Transcriptional identity of human dendritic cell subsets is mainly dictated by ontogeny rather than by signals derived from the cells’ final tissue microenvironment.

SIALOLITHIASIS accounts for more than 50% of the diseases of the large salivary glands in the head and neck. With a prevalence in central Europe of about 1.2%, sialolithiasis is thus the most common cause of acute and chronic infections.¹ More than 80% of all sialoliths are localized within the duct system of the submandibular gland and only 20% within the parotid gland.^2-4 Approximately 90% of submandibular stones are situated in the distal portion of the Wharton duct or at the hilum.⁵