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Contemporary cities could be considered vibrant organisms of places and communities, of data and information, of sensors and actuators, and of actions and reactions generated by people and environment both. Cities must be more responsive to our behavioral changes, enabling devices for enhancing our contemporary life. We would be able to build a more efficient urban environment, able to sense, to understand and to act every day and for everyone. In the post-city age and beyond the smart city, Augmented City is a new paradigm that perceives the demands of more networked, knowledge-based, and creative society that answers to the global change by a new circular metabolism. The Augmented City is a spatial/cultural/social/economic platform for enhancing our contemporary life, individual and collective, informal, and institutional, expanding the urban space generated by the effects of innovation. The Augmented City redefines dogmas of urbanism that we often thought of being more static and rule-based, recovering its prospective, incremental, responsive, and creative approach. We need to think, design, and manage cities more sentient, open source and intelligent, again productive, creative and based on recycle, cities resilient, fluid and reticular, and truly strategic. The Augmented City is not the city of the future, but it brings us in a different present.
Maurizio Carta. Augmented Cities in the Neoanthropocene. Current Challenges in Architecture and Urbanism in Albania 2021, 19 -29.
AMA StyleMaurizio Carta. Augmented Cities in the Neoanthropocene. Current Challenges in Architecture and Urbanism in Albania. 2021; ():19-29.
Chicago/Turabian StyleMaurizio Carta. 2021. "Augmented Cities in the Neoanthropocene." Current Challenges in Architecture and Urbanism in Albania , no. : 19-29.
When Covid-19 arrived in Europe from the far East, the media and experts in economics and social sciences noticed that it was the expected discontinuity in the socio-economic development process. Really, the current phase has spread since the 1960s, when the application of econometric worldwide-spread development model was going to produce social inequalities, and consumption of physical, social, and cultural resources. Some places in Italy, far from the erosive and urban context and erosive metropolitan areas, are currently isolated seeds of a new cycle of life, because of the local community identity and the strong link between human, cultural, and natural components are currently working together towards a new development model. Starting from a 20-year research about Local Cultural Systems in Sicily, the research group has defined and tested the cultural dimension of development, and affirmed that the transition to a culture-based growth, as defined by UNESCO, should be the solution for overcoming the erosive Anthropocene era. In western Sicily, the Belice Valley is working on cultural transition thanks to relationships between cultural heritage, identity, and settlement network, that we have designed as a Territorial Archipelago. The research demonstrates that local communities will innovate if they rethink the development model and reshape spatial patterns and economic networks focusing on the creativity-driven vision.
Maurizio Carta; Daniele Ronsivalle; Barbara Lino. Inner Archipelagos in Sicily. From Culture-Based Development to Creativity-Oriented Evolution. Sustainability 2020, 12, 7452 .
AMA StyleMaurizio Carta, Daniele Ronsivalle, Barbara Lino. Inner Archipelagos in Sicily. From Culture-Based Development to Creativity-Oriented Evolution. Sustainability. 2020; 12 (18):7452.
Chicago/Turabian StyleMaurizio Carta; Daniele Ronsivalle; Barbara Lino. 2020. "Inner Archipelagos in Sicily. From Culture-Based Development to Creativity-Oriented Evolution." Sustainability 12, no. 18: 7452.
Analyzing the human history on the planet, a conflictual relation was raised when humankind had started destroying the natural ecosystem and biota, and consequently, a capacity to induce environmental change has increased throughout human history in the so-called Anthropocene age. A ‘noosphere’-centered civilization could produce a non-disruptive new kind of anthropocentrism. This is becoming a new context to define Neoanthropocene based on a renewed homeostatic relationship between Earth and mankind. The potential application of this theoretical approach has been tested in drafting steps of Plan of Lucania Apennines, Valdagri, and Lagonegrese National Park, in southern Italy. Drafting the plan, the authors have applied a strategic approach based on environmental and cultural evidence and have drafted an interpretation plan for local growth, consistent with local resources. The result is a plan, shared with local stakeholders, in which the authors have proposed a multisectoral development plan based on a ‘cluster approach’ for regeneration: The main wild areas are reached through a visitor center or similar introducing facilities, and they are connected with historical centers, archaeological parks, ski areas, accommodation facilities, and other local services. The expected effect is the growth in number of chances to develop business in accordance with environment protection duty.
Maurizio Carta; Daniele Ronsivalle. Neoanthropocene Raising and Protection of Natural and Cultural Heritage: A Case Study in Southern Italy. Sustainability 2020, 12, 4186 .
