George Ion

Prof. Dr. George Ion


Research Focus & Metrics

Academic Career Length

1Year (2026-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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6 August 2026 in Dentistry Journal
Verified
Journal Article
Open access
PDF file
GIGeorge Ion
George Ion
SMStefan Milicescu
Stefan Milicescu
ŞAŞtefan-Dimitrie Albu
Ştefan-Dimitrie Albu
Dan SlăvescuDan Slăvescu
Dan Slăvescu
CACristina-Crenguta Albu
Cristina-Crenguta Albu
Claudia Florina Bogdan-AndreescuClaudia Florina Bogdan-Andreescu
Claudia Florina Bogdan-Andreescu
Background/Objectives: Provisional restorations are essential for maintaining oral function, esthetics, periodontal health, and patient comfort during prosthodontic treatment. This study evaluated current clinical practices, material preferences, fabrication techniques, and digital technology adoption among Romanian dental practitioners. Methods: A cross-sectional survey was conducted between January and March 2025. The questionnaire was sent directly to a predefined closed list of 150 licensed dental practitioners, of whom 95 submitted complete responses (response rate: 63.3%). The questionnaire assessed professional characteristics, materials and fabrication techniques used for provisional restorations, attitudes toward digital technologies, educational sources, and clinical complications. Data were analyzed using descriptive statistics, association tests, and exploratory multivariable logistic regression. Results: Composite resin (77.9%) and acrylic resin (65.3%) were the most frequently reported materials. Direct fabrication was used by 51.6% of respondents, while 42.1% used indirect techniques. An affirmative response to the general item concerning current digital technology use was provided by 47.4% of participants. Faster and more efficient fabrication and superior intraoral adaptation were the principal perceived advantages of 3D-printed restorations, whereas high equipment and material costs represented the main perceived disadvantage. The exploratory multivariable analysis identified no statistically significant independent associations with digital technology utilization. Debonding (44.2%) and fracture (42.1%) were the most frequently reported complications. Conclusions: Among the surveyed practitioners, conventional materials and fabrication techniques remained widely used, while digital workflows showed incomplete integration. Larger, representative studies using clearly defined technology-specific outcomes are needed to evaluate the determinants and clinical implications of digital adoption in provisional prosthodontics.

26 August 2026 in Polymers
Verified
Journal Article
Open access
PDF file
Claudia Florina Bogdan-AndreescuClaudia Florina Bogdan-Andreescu
Claudia Florina Bogdan-Andreescu
ABAndreea Mariana Banateanu
Andreea Mariana Banateanu
CCCristina Chelu
Cristina Chelu
GIGeorge Ion
George Ion
VPVivyiana Paraschiv
Vivyiana Paraschiv
EREugenia Diana Rădulescu
Eugenia Diana Rădulescu
Poly(methyl methacrylate) (PMMA) is one of the most widely used polymeric biomaterials in prosthodontics and digital dentistry because of their clinical reliability and compatibility with computer-aided design/computer-aided manufacturing (CAD/CAM). Its widespread use raises questions regarding material consumption, manufacturing waste, recyclability, and circularity. A critical narrative review supported by a structured literature search was conducted. PubMed, Scilit, OpenAlex, and ScienceDirect were searched for English-language literature published from January 2000 to June 2026. Targeted Google Scholar searches, cross-referencing, standards, and official technical sources supplemented the search. Evidence was organized according to its directness to dental PMMA and synthesized thematically. Prepolymerized CAD/CAM PMMA provides consistent material quality and generally improved mechanical performance compared with conventionally processed PMMA; however, subtractive manufacturing generates disc remnants, milling particles, and polishing residues. Mechanical recycling and depolymerization demonstrate technical recovery potential, although evidence specific to heterogeneous dental waste streams, environmental performance, and clinical-grade reuse remains limited. Technical recyclability should not be automatically equated with a viable circular economy or a net environmental benefit. Future research should quantify dental PMMA waste, establish effective collection and recovery pathways, and integrate life-cycle assessments with clinical performance and safety standards.

5 September 2026 in Diagnostics
Verified
Journal Article
Open access
PDF file
ASArsenie Dan Spînu
Arsenie Dan Spînu
Lucia BUBULACLucia BUBULAC
Lucia BUBULAC
RARadu Andrei Amza
Radu Andrei Amza
ACAdrian Constantin
Adrian Constantin
LPLuciana Alexandra Pavelescu
Luciana Alexandra Pavelescu
VTViorica Tudor
Viorica Tudor
Background and Clinical Significance: Penile carcinoma is a rare malignancy in developed countries, yet it remains associated with significant morbidity due to its aggressive local behavior and potential for lymphatic dissemination. Human Papillomavirus (HPV) infection plays a central role in its pathogenesis, while lymph node involvement represents the most important prognostic factor. Case Presentation: In this retrospective case series (n = 3), we evaluated three representative patients treated at a tertiary referral center in Romania between August 2020 and December 2024. Clinical, pathological, and therapeutic data were analyzed, with emphasis on tumor stage, nodal involvement, surgical management, and follow-up outcomes. Immunohistochemical analysis, including p16 expression, was performed to assess HPV-related tumor profiles. Conclusions: Three representative cases illustrating distinct clinical scenarios were included. Patients with localized disease and negative lymph nodes achieved favorable long-term outcomes, including 3-year disease-free survival (documented follow-up through December 2023; follow-up data beyond 2023 were unavailable, capping documented disease-free follow-up at 36 months). In contrast, advanced disease with nodal metastasis was associated with poor prognosis despite aggressive multimodal treatment. Immunohistochemical profiling revealed both HPV-associated and HPV-independent tumor patterns, which appeared to correlate with clinical outcomes. A case of locally advanced disease demonstrated that radical surgical intervention combined with adjuvant therapy may achieve prolonged recurrence-free survival. Penile carcinoma requires prompt diagnosis and individualized management.