Carukshi Arambepola

Prof. Dr. Carukshi Arambepola

orcid

Research Focus & Metrics

Academic Career Length

20Years (2007-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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19 April 2016 in Journal of Medical Internet Research
Verified
Journal Article
Open access
CACarukshi Arambepola
Carukshi Arambepola
IRIgnacio Ricci-Cabello
Ignacio Ricci-Cabello
PMPavithra Manikavasagam
Pavithra Manikavasagam
NRNia Roberts
Nia Roberts
DFDavid P French
David P French
AFAndrew Farmer
Andrew Farmer
Journal of Medical Internet Research - International Scientific Journal for Medical Research, Information and Communication on the Internet

1 January 2016 in Seizure: European Journal of Epilepsy
Verified
Journal Article
Closed access
RMRoshini Murugupillai
Roshini Murugupillai
JWJithangi Wanigasinghe
Jithangi Wanigasinghe
RMRavi Muniyandi
Ravi Muniyandi
CACarukshi Arambepola
Carukshi Arambepola

8 August 2016 in BMC Public Health
Verified
Journal Article
Open access
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ITIshanka A. Talagala
Ishanka A. Talagala
CACarukshi Arambepola
Carukshi Arambepola
Unhealthy snacking is commonly seen among adolescents. Therefore, use of food labels is promoted for making healthier choices on packaged snacks. This study was conducted to assess the use of food labels in making choices on packaged snack and its associated factors among adolescents. A cross–sectional study was conducted in 2012 among 542 Grade 12 students in Sri Lanka. Eight classes were selected as ‘clusters’ for the study (two classes each from two schools that were selected randomly from each list of ‘Girls only’ and ‘Boys only’ schools in Colombo district). A self-administered questionnaire assessed their socio-demography, snacking behaviour, attitudes and nutrition knowledge related to food labels. Adolescents’ use of labels was assessed by three practices (label reading frequency, attention paid to label contents and correct interpretation of six hypothetical labels of snacks). Based on total scores obtained for the three practices, ‘satisfactory’ (score ≥75th percentile mark) and ‘unsatisfactory’ (score <75th percentile mark) label users were identified. Using SPSS, associations were assessed at 0.05 significance level using Chi-square-test. Of the participants, 51 % were males; 61 % spent their pocket money at least once/week on packaged snacks; predominantly on biscuits (85 %) and cola-drinks (77 %) and 88 % selected snacks on their own. The majority (74.5 %) was frequent (‘always’ or ‘most often’) label readers with female predominance (p < 0.05). Over 74 % paid attention frequently to the brand name (75 %), price (85 %) and nutrition panel (81 %). Over 64 % were able to select the better food label when given a choice between two snacks, although some did it for reasons such as attractive label (63 %). The majority (84 %) had good knowledge (obtaining more than the 75th percentile mark) on interpreting labels. Although not statistically significant, ‘unsatisfactory’ label use was higher among males (73 %), purchasing power (70.4 %) and unhealthy snacking behaviour (73 %). In contrast, among the marketing strategies, identifying known brands (73.2 %) and imported products (75.8 %) as ‘good’ products were significantly associated with ‘unsatisfactory’ label use (p < 0.05). Despite having good knowledge and positive attitudes, food label use is unsatisfactory among adolescents. Skills in reading labels should be addressed in the ‘School canteen policy’ in Sri Lanka.

22 December 2018 in BMC Hematology
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Journal Article
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MRMiruna Sudharshani Kalaimani Rabindrakumar
Miruna Sudharshani Kalaimani Rabindrakumar
VWV. Pujitha Wickramasinghe
V. Pujitha Wickramasinghe
LGLallindra Gooneratne
Lallindra Gooneratne
CACarukshi Arambepola
Carukshi Arambepola
HSHemantha Senanayake
Hemantha Senanayake
TTTharanga Thoradeniya
Tharanga Thoradeniya
Early detection and treatment of iron deficiency during pregnancy is crucial for optimum pregnancy outcomes. Anaemia is a late indictor of iron deficiency measured as Hb < 11 g/dL, and is widely used as a proxy for iron deficiency. We aimed to evaluate the role of red cell indices as a screening tool for early detection of iron deficiency among pregnant women in an urban area of Sri Lanka. A cross-sectional study was conducted among 110 apparently healthy pregnant women ≤12 weeks of gestation attending antenatal clinics in Colombo, Sri Lanka. Women already on nutritional supplements were excluded. Full blood count, serum ferritin (SF) and high sensitive C-reactive protein (hs-CRP) assessments were performed. The women with evidence of inflammation as indicated by hs-CRP > 10 mg/L were excluded (N = 20) from data analysis. Anaemia (Hb < 11 g/dL) and iron deficiency (SF < 30 μg/L) were defined according to WHO guidelines. Receiver operating characteristics curves were used to derive red blood cell indices that showed the optimal cut-offs in detecting early iron deficiency. Of the 90 women, 63 (70.0%) were iron deficient (SF < 30 μg/L), out of whom 10 (15.9%) were identified as having iron deficiency anaemia (Hb < 11 g/dL). A high sensitivity (> 70%) in the prediction of iron deficiency was obtained for the optimal cut-off values of Hb < 12.2 g/dL, MCV < 83.2 fl, MCH < 26.9 pg and MCHC 33.2 g/dL while maintaining a specificity > 40%. Iron deficiency can be predicted in early stages using Hb and red cell indices, which is much less expensive. This could be a useful method in areas with limited resources and a high prevalence of iron deficiency.

