This study evaluates the performance of natural plant-derived coagulants as sustainable alternatives to conventional chemical coagulants in water treatment. Surface water samples were collected from the Meda Ela stream in Karadiyana, Sri Lanka, which is an urban water body impacted by leachate from the Karadiyana dumpsite, industrial discharges, and urban runoff. Grab samples were analyzed for key water quality parameters, including pH, conductivity, turbidity, dissolved oxygen (DO), chemical oxygen demand (COD), biochemical oxygen demand (BOD₅), settleable solids, total solids (TS), total dissolved solids (TDS), total suspended solids (TSS), total nitrogen, and total phosphorus. Several parameters exceeded permissible standards established by the Central Environmental Authority (CEA) of Sri Lanka, including turbidity (35 NTU; limit: 20 NTU), COD (80 mg/L; limit: 15 mg/L), TDS (1000 mg/L; limit: 500 mg/L), and TSS (100 mg/L; limit: 40 mg/L), indicating significant pollution levels. Jar test experiments were conducted to compare the coagulation efficiency of cowpea seeds (75.8%), fenugreek seeds (69.2%), papaya seeds (72.5%), okra pods (84.6%), and Moringa oleifera (drumstick) leaves (87%) with conventional alum (94.2%) at an optimum dosage of 12 mL/L. Among the tested plant-derived coagulants, Moringa oleifera leaves demonstrated the highest turbidity removal efficiency, reducing residual turbidity to 4.54 NTU. A low-cost integrated treatment system incorporating coagulation, flocculation, sedimentation, and filtration using sawdust and cotton wool was developed, achieving average removal efficiencies of 90.13% for turbidity, 88.57% for COD, 83.46% for TDS, and 74.83% for TSS, with all effluent parameters maintained within CEA permissible limits. The results confirm that locally available plant-derived coagulants, particularly Moringa oleifera leaves, offer an effective, environmentally friendly, and economically viable approach for sustainable water treatment, highlighting the potential of nature-based solutions in strengthening climate-resilient water management strategies.