Objectives The purpose of this review is to summarise the evidence from a systematic review and meta-analysis of observational studies that objectively measure daily steps and health outcomes. Design This is an umbrella review. Data sources PubMed, Embase, Scopus, the Cochrane Library and Web of Science databases were searched through 31 January 2024. Eligibility We included systematic reviews of observational studies (with or without meta-analysis) that assessed the association of objectively measured daily steps with human health-related outcomes. Methodological quality was assessed using ‘A MeaSurement Tool to Assess systematic Reviews 2’. Results A total of 10 systematic reviews and 6 health outcomes were included after excluding irrelevant and duplicate studies. Higher daily steps were associated with more benefits than harms for a range of health-related outcomes, including all-cause mortality, cardiovascular event, skeletal muscle lesions, metabolic diseases and respiratory disease. A dose-response analysis showed that an increase of 500–1000 steps per day was associated with lower all-cause mortality and cardiovascular events. Beneficial associations were also found in patients with asthma and acutely hospitalised older adults. Conversely, one study within a systematic review suggested that higher daily steps (≥10 000) might be associated with an increased 52% risk of meniscal pathologies in individuals without knee osteoarthritis. However, one study within a systematic review suggested a potential increased risk of meniscal pathologies in individuals without knee osteoarthritis. Specifically, those exceeding 10 000 steps per day showed a 52% increase in risk. Conclusion The results of this study suggest that daily steps are associated with a lower risk of all-cause mortality and cardiovascular events. Future research could focus on identifying specific populations that may benefit most from increased daily steps and exploring potential mechanisms to enhance our understanding of how daily steps contribute to improved health outcomes. PROSPERO registration number CRD42022347055.

China is adopting and promoting the mini-midline catheter insertion technique, which requires professional training to ensure its application and patient safety. This study aims to explore the effectiveness of the Train-the-Trainer model in nurse training for Mini-Midline Catheter Insertion. A medical center selected venous therapy specialist nurses for mini-midline catheter procedure training, after which these nurses became trainers and guided other nurses. The research utilized a mixed-methods design, incorporating puncture condition surveys and open-ended questions. Over the following six months, outcomes such as catheter insertion success rates were monitored, and nurses’ interviews were analyzed using the Kawakita Jiro method. A total of 675 mini-midline catheters were inserted in the study, with a success rate of 97.54%. The success rate for first-attempt punctures was 86.51%, with 584 successful cases and no catheterization-related complications. After training, expert consultations for catheter issues decreased from 28.46 to 9.25%. Additionally, three key themes of the training were identified: (1) enhancing nurses’ professional sense of achievement and job satisfaction through skill mastery; (2) familiar groups and environments are more conducive to improving training effectiveness; and (3) the multifaceted role opens up a brand new path for the professional development of nurses. The mini-midline catheter insertion training program based on the “train-the-trainer” model effectively ensures the standardization of nurses’ techniques and the safety of punctures while also cultivating educators and thus deserves widespread promotion. Not applicable.