AMA StyleMaurizio Carta, Daniele Ronsivalle. Neoanthropocene Raising and Protection of Natural and Cultural Heritage: A Case Study in Southern Italy. Sustainability. 2020; 12 (10):4186.
Chicago/Turabian StyleMaurizio Carta; Daniele Ronsivalle. 2020. "Neoanthropocene Raising and Protection of Natural and Cultural Heritage: A Case Study in Southern Italy." Sustainability 12, no. 10: 4186.
Maurizio Carta; Barbara Lino; Marilena Orlando. Innovazione sociale e creatività. Nuovi scenari di sviluppo per il territorio sicano. ARCHIVIO DI STUDI URBANI E REGIONALI 2018, 140 -162.
AMA StyleMaurizio Carta, Barbara Lino, Marilena Orlando. Innovazione sociale e creatività. Nuovi scenari di sviluppo per il territorio sicano. ARCHIVIO DI STUDI URBANI E REGIONALI. 2018; (123):140-162.
Chicago/Turabian StyleMaurizio Carta; Barbara Lino; Marilena Orlando. 2018. "Innovazione sociale e creatività. Nuovi scenari di sviluppo per il territorio sicano." ARCHIVIO DI STUDI URBANI E REGIONALI , no. 123: 140-162.
Valeria Seidita; Antonio Chella; Maurizio Carta. Capturing citizens — Emerging needs: Using social networks in smart cities. 2017 AEIT International Annual Conference 2017, 1 .
AMA StyleValeria Seidita, Antonio Chella, Maurizio Carta. Capturing citizens — Emerging needs: Using social networks in smart cities. 2017 AEIT International Annual Conference. 2017; ():1.
Chicago/Turabian StyleValeria Seidita; Antonio Chella; Maurizio Carta. 2017. "Capturing citizens — Emerging needs: Using social networks in smart cities." 2017 AEIT International Annual Conference , no. : 1.
Background: Fermented foods have been proposed to prevent common infectious diseases (CIDs) in children attending day care or preschool. Objectives: To investigate the efficacy of dietary supplementation with cow’s skim milk fermented with the probiotic Lactobacillus paracasei CBA L74 in reducing CIDs in children attending day care or preschool. Methods: Multicenter, randomized, double-blind, placebo-controlled trial on healthy children (aged 12–48 months) consuming daily 7 grams of cow’s skim milk fermented with L. paracasei CBA L74 (group A), or placebo (maltodextrins group B) attending day care or preschool during the winter season. The main outcome was the proportion of children who experienced ≥1 episode of CID during a 3-month follow-up. Fecal biomarkers of innate (α- and β-defensins, cathelicidin) and acquired immunity (secretory IgA) were also monitored. Results: A total of 126 children (71 males, 56%) with a mean (SD) age of 33 (9) months completed the study, 66 in group A and 60 in group B. At intention to treat analysis, the proportion of children presenting ≥1 CID was 60% in group A vs. 83% in group B, corresponding to an absolute risk difference (ARD) of −23% (95% CI: −37% to −9%, p < 0.01). At per-protocol-analysis (PPA), the proportion of children presenting ≥1 CID was 18% in group A vs. 40% in group B, corresponding to an absolute risk difference (ARD) of −22% (95% CI: −37% to −6%, p < 0.01). PPA showed that the proportion of children presenting ≥1 acute gastroenteritis (AGE) was significantly lower in group A (18% vs. 40%, p < 0.05). The ARD for the occurrence of ≥1 AGE was −22% (95% CI: −37% to −6%, p < 0.01) in group A. Similar findings were obtained at PPA regarding the proportion of children presenting ≥1 upper respiratory tract infection (URTI), which was significantly lower in group A (51% vs. 74%, p < 0.05), corresponding to an ARD of −23% (95% CI: −40% to −7%, p < 0.01). Significant changes in innate and acquired immunity biomarkers were observed only in subjects in group A. Conclusions: Dietary supplementation with cow’s skim milk fermented with L. paracasei CBA L74 is an efficient strategy in preventing CIDs in children.
Giovanni Corsello; Maurizio Carta; Roberto Marinello; Marina Picca; Giulio De Marco; Maria Micillo; Dante Ferrara; Patrizia Vigneri; Gaetano Cecere; Pasqualina Ferri; Paola Roggero; Giorgio Bedogni; Fabio Mosca; Lorella Paparo; Rita Nocerino; Roberto Berni Canani. Preventive Effect of Cow’s Milk Fermented with Lactobacillus paracasei CBA L74 on Common Infectious Diseases in Children: A Multicenter Randomized Controlled Trial. Nutrients 2017, 9, 669 .
