Viticulture is of great economic importance in the southern part of Bosnia and Herzegovina, thanks to favorable climatic conditions and a long-standing tradition of growing vines. The assortment is dominated by international varieties, as well as some autochthonous and domesticated varieties. The subject of the research is the analysis of the quality of Cabernet Sauvignon, Merlot, Vranac, and Blatina varieties at two localities in Herzegovina during the period 2020–2021. The paper examined the most important economic and technological characteristics, grape quality, and berry phenolic profile. A particularly pronounced variation of the tested characteristics during the research period was observed in the Merlot and Blatina varieties, while the Cabernet Sauvignon and Vranac varieties showed a slightly higher stability of the tested characteristics. Poorer grape quality during the research period was registered with the Blatina variety, which can be considered a varietal characteristic to some extent. The analyzed grape varieties were rich in polyphenols, and the impact of grape variety on the berry phenolic profiles was confirmed. The most abundant polyphenols in the analyzed grape samples were quercetin 3-O-glucoside and catechin gallate, followed by kaempferol 3-O-glucoside. The highest values of polyphenols were found mainly in the samples originating from Trebinje. Indigenous Balkan grape varieties (Vranac and Blatina) stood out with particularly high contents of some phenolics. Research has shown that climatic conditions have a significant influence on the most important characteristics of grapes, which are conditioned by genotypic specificities. The conditions for growing vines in the conditions of Herzegovina enable high quality in the production of grapes, especially the Cabernet Sauvignon and Vranac varieties. The autochthonous variety Blatina shows significant variations in grape quality during the test period, which was confirmed by the results of a larger number of studies in the previous period.

In the study, the morphological and structural properties of bunches and berries, as well as the chemical characterisation of three interspecific grapevine cultivars—‘Bronner’, ‘Muscaris’, and ‘Morava’—were studied. Sugars and organic acids in the grapes were analysed using high-performance liquid chromatography (HPLC), while phenolic compounds were analysed by HPLC–mass spectrometry. ‘Morava’ and ‘Muscaris’ showed higher Hue angle values, indicating a greener skin coloration compared with ‘Bronner’, which exhibited a more yellow skin colour. ‘Muscaris’ and ‘Bronner’ had higher bunch weights than ‘Morava’, while the 100-berry weight did not differ significantly among the varieties. ‘Bronner’ must had the highest titratable acidity, and ‘Muscaris’ had the highest sugar content. Flavanols were the main phenolic compounds in the grapes, accounting for 76–88% of the total phenolic content. The highest concentrations of flavanols and caftaric acid were found in ‘Bronner’ and ‘Muscaris’ berries, while ‘Morava’ had the highest flavonol content. All studied varieties achieved good grape and must quality and are therefore recommended for wine production. ‘Bronner’ and ‘Muscaris’ stood out for their high bunch weight and high concentrations of flavanols and total phenolics, which contribute significantly to wine taste and overall quality. ‘Muscaris’ berries had a high sugar content, making this variety suitable for producing wines with higher alcohol content. In contrast, ‘Bronner’ is recommended for wines requiring higher acidity levels.

Vines in Bosnia and Herzegovina are traditionally grown in the Herzegovina region, where, in addition to many international varieties, indigenous and domesticated varieties are also successfully grown. The most important varieties are Žilavka and Blatina, while others are found in a much smaller area. One of these is the Radovača variety, which is preserved in only one micro-locality in Herzegovina region. The paper presents the results of a two-year analysis (2017 - 2018) of the qualitative characteristics of grapes and wines of the Radovača variety. The average cluster weight ranged from 195,50 to 308,97g, and the weight of 10 berries ranged from 23,67g to 29,79g. A favorable proportion of the weight of berries in the cluster weight (96,63 - 97,86 g/100 gcluster) compared to the proportion of petioles (2,14 - 3,37 g/100 g cluster) was observed. The year had a significant impact on the observed characteristics, considering that the analyzed parameters had a slightly higher value during 2017. Oscillations in the value of TSS consequently caused oscillations in the alcohol content of the wine (13,88 - 8,19 %v/v). The values ​​of TTA in grape juice and TA of wine in the years of research were quite uniform, which may also indicate the genetic specificity of this variety in this respect. The content of phenolic compounds in grapes was also significant, especially in seeds (428,74 - 977,27 mg/kg). Regardless of the fluctuations in the years of research, the Radovača variety has a certain oenological potential, which is especially important considering that it is an indigenous grape variety.