Juan Perez-Mercader

Prof. Dr. Juan Perez-Mercader

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Research Focus & Metrics

Academic Career Length

32Years (1995-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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29 April 2019 in Proceedings of the National Academy of Sciences
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LZLi Zeng
Li Zeng
SJStein B. Jacobsen
Stein B. Jacobsen
DSDimitar D. Sasselov
Dimitar D. Sasselov
MPMichail I. Petaev
Michail I. Petaev
AVAndrew Vanderburg
Andrew Vanderburg
RWRobin D. Wordsworth
Robin D. Wordsworth
Significance: The discovery of numerous exoplanet systems containing diverse populations of planets orbiting very close to their host stars challenges the planet formation theories based on the solar system. Here, we focus on the planets with radii of 2–4 R ⊕ , whose compositions are debated. They are thought to be either gas dwarfs consisting of rocky cores embedded in H 2 -rich gas envelopes or water worlds containing significant amounts of H 2 O-dominated fluid/ice in addition to rock and gas. We argue that these planets are water worlds.

2 September 2020 in Polymer Chemistry
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SPSamuel Pearce
Samuel Pearce
JPJuan Perez-Mercader
Juan Perez-Mercader
PISA reaction networks alone, integrated with other networks, or designing properties into the amphiphiles confer functionalities to the supramolecular assemblies.

14 September 2018 in Macromolecular Rapid Communications
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GCGong Cheng
Gong Cheng
JPJuan Perez-Mercader
Juan Perez-Mercader

27 January 2017 in Scientific Reports
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AAAnders N. Albertsen
Anders N. Albertsen
JSJan K. Szymański
Jan K. Szymański
JPJuan Perez-Mercader
Juan Perez-Mercader
Giant micrometer sized vesicles are of obvious interest to the natural sciences as well as engineering, having potential application in fields ranging from drug delivery to synthetic biology. Their formation often requires elaborate experimental techniques and attempts to obtain giant vesicles from chemical media in a one-pot fashion have so far led to much smaller nanoscale structures. Here we show that a tailored medium undergoing controlled radical polymerization is capable of forming giant polymer vesicles. Using a protocol which allows for an aqueous reaction under mild conditions, we observe the macroscale consequences of amphiphilic polymer synthesis and the resulting molecular self-assembly using fluorescence microscopy. The polymerization process is photoinitiated by blue light granting complete control of the reaction, including on the microscope stage. The self-assembly process leads to giant vesicles with radii larger than 10 microns, exhibiting several emergent properties, including periodic growth and collapse as well as phototaxis.

18 May 2012 in PLOS ONE
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JFJames L Friar
James L Friar
TGTerrance Goldman
Terrance Goldman
JPJuan Perez-Mercader
Juan Perez-Mercader
Data on the number of Open Reading Frames (ORFs) coded by genomes from the 3 domains of Life show the presence of some notable general features. These include essential differences between the Prokaryotes and Eukaryotes, with the number of ORFs growing linearly with total genome size for the former, but only logarithmically for the latter. Simply by assuming that the (protein) coding and non-coding fractions of the genome must have different dynamics and that the non-coding fraction must be particularly versatile and therefore be controlled by a variety of (unspecified) probability distribution functions (pdf’s), we are able to predict that the number of ORFs for Eukaryotes follows a Benford distribution and must therefore have a specific logarithmic form. Using the data for the 1000+ genomes available to us in early 2010, we find that the Benford distribution provides excellent fits to the data over several orders of magnitude. In its linear regime the Benford distribution produces excellent fits to the Prokaryote data, while the full non-linear form of the distribution similarly provides an excellent fit to the Eukaryote data. Furthermore, in their region of overlap the salient features are statistically congruent. This allows us to interpret the difference between Prokaryotes and Eukaryotes as the manifestation of the increased demand in the biological functions required for the larger Eukaryotes, to estimate some minimal genome sizes, and to predict a maximal Prokaryote genome size on the order of 8–12 megabasepairs.These results naturally allow a mathematical interpretation in terms of maximal entropy and, therefore, most efficient information transmission.

24 July 2017 in Angewandte Chemie International Edition
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Bishnu Prasad BastakotiBishnu Prasad Bastakoti
Bishnu Prasad Bastakoti
JPJuan Perez-Mercader
Juan Perez-Mercader