Many researchers worldwide have focused on the health impact of the coronavirus disease 2019 (COVID-19) pandemic without paying much emphasis to the environmental impacts associated with the pandemic. Evidence suggests that prior to the pandemic there was an alarming increase in environmental pollution due to rising industrialization, in particular in urban areas. Following the COVID-19 pandemic, satellite data over Asia and Europe showed a substantial decrease in air pollution, in particular nitrogen dioxide. However, the increase in industrial and household wastes may pose a significant challenge to environmental management. The improper management of these wastes poses an unforeseen “knock-on” effect on human health and the environment. It is imperative to establish an effective and safe procedure, for handling and disposing of the consequential wastes accumulating during the pandemic. The review aims to highlight both the beneficial and detrimental effects of COVID-19 pandemic on the natural environment and to discuss the possible strategies to improve the quality of the global environment during the period of the pandemic and beyond.

Lumpy Skin disease (LSD) is an economically important disease in cattle caused by the LSD virus (LSDV) of the genus Capripoxvirus, while pseudocowpox (PCP) is a widely distributed zoonotic cattle disease caused by the PCP virus (PCPV) of the genus Parapoxvirus. Though both viral pox infections are reportedly present in Nigeria, similarities in their clinical presentation and limited access to laboratories often lead to misdiagnosis in the field. This study investigated suspected LSD outbreaks in organized and transhumance cattle herds in Nigeria in 2020. A total of 42 scab/skin biopsy samples were collected from 16 outbreaks of suspected LSD in five northern States of Nigeria. The samples were analyzed using a high-resolution multiplex melting (HRM) assay to differentiate poxviruses belonging to Orthopoxvirus, Capripoxvirus, and Parapoxvirus genera. LSDV was characterized using four gene segments, namely the RNA polymerase 30 kDa subunit (RPO30), G-protein-coupled receptor (GPCR), the extracellular enveloped virus (EEV) glycoprotein and CaPV homolog of the variola virus B22R. Likewise, the partial B2L gene of PCPV was also analyzed. Nineteen samples (45.2%) were positive according to the HRM assay for LSDV, and five (11.9%) were co-infected with LSDV and PCPV. The multiple sequence alignments of the GPCR, EEV, and B22R showed 100% similarity among the Nigerian LSDV samples, unlike the RPO30 phylogeny, which showed two clusters. Some of the Nigerian LSDVs clustered within LSDV SG II were with commonly circulating LSDV field isolates in Africa, the Middle East, and Europe, while the remaining Nigerian LSDVs produced a unique sub-group. The B2L sequences of Nigerian PCPVs were 100% identical and clustered within the PCPV group containing cattle/Reindeer isolates, close to PCPVs from Zambia and Botswana. The results show the diversity of Nigerian LSDV strains. This paper also reports the first documented co-infection of LSDV and PCPV in Nigeria.

The aim of this study was to determine the trace minerals in the serum of goats in Zaria and its environs, and to find out the levels of lead and cadmium in the serum of these goats, so as to see if they can serve as biomonitors of pollution. A total of 120 goats were sampled from eight different locations randomly and their serum assayed for trace elements, lead and cadmium using the atomic absorption spectrometry (AAS). The values obtained were: lead 0.259 ± 0.470mg/L, cadmium 0.006 ± 0.004 mg/L, chromium 0.072 ± 0.064 mg/L, copper 0.089 ± 0.060 mg/L, iron 0.229 ± 0.180 mg/L, zinc 0.256 ± 0.266 mg/L, nickel 0.127 ± 0.086 mg/L, cobalt 0.135 ± 0.095 mg/L, manganese 0.042 ± 0.031 mg/L. Lead was above acceptable levels, cadmium was at acceptable levels, zinc, copper, iron and nickel were deficient, chromium was marginally deficient, while cobalt and manganese were normal. The effects of breed, sex, age and locations were generally not significant. The values obtained from lead is of public health significance, since these goats are sources of food to people in the immediate environment, and also this implies that people in the immediate environment are also exposed to the same sources of lead. There should be regular seromonitoring of blood lead levels in man and animals, and farmers should be enlightened on the need to augment the feeding of their animal with mineral supplements. Key words: Heavy metal; trace element; goat; lead; seromonitoring.

Rat hepatitis E virus (rHEV) is an emerging zoonotic pathogen, increasingly detected in human, animal, and environmental samples globally. Although rHEV shares the same subfamily as human hepatitis E virus (HEV; Paslahepevirus balayani), which is endemic across Africa, little is known about rHEV ecology on the continent beyond an isolated travel-related case linked to the Democratic Republic of Congo and Gabon. As a rodent-borne virus, rHEV poses a public health risk due to the widespread presence of the synanthropic reservoir Rattus norvegicus. Limited data on hepatitis of unknown origin further emphasise the need for active surveillance to understand the distribution, epidemiology, and impact of rHEV on human health. This review summarises our current knowledge on the global distribution of rHEV in humans, animals, and the environment, highlighting the importance of ongoing surveillance through the One Health Approach. Monitoring the virus in countries such as Nigeria, a country with a significant pig population and documented circulation of hepatitis E virus (HEV), could improve healthcare for immunocompromised and at-risk populations. Furthermore, the viral evolution may facilitate host adaptation and transmission, thereby complicating control efforts. These factors underscore the necessity for targeted research and intervention strategies to address the emerging threat of rHEV effectively.

Anemia and low haemoglobin levels are complications frequently associated with Sickle cell disease and beta-thalasssemia. Chemotherapy of these haemoglobinopathies involves the use of drugs which increase haemoglobin levels. The use of Terminalia catappa traditionally for the treatment of SCD dates back. Herein we evaluated the potential of Terminalia catappa to induce erythropoiesis in adult Balb C mice. The methanolic extract of Terminalia catappa induced production of haemoglobin higher than that of an untreated control after 6 days. The PCV of treated and untreated mice was also assessed and found to be relatively higher in Terminalia catappa treated mice comparable to mice administered with folic acid.