Bettina Csilla Budai

Ms. Bettina Csilla Budai


Research Focus & Metrics

Academic Career Length

6Years (2021-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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26 December 2025 in Cancers
Verified
Journal Article
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BBBettina Csilla Budai
Bettina Csilla Budai
PMPetrana Martinekova
Petrana Martinekova
GCGefu Cai
Gefu Cai
DDDalma Dobszai
Dalma Dobszai
LFLili Fekete
Lili Fekete
SBStefania Bunduc
Stefania Bunduc
Background/Objectives: Incidence of malnutrition varies greatly among gastrointestinal (GI) cancer patients and has a major impact on prognosis. We performed a meta-analysis to identify risk factors for malnutrition risk, malnutrition diagnosis, and cachexia in patients with GI cancer. Methods: A systematic search was performed on 31 October 2025 on the PubMed (Medline), Embase, and Cochrane Library databases. Eligible studies reported on risk factors for malnutrition risk, malnutrition diagnosis, malnutrition-related complication risk and cachexia in adult patients with GI cancer. Articles on neuroendocrine tumours, primary cancer outside the GI tract, and the paediatric population were excluded. The random-effects model yielded the pooled odds ratios (ORs) and 95% confidence intervals (CIs) for the investigated risk factors. Results: A total of 37,624 records were identified. Data from 262,525 patients from 578 articles were included in the analysis. Older age (≥65) was associated with higher odds for malnutrition risk across all GI cancers. In gastric cancer, males had a lower odds for malnutrition risk (OR 0.84; 95% CI 0.75–0.95); however, the sex difference across other cancer types was heterogeneous, and mostly not significant. Tumour location influenced the odds for malnutrition-related complication risk in pancreatic ductal adenocarcinoma (head vs. body/tail—OR 1.48; 95% CI 0.98–2.23) and colorectal cancer (colon vs. rectal—OR 1.39; 95% CI 1.07–1.81; right-sided vs. left-sided—OR 1.54; 95% CI 1.34–1.77). Increased C-reactive protein alone indicated higher odds for malnutrition risk at baseline. Conclusions: Inflammatory biomarkers and tumour characteristics may indicate malnutrition risk in GI cancer at baseline. There is a great need for standardised and harmonised approaches in nutritional status assessment in GI cancer.

Verified
Journal Article
Open access
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JHJakub Hoferica
Jakub Hoferica
BBBettina Csilla Budai
Bettina Csilla Budai
ESEszter Ágnes Szalai
Eszter Ágnes Szalai
ÁZÁdám Zolcsák
Ádám Zolcsák
MEMarie Anne Engh
Marie Anne Engh
PBPeter Banovcin
Peter Banovcin
Background: Alcohol-related liver disease (ALD) affects 4.8% of the global population. Among these patients, between 13.4% and 19.6% suffer from alcoholic hepatitis (AH), which, in its severe form, is associated with significant short- and long-term mortality. Current therapeutic options are limited, offering only modest short-term survival benefits. Recent studies suggest that microbiota-based therapies may offer a novel therapeutic opportunity for patients with ALD. Methods: Databases including Embase, Medline, and CENTRAL were searched until 4 February 2026. The pre-registered protocol on PROSPERO (CRD42023467455) was followed without deviation. Studies comparing adult patients with ALD, treated with fecal microbiota transplantation (FMT) or standard of care (SOC), were included. Outcomes investigated included overall survival, alcoholic recidivism, adverse events (AEs), and disease severity scores. Risk of bias (ROB) was assessed using the ROBINS-I and ROB 2 tools. Hazard ratios (HR) were calculated for FMT versus SOC groups. Results: Overall, 10 studies were eligible for inclusion, with 339 patients eligible for synthesis. In these patients, FMT was associated with significantly improved overall survival compared to the SOC, with an HR of 0.50 (95% confidence interval (CI): 0.35–0.72; p = 0.0002). When comparing FMT with pentoxifylline, the HR was 0.45 (95% CI: 0.21–0.96; p = 0.0345), and when FMT was compared with nutritional support alone, the HR was 0.36 (95% CI: 0.19–0.66; p = 0.0001). But FMT did not reach statistical significance when compared to glucocorticoids. ROB analysis showed a moderate to high risk of bias, and the overall certainty of evidence was low. Discussion: FMT is a promising therapeutic option for improving short- and medium-term survival in patients with severe alcoholic hepatitis (SAH), particularly in those who are ineligible or unresponsive to corticosteroid therapy. However, given the risk of bias and low certainty of evidence, clinical significance remains uncertain. Confirmation in well-designed studies is needed.

30 July 2021 in Developments in Health Sciences
Verified
Journal Article
Open access
PDF file
BBBettina Csilla Budai
Bettina Csilla Budai
ALA. Lichthammer
A. Lichthammer
Purpose: The aim of this study was to assess the consumption frequency of sugar sweetened beverages, physical activity, BMI values and their relationships among university students.Material/Methods: The data collection has been carried out with the help of questionnaires. The target population were students between the ages of 18 and 30, who study at the Faculty of Health Sciences (67 students) or at the Faculty of Humanities (64 students). The frequency of beverage consumption was assessed with a Food Frequency Questionnaire (FFQ) designed for sugar sweetened beverages and physical activity with the short form of the International Physical Activity Questionnaire.Results: The most frequently consumed sugar sweetened beverage was freshly squeezed or 100% fruit juice in both faculties. The difference between the average BMI of the two groups was statistically significant (P = 0.035). A non-significant relationship was found between BMI and sugar sweetened beverages consumption.Conclusions: The most consumed sugar sweetened beverage was freshly squeezed or 100% fruit juice, but it contains a lot of added sugar that contributes to developing overweight. Health education programmes are needed to teach the students of every faculty about healthy drink consumption.