Polylactide scaffolds were prepared for the cancellous bone regeneration by the phase inversion method with freeze-extraction variant. A preliminary investigation and the optimization of the process were performed. For the obtained scaffolds, regression equations determining the effect: PLLA concentration by weight in 1,4-dioxane; volume ratio of the porophore/PLLA solution in 1,4-dioxane; and implant-forming solution pouring temperature, on the open porosity and mass absorbability were determined. The conditions in which the obtained implants were characterized by the maximal absorbability with the open porosity greater than 90 % were obtained.

In the second part of the literature review, the selected biodegradable polymers used in medicine, including drug delivery systems (DDS), were characterized in terms of their properties, methods of synthesis and requirements specific to the particular applications. Due to their effectiveness in DDS systems, a potential use of biodegradable polymers as polymer carriers of antitubercular substances was indicated.

The paper is an extensive review of the literature concerning the methods of treatment of tuberculosis, present problems and requirements for modern therapy of the disease. The systems for controlled release of active substance (drug delivery systems, DDS) based on various polymer matrices as drug carriers were discussed. The forms of DDS having a potential application in the fight against tuberculosis were briefly presented.