The challenge of providing quality healthcare to underserved populations in low- and middle-income countries (LMICs) has attracted increasing attention from information and communication technology (ICT) professionals interested in providing societal impact through their work. Sana is an organisation hosted at the Institute for Medical Engineering and Science at the Massachusetts Institute of Technology that was established out of this interest. Over the past several years, Sana has developed a model of organising mobile health bootcamp and hackathon events in LMICs with the goal of encouraging increased collaboration between ICT and medical professionals and leveraging the growing prevalence of cellphones to provide health solutions in resource limited settings. Most recently, these events have been based in Colombia, Uganda, Greece and Mexico. The lessons learned from these events can provide a framework for others working to create sustainable health solutions in the developing world.

Feature selection (FS) has attracted the attention of many researchers in the last few years due to the increasing sizes of datasets, which contain hundreds or thousands of columns (features). Typically, not all columns represent relevant values. Consequently, the noise or irrelevant columns could confuse the algorithms, leading to a weak performance of machine learning models. Different FS algorithms have been proposed to analyze highly dimensional datasets and determine their subsets of relevant features to overcome this problem. However, very often, FS algorithms are biased by the data. Thus, methods for ensemble feature selection (EFS) algorithms have become an alternative to integrate the advantages of single FS algorithms and compensate for their disadvantages. The objective of this research is to propose a conceptual and implementation framework to understand the main concepts and relationships in the process of aggregating FS algorithms and to demonstrate how to address FS on datasets with high dimensionality. The proposed conceptual framework is validated by deriving an implementation framework, which incorporates a set of Phyton packages with functionalities to support the assembly of feature selection algorithms. The performance of the implementation framework was demonstrated in several experiments discovering relevant features in the Sonar, SPECTF, and WDBC datasets. The experiments contrasted the accuracy of two machine learning classifiers (decision tree and logistic regression), trained with subsets of features generated either by single FS algorithms or the set of features selected by the ensemble feature selection framework. We observed that for the three datasets used (Sonar, SPECTF, and WD), the highest precision percentages (86.95%, 74.73%, and 93.85%, respectively) were obtained when the classifiers were trained with the subset of features generated by our framework. Additionally, the stability of the feature sets generated using our ensemble method was evaluated. The results showed that the method achieved perfect stability for the three datasets used in the evaluation.

Background: Previous studies have demonstrated the effectiveness of information and communication technologies to support healthy lifestyle interventions. In particular, personal health record systems (PHR-Ss) empower self-care, essential to support lifestyle changes. Approaches such as the user-centered design (UCD), which is already a standard within the software industry (ISO 9241-210:2010), provide specifications and guidelines to guarantee user acceptance and quality of eHealth systems. However, no single PHR-S for metabolic syndrome (MS) developed following the recommendations of the ISO 9241-210:2010 specification has been found in the literature. Objective: The aim of this study was to describe the development of a PHR-S for the management of MS according to the principles and recommendations of the ISO 9241-210 standard. Methods: The proposed PHR-S was developed using a formal software development process which, in addition to the traditional activities of any software process, included the principles and recommendations of the ISO 9241-210 standard. To gather user information, a survey sample of 1,187 individuals, eight interviews, and a focus group with seven people were performed. Throughout five iterations, three prototypes were built. Potential users of each system evaluated each prototype. The quality attributes of efficiency, effectiveness, and user satisfaction were assessed using metrics defined in the ISO/IEC 25022 standard. Results: The following results were obtained: 1) a technology profile from 1,187 ­individuals at risk for MS from the city of Popayan, Colombia, identifying that 75.2% of the people use the Internet and 51% had a smartphone; 2) a PHR-S to manage MS developed (the PHR-S has the ­following five main functionalities: record the five MS risk factors, share these measures with health care professionals, and three educational modules on nutrition, stress management, and a physical activity); and 3) usability tests on each prototype obtaining the following results: 100% effectiveness, 100% efficiency, and 84.2 points in the system usability scale. Conclusion: The software development methodology used was based on the ISO 9241‑210 ­standard, which allowed the development team to maintain a focus on user’s needs and requirements throughout the project, which resulted in an increased satisfaction and acceptance of the system. Additionally, the establishment of a multidisciplinary team allowed the application of considerations not only from the disciplines of software engineering and health sciences but also from other disciplines such as graphical design and media communication. Finally, usability testing allowed the observation of flaws in the designs, which helped to improve the solution.