Background: Preeclampsia remains a major cause of maternal and perinatal morbidity and mortality, and machine learning (ML) and artificial intelligence (AI) models have increasingly been proposed for risk prediction, diagnosis, monitoring, and prognosis. However, the extent to which key methodological details are visible from abstracts and bibliographic metadata remains unclear. Methods: We conducted an abstract-level systematic mapping review of ML/AI studies for preeclampsia (PE), hypertensive disorders of pregnancy (HDP), and directly related complications. Records were identified from ACM Digital Library, Elsevier/ScienceDirect, IEEE Xplore, PubMed, Scopus, SpringerLink, and snowballing. After DOI-based deduplication, abstract-availability checks, technical metadata filtering, and a two-stage eligibility audit, 29 primary ML/AI studies were retained for the final synthesis. Two authors independently re-audited the 145 technically retained records for eligibility. Initial agreement was 131/145 records (90.3%); for the binary include/exclude decision, Cohen’s kappa was approximately 0.764, indicating substantial agreement. Extraction was limited to title, abstract, year, DOI, and bibliographic metadata using a predefined RQ-aligned schema. Therefore, all frequencies represent information explicitly extractable at the abstract level and should be interpreted as lower-bound reporting estimates rather than full-text prevalence estimates. Results: Among the 29 eligible studies, tree-based models were the most frequently identifiable family (17/29), followed by linear/generalized linear models (15/29), support vector machines (9/29), and neural networks (8/29). The most frequently identifiable input modalities were EHR/clinical variables (21/29), demographics (10/29), laboratory variables (7/29), vital signs/blood pressure (7/29), and ultrasound/Doppler information (6/29). AUC was mentioned in 20/29 abstracts, but a numeric AUC value was extractable into the structured field in 14/29. These values were summarized descriptively and were not pooled because outcomes, prediction horizons, populations, predictors, and validation strategies were heterogeneous. External validation was explicitly identifiable in 8/29 abstracts, explainability-related methods in 5/29, and repository or dataset-source information in 1/29. Conclusions: The abstract-level evidence shows an active but heterogeneous ML/AI literature for PE/HDP prediction and related outcomes. However, abstracts often provide insufficient detail for robust comparative assessment of model validity, calibration, clinical readiness, reproducibility, and implementation. Future work should prioritize full-text evidence synthesis, standardized reporting, external and temporal validation, calibration, equity assessment, clinically meaningful explainability, and reusable data/model resources.

Immersive Virtual Reality (VR) environments are increasingly adopted in clinical psychology and stress-management contexts; however, their therapeutic effectiveness depends on the system’s ability to understand and dynamically respond to users’ affective states. Emotional regulation plays a key role in psychological resilience, directly influencing stress coping mechanisms, cognitive performance, and overall mental well-being. Despite recent advances, automatic recognition of scenario-associated affective conditions in VR remains challenging because head-mounted displays occlude facial features. This study proposes a VR-based serious game for affective training and regulation, in which users interact with goal-oriented scenarios targeting fear, anger, and joy. We introduce a multimodal affective computing model to objectively assess users’ emotional responses by integrating electrocardiogram (ECG) signals and posture-based features extracted through computer vision. An early-fusion architecture combined with a Long Short-Term Memory (LSTM) network captures temporal dependencies in synchronized multimodal data. We established a controlled experimental framework using immersive VR scenarios, enabling the collection of synchronized physiological and behavioral data from a cohort of 20 healthy adult participants. The proposed model was evaluated under a strict Leave-One-Subject-Out (LOSO) cross-validation scheme across independent subjects, achieving a robust inter-subject accuracy of $78.94\%\pm 10.77\%$ and a global macro F1-score of 0.635, demonstrating strong generalization to entirely unseen users without data leakage. Furthermore, the system maintained an outstanding balance in detecting active emotional states (recall > 80.0% for fear, anger, and joy). Additionally, subjective evaluations using the PANAS and SGU questionnaires confirmed the coherence between detected and perceived emotional states, as well as the system’s high usability. The results suggest the potential viability of combining immersive environments and multimodal affective computing to explore the technical feasibility of adaptive frameworks that could eventually translate into healthcare contexts. This work may contribute to the development of intelligent digital health technologies by providing a foundation for responsive VR systems that can monitor emotional regulation and are fully aligned with sustainable well-being ecosystems (SDG 3: Good Health and Well-being and SDG 10: Reduced Inequalities).

Background: Preeclampsia (PE) is a leading cause of maternal and perinatal morbidity, affecting 2–8% of pregnancies worldwide. In Ecuadorian public hospitals, clinical data are often fragmented, limiting the construction of complete datasets for prediction modeling. This study aimed to develop a Machine Learning (ML) framework to predict PE using demographic data from the Isidro Ayora Gynecology and Obstetrics Hospital (HGOIA), Quito, Ecuador. Methods: We proposed a custom automated Machine Learning (C-AutoML) workflow to evaluate six models (Logistic Regression, LightGBM, XGBoost, CatBoost, Multi-Layer Perceptron, and Random Forest) and compared its performance against a weighted ensemble built with Amazon SageMaker Canvas, optimizing for the F1-score. Model interpretability was analyzed using Shapley Additive Explanations (SHAP). Due to the scarcity of clinical variables at HGOIA, a synthetic dataset based on FullPIERS predictors was also generated and modeled. Results: On the hospital dataset, the SageMaker ensemble achieved an F1-score of 0.805, accuracy of 0.934, and AUC of 0.956, while the C-AutoML best single model (LightGBM) yielded comparable results (F1-score: 0.802, accuracy: 0.938, AUC: 0.944). SHAP analysis identified patient age as the most influential feature. On the synthetic dataset, Logistic Regression achieved perfect classification (F1-score: 1.0). Conclusions: The proposed C-AutoML framework matched the performance of the SageMaker weighted ensemble while relying on a single, interpretable model. Despite the current dependence on demographic data, the methodology shows promise for supporting PE diagnosis in resource-limited settings; future integration of clinical variables is expected to further enhance predictive power for risk stratification.