10 March 2008 in Tropical Medicine & International Health
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Journal Article
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CACarukshi Arambepola
Carukshi Arambepola
SASteven Allender
Steven Allender
RERuvan Ekanayake
Ruvan Ekanayake
DFDulitha Fernando
Dulitha Fernando
Summary: Objectives  Living in an urban area influences obesity. However, little is known about whether this relationship is truly independent of, or merely mediated through, the demographic, socio‐economic and lifestyle characteristics of urban populations. We aimed to identify and quantify the magnitude of this relationship in a Sri Lankan population.Methods  Cross‐sectional study of adults aged 20–64 years representing the urban (n = 770) and rural (n = 630) populations, in the district of Colombo in 2004. Obesity was measured as a continuous variable using body mass index (BMI). Demographic, socio‐economic and lifestyle factors were assessed. Gender‐specific multivariable regression models were developed to quantify the independent effect of urban/ rural living and other variables on increased BMI.Results  The BMI (mean; 95% confidence interval) differed significantly between urban (men: 23.3; 22.8–23.8; women: 24.2; 23.7–24.7) and rural (men: 22.3; 21.9–22.7; women: 23.2; 22.7–23.7) sectors (P < 0.01). The observed association remained stable independently of all other variables in the regression models among both men (coefficient = 0.64) and women (coefficient = 0.95). These coefficients equated to 2.2 kg weight for the average man and 1.7 kg for the average woman. Other independent associations of BMI were with income (coefficient = 1.74), marital status (1.48), meal size (1.53) and religion (1.20) among men, and with age (0.87), marital status (2.25) and physical activity (0.96) among women.Conclusions  Urban living is associated with obesity independently of most other demographic, socio‐economic and lifestyle characteristics of the population. Targeting urban populations may be useful for consideration when developing strategies to reduce the prevalence of obesity.

31 July 2015 in BMC Infectious Diseases
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JLJanarthani Lohitharajah
Janarthani Lohitharajah
NMNeelika Malavige
Neelika Malavige
ACAnthony Jin Shun Chua
Anthony Jin Shun Chua
MNMah Lee Ng
Mah Lee Ng
CACarukshi Arambepola
Carukshi Arambepola
TCThashi Chang
Thashi Chang
West Nile virus (WNV) has emerged as one of the most common causes of epidemic meningoencephalitis worldwide. Most human infections are asymptomatic. However, neuroinvasive disease characterized by meningitis, encephalitis and/or acute flaccid paralysis is associated with significant morbidity and mortality. Although outbreaks have been reported in Asia, human WNV infection has not been previously reported in Sri Lanka. Sera and cerebrospinal fluid (CSF) from 108 consecutive patients with a clinical diagnosis of encephalitis admitted to two tertiary care hospitals in Colombo, Sri Lanka were screened for WNV IgM antibody using enzyme-linked immunosorbent assay. Positive results were confirmed using plaque reduction neutralization test (PRNT). Patient data were obtained from medical records and by interviewing patients and care-givers. Three of the 108 patients had WNV IgM antibody in serum and one had antibody in the CSF. The presence of WNV neutralizing antibodies was confirmed in two of the three patients using PRNT. Two patients had presented with the clinical syndrome of meningoencephalitis while one had presented with encephalitis. One patient had CSF lymphocytic pleocytosis, one had neutrophilic pleocytosis while CSF cell counts were normal in one. CSF protein showed marginal increase in two patients. This is the first report of human WNV infection identified in patients presenting with encephalitis or meningoencephalitis in Sri Lanka. There were no clinical, routine laboratory or radiological features that were distinguishable from other infectious causes of meningoencephalitis.