ünitesine yatan 303 hastadan 91’inin yakını çalışmaya dahil edildi. Anksiyete düzeylerine göre hasta yakınları ‘anksiyete düzeyi yüksek’ ve anksiyete düzeyi düşük’ olarak 2 gruba ayrıldı. Güven, bilgi, yakınlık, destek ve rahatlık alt grupları ayrı ayrı değerlendirildiğinde anksiyetesi yüksek olan bireylerde tüm gereksinimlerin daha yüksek olduğu tespit edildi. Her iki grup için de gereksinim sıralaması benzer olup, sırasıyla; bilgi, destek, yakınlık, güven ve rahatlık gereksinimlerinin bulunduğu tespit edildi. Yoğun bakımda yatan hasta yakınlarının bazal anksiyete düzeylerinin yüksek olması, güven, bilgi, yakınlık, destek ve rahatlık gereksinimlerini arttırmaktadır. Hasta yakınlarının ihtiyaçlarının anksiyete düzeyleri ile birlikte değerlendirilmesi uygun gözükmektedir. Bu dönemde hasta yakınları ile yanlış anlaşılmaların önlenmesi için iletişime önem verilmelidir.

Background: Vaccines against coronavirus disease-19 (COVID-19) have been effective in preventing symptomatic diseases, hospitalizations, and intensive care unit (ICU) admissions. However, data regarding the effectiveness of COVID-19 vaccines in reducing mortality among critically ill patients with COVID-19 remains unclear.Aims: To determine the vaccination status and investigate the impact of the COVID-19 vaccine on the 28-day mortality in critically ill patients with COVID-19.Study Design: Multicenter prospective observational clinical study.Methods: This study was conducted in 60 hospitals with ICUs managing critically ill patients with COVID-19. Patients aged >= 18 years with confirmed COVID-19 who were admitted to the ICU were included. The present study had two phases. The first phase was designed as a one-day point prevalence study, and demographic and clinical findings were evaluated. In the second phase, the 28-day mortality was evaluated.Results: As of August 11, 2021, 921 patients were enrolled in the study. The mean age of the patients was 65.42 +/- 16.74 years, and 48.6% (n = 448) were female. Among the critically ill patients with COVID-19, 52.6% (n = 484) were unvaccinated, 7.7% (n = 71) were incompletely vaccinated, and 39.8% (n = 366) were fully vaccinated. A subgroup analysis of 817 patients who were unvaccinated (n = 484) or who had received two doses of the CoronaVac vaccine (n = 333) was performed. The 28-day mortality rate was 56.8% (n = 275) and 57.4% (n = 191) in the unvaccinated and two-dose CoronaVac groups, respectively. The 28-day mortality was associated with age, hypertension, the number of comorbidities, type of respiratory support, and APACHE II and sequential organ failure assessment scores (p < 0.05). The odds ratio for the 28-day mortality among those who had received two doses of CoronaVac was 0.591 (95% confidence interval: 0.413-0.848) (p = 0.004).Conclusion: Vaccination with at least two doses of CoronaVac within six months significantly decreased mortality in vaccinated patients than in unvaccinated patients.

Purpose: The aim of this study was to determine the effectiveness of two different lung ultrasonography (LUS) methods that can be used in the diagnosis of coronavirus disease 2019 (COVID-19) and to investigate their correlations with computed tomography (CT).Methods: In this prospective, randomized, and single-blind study, 60 patients with COVID-19 were included. The patients were randomized to either the 12-zone LUS group (n=30) or the 14-zone LUS group (n=30). The correlation between LUS and thoracic CT scores was evaluated. As a secondary outcome measure, the characteristic features of the findings of thoracic CT and LUS were examined.Results: The study was completed with a total of 59 patients. Moderate and high correlations were found between the total CT and LUS scores in the 12-zone and 14-zone study groups. There were no statistically significant differences in the lesion types detected in patients using LUS and CT (P>0.05). The left lung lower lobe CT scores were statistically significantly lower in the 14-zone study group than in the 12-zone group (P=0.019). The left lower lobe CT and LUS scores were highly correlated in the 14-zone group (P<0.001, r=0.902).Conclusion: The results of our study indicated that the two different LUS examination methods performed in different patients had similar findings in terms of the diagnosis and their correlations with CT results.

Objectives: An exaggerated inflammatory immune response is observed in cases of COVİD 19. This study aims to evaluate the effects of vitamin C, as a significant modulator of inflammation, on the inflammatory parameters and mortality in patients followed up in the intensive care unit (ICU) during the pandemic. Methods: This single-center retrospective study included 160 adult patients with confirmed positive nasopharyngeal smear COVID-19 PCR test results, who were followed up in the ICU between 01 March and 01 August 2020. Hospital files were scanned and patients given and not given vitamin C were assigned, to Group 1 and Group 2, respectively. The Acute Physiology and Chronic Health Evaluation (APACHE II) scores, the data entries on demographics, ventilation, laboratory tests, duration of ICU stay, discharge, and mortality were compared. Interventions with antiviral and antibacterial agents. steroids, cytokine apheresis, and renal replacement therapy were evaluated. Results: Vitamin C treatment was started in patients with raised neutrophil/lymphocyte ratio (NLR) at admission to ICU, who made up 20% of the total 160 ICU patients. Mortality incidence was higher among patients with raised NLR. Vitamin C at the doses used did not affect the inflammatory parameters, length of stay or mortality, and 37.5% of the patients recovered and were discharged from the ICU. Conclusions: We think that vitamin C treatment will have positive effects on the initiation of COVID-19 and that the time of intiation of the therapy and the optimal doses used should be determined with prospective studies.

Amaç: İlaç-ilaç etkileşimi (İİE), birden fazla ilacın birlikte kullanımıyla ortaya çıkan, advers ilaç reaksiyonlarından (AİR) olup, ilaçların tedavideki etkinliğinin azalması ve komplikasyonlarla ilişkilidir. Yoğun bakım ünitesi (YBÜ) hastalarında çoklu ilaç kullanımı potansiyel İİE açısından bu hastaları risk grubu haline getirmektedir. Çalışmamızda, ülkemizdeki farklı yoğun bakımlarında benzer hasta gruplarındaki potansiyel ilaç-ilaç etkileşimlerini (pİİE) belirlemek istedik. Gereç ve Yöntem: Bu çalışma Türkiye’deki YBÜ’de yatan kritik hastalarda çok merkezli nokta prevalans çalışması olarak tasarlanmıştır. Hasta orderları Lexi interact online interaction checker program (https: //www.uptodate.com/drug-interactions) ile pİİE açısından analiz edildi. Bulgular: İki yüz otuz altı hasta verisi içinden yaş

Aims: This study aimed to investigate alarm fatigue, which has a negative impact on nurses working in intensive care units. Methods: A questionnaire of 20 questions consisting of the alarm fatigue scale in nursing and sociodemographic questions prepared on Google Forms was sent to the nurses working in intensive care units as a social messaging platform and e-mail between 1 January-1 February 2022. Results: 219 nurses provided feedback. Nurses working in adult intensive care units participated with 70.6%. It was observed that alarm fatigue scores decreased as the duration of working in the intensive care unit and the working time in the nurse increased. Conclusion: As the age and professional experience of the nurses increase, the fatigue caused by the alarms decreases. Since this situation may pose a danger to the safety of patients who young nurses follow in the first years of the profession, it would be appropriate to develop nurses' methods of coping with alarms.