Novel metal(II) complexes derived from 2-hydroxy-N′-((Z)-3-(hydroxyimino)-4-oxopentan-2-ylidene)benzohydrazide ligand (H₂L) were synthesized and characterized by elemental and thermal analyses (DTA and TGA), IR, UV-VIS,¹H-NMR, ESR and mass spectroscopy, magnetic susceptibilities, and conductivities measurements. The complexes adopt distorted octahedral geometry. The ESR spectra of the solid copper(II) complexes are characteristic tod9configuration and have an axial symmetry type of ad(x2-y2)ground state. Thegvalues confirmed the tetragonal octahedral geometry with a considerably ionic or covalent environment. The cytotoxic activity of the ligand and its metal complexes showed potent cytotoxicity effect against growth of human liver cancer HepG2 cell lines compared to the clinically used Sorafenib (Nexavar).

Highly ordered pure MCM-41 and In-MCM-41 mesoporous adsorbents (with Si/In = 95 (IM0.05) and Si/In = 90 (IM0.1)) were synthesized using the hydrothermal-assisted method. The structural, morphological and texture characteristics were investigated by XRD, N₂adsorption–desorption, SEM-EDX, TEM, diffuse reflectance (DR) and FTIR. The broadening XRD diffraction peaks as well as the shifts to higher and lower 2-theta in IM0.05 and IM0.1, respectively, confirmed the incorporation of indium atoms in the MCM-41 structure. SEM-EXD and TEM images showed that pure MCM-41 and IM0.05 preserve a highly long-range well-ordered hexagonal pore structure, on the other hand, high loading of indium (IM0.1) resulted in partially irregular pore-ordering and morphological defects related to a partial dissolution of MCM-41 structure. The infrared spectra of In-incorporated samples showed a decrease in the transmittance intensity of MCM-41 characteristic peaks with little shifts relative to the pure MCM-41 sample. The potential of pure MCM-41 and In-MCM-41 samples for adsorption of dyes was preliminarily investigated. The removal efficiency of both methylene blue and basic yellow-28 (BY28) was enhanced by the incorporation of indium in the MCM-41. The adsorption equilibrium data of BY28 dye on pure, IM0.05 and IM0.1 samples fitted well with Langmuir adsorption model with adsorption capacity of 123.46, 156.99 and 158.48 mg g⁻¹respectively. The calculated free adsorption energy obtained from D–R isotherm was found to be 26.7 kJ mol⁻¹referring to that the adsorption of BY28 on IM0.05 adsorbent is chemical. The adsorption kinetic of BY28 on IM0.05 sample followed the pseudo-second-order model. The adsorption experiments revealed that the prepared samples can be used as effective adsorbents for the removal of dyes in aqueous solutions with good recovery and recyclability.Graphical Abstract