In this work, a self-powered vibration sensing system is proposed, based on a spatial magnetic field energy harvester, a duty-cycled circuit module, a piezoresistive graphene-based vibration sensor, and a wireless communication unit. The energy harvester is capable of generating an output power of 729 μW under a magnetic field excitation of 0.11 mT at 50 Hz. The duty-cycled circuit module enables closed-loop self-powered operation of the sensing system by efficient power storage and periodic measurement, and LoRa wireless transmission. The graphene-based sensor exhibits stable low-frequency vibration responses and good linearity and can capture composite vibration signals containing 4 Hz and 50 Hz components. These results indicate the potential of the proposed system for future transmission-line vibration sensing applications.