The purpose of this study was to compare the efficacy of percutaneous aspiration thrombectomy (PAT) followed by standard anticoagulant therapy, with anticoagulation therapy alone, for the treatment of acute proximal lower extremity deep vein thrombosis. In this randomised, prospective study, 42 patients with acute proximal iliofemoral deep vein thrombosis documented via Doppler ultrasound examination, were separated into an interventional treatment group (16 males, 5 females, average age 51 years) and a medical treatment group (13 males, 8 females, average age 59 years). In the interventional group, PAT with large-lumen 9-F diameter catheterisation was applied, after initiation of standard anticoagulant therapy. Balloon angioplasty (n 19) and stent implementation (n: 14) were used to treat patients with residual stenosis (>50 %) after PAT. Prophylactic IVC filters were placed in two patients. The thrombus clearance status of the venous system was evaluated by venography. In both the medical and interventional groups, venous patency rates and clinical symptom scores were evaluated at months 1, 3, and 12 after treatment. Deep venous systems became totally cleared of thrombi in 12 patients treated with PAT. The venous patency rates in month 12 were 57.1 and 4.76 % in the interventional and medical treatment groups, respectively. A statistically significant improvement was observed in clinical symptom scores of the interventional group (PAT) with or without stenting (4.23 ± 0.51 before treatment; 0.81 ± 0.92 at month 12) compared with the medical treatment group (4.00 ± 0.63 before treatment; 2.43 ± 0.67 at month 12). During follow-up, four patients in the medical treatment and one in the interventional group developed pulmonary embolisms. For treatment of acute deep vein thrombosis, PAT with or without stenting is superior to anticoagulant therapy alone in terms of both ensuring venous patency and improving clinical symptoms. PAT is a safe, inexpensive, and easily performed method of endovascular treatment with a low rate of major complications. Our present findings and literature data suggest that PAT can be used as first-line treatment in proximal deep vein thrombosis patients, especially when thrombolytic treatment is contraindicated.

Conclusions: This study revealed that, in the adult population, the final diagnosis of this entity can only be made by combining imaging with clinical tests. Objective: We developed the largest temporal bone multislice computed tomography (CT) scan study so far by including 410 cases to investigate the prevalence of posterior semicircular canal dehiscence in patients with symptoms unrelated to the inner ear. Methods: A prospective study was performed in 410 consecutive adult individuals who underwent temporal bone multislice CT scan examinations. Results: The prevalence of posterior semicircular canal dehiscence was determined to be 1.2%. No superior or lateral semicircular canal defect was detected in these five patients. All cases with posterior semicircular canal defect were male. In two cases the canal was located unilaterally, while in three cases the defects were present bilaterally. Otological examination and audiovestibular tests revealed no abnormal findings in any of the individuals.

Background/aim: Hypoplastic left heart syndrome (HUTS) is a rare pathology with a very high mortality rate. The present study aimed to share our initial experience with the ductus arteriosus stenting procedure using the pulmonary trunk approach in the treatment of HLHS, as well as provide some technical suggestions and discuss complications and their management. Materials and methods: The medical records of 9 neonates (age range: 1-8 days) with HLHS, who were operated on within a 12-month period, were reviewed retrospectively. Preprocedural planning was performed by computed tomography angiography and echocardiography. The operations were performed in a hybrid surgery room by interventional radiologists and pediatric vascular surgeons. Balloon-expandable stents were used in all of the operations. Results: All operations were successfully completed without any intraoperative mortality. All intraoperative complications were managed successfully during the stenting procedure. Conclusion: Stage 1 hybrid palliation for HLHS is a safe and effective procedure when several key points are kept in mind.

Objectives: To investigate morphometric alterations associated with pediatric migraine without aura at the whole-brain, cerebellar subregional, and thalamic nuclei levels using a multiplatform magnetic resonance imaging (MRI) approach integrating the complementary strengths of different neuroimaging platforms. Methods: This retrospective study included 74 patients aged 12–17 years with migraine without aura and 70 control subjects with structurally normal cranial MRI findings. High-resolution isotropic three-dimensional T1-weighted MRI datasets were analyzed using a multiplatform segmentation workflow integrating vol2Brain, FreeSurfer, and 3D Slicer. Multiple comparisons were corrected using the Benjamini–Hochberg false discovery rate method. Significant volumetric measurements were subsequently normalized for total intracranial volume (TIV) and reanalyzed. Results: Compared with controls, patients with migraine exhibited lower bilateral amygdala and right thalamic volumes, as well as reduced cortical thickness in the right anterior insula, left anterior cingulate gyrus, and precuneus (all FDR-adjusted q < 0.05). Cerebellar analyses demonstrated reduced bilateral Lobule VI volume and gray matter volume, together with cortical thinning in the right Crus I and right Crus II (all FDR-adjusted q < 0.05). Thalamic nuclei analyses revealed lower volumes of the bilateral mediodorsal and pulvinar nuclei and the right ventral anterior and ventral posterolateral nuclei (all FDR-adjusted q < 0.05). All volumetric findings remained significant after TIV normalization. Conclusions: By integrating whole-brain morphometry with detailed cerebellar subregional and thalamic nuclei analyses, this study expands conventional morphometric assessment and provides a more integrated perspective on structural brain alterations associated with pediatric migraine without aura.