AMA StyleGiovanni Corsello, Maurizio Carta, Roberto Marinello, Marina Picca, Giulio De Marco, Maria Micillo, Dante Ferrara, Patrizia Vigneri, Gaetano Cecere, Pasqualina Ferri, Paola Roggero, Giorgio Bedogni, Fabio Mosca, Lorella Paparo, Rita Nocerino, Roberto Berni Canani. Preventive Effect of Cow’s Milk Fermented with Lactobacillus paracasei CBA L74 on Common Infectious Diseases in Children: A Multicenter Randomized Controlled Trial. Nutrients. 2017; 9 (7):669.
Chicago/Turabian StyleGiovanni Corsello; Maurizio Carta; Roberto Marinello; Marina Picca; Giulio De Marco; Maria Micillo; Dante Ferrara; Patrizia Vigneri; Gaetano Cecere; Pasqualina Ferri; Paola Roggero; Giorgio Bedogni; Fabio Mosca; Lorella Paparo; Rita Nocerino; Roberto Berni Canani. 2017. "Preventive Effect of Cow’s Milk Fermented with Lactobacillus paracasei CBA L74 on Common Infectious Diseases in Children: A Multicenter Randomized Controlled Trial." Nutrients 9, no. 7: 669.
Valeria Seidita; Antonio Chella; Maurizio Carta. A Biologically Inspired Representation of the Intelligence of a University Campus. Procedia Computer Science 2016, 88, 185 -190.
AMA StyleValeria Seidita, Antonio Chella, Maurizio Carta. A Biologically Inspired Representation of the Intelligence of a University Campus. Procedia Computer Science. 2016; 88 ():185-190.
Chicago/Turabian StyleValeria Seidita; Antonio Chella; Maurizio Carta. 2016. "A Biologically Inspired Representation of the Intelligence of a University Campus." Procedia Computer Science 88, no. : 185-190.
The “Smart Cities & Communities Initiative” of the Strategic Energy Technology Plan is the strategic European response to lead cities and regions to a carbon free future. In this contest energy efficiency in buildings has a crucial role and must be considered in a holistic approach to the urban planning. In order to implement the minimum requirements stated by the European Directive about the Energy Performance of Buildings, and in order to consider different planning layers with the view to a smart city planning, local regulations are a key factor aiming at sustainable territorial planning. This paper investigates the possibility to draft a basic structure of Municipal Building Regulations in order to guide local administrators and technicians and to limit discretionary power of bureaucracy. The paper is organized as follows. First, a review of the most common practices for building regulations in Europe is proposed, then the basic structure of a municipal building regulation for the city of Palermo (Southern Italy) accounting for sustainability is discussed.
Eleonora Riva Sanseverino; Gianluca Scaccianoce; Valentina Vaccaro; Maurizio Carta; Raffaella Riva Sanseverino. Smart Cities and Municipal Building Regulation for Energy Efficiency. International Journal of Agricultural and Environmental Information Systems 2015, 6, 56 -82.
AMA StyleEleonora Riva Sanseverino, Gianluca Scaccianoce, Valentina Vaccaro, Maurizio Carta, Raffaella Riva Sanseverino. Smart Cities and Municipal Building Regulation for Energy Efficiency. International Journal of Agricultural and Environmental Information Systems. 2015; 6 (4):56-82.
Chicago/Turabian StyleEleonora Riva Sanseverino; Gianluca Scaccianoce; Valentina Vaccaro; Maurizio Carta; Raffaella Riva Sanseverino. 2015. "Smart Cities and Municipal Building Regulation for Energy Efficiency." International Journal of Agricultural and Environmental Information Systems 6, no. 4: 56-82.
We live in the society of knowledge, creativity and innovation: true anti-cyclical factors with respect to the crisis that has overrun the traditional development protocols and that requires powerful processes of creation and spread of knowledge. The true innovation has no boundaries, it has to affect each aspect of institutions and enterprises and operates as a mutagen of society, requiring a paradigm shift. Startups, fablabs, co-workers, makers and smart citizens have given rise to a global urban movement and most cities now have a sizeable colony: a true smart ecosystem for improving social innovation. Between them they are home to hundreds of accelerators and thousands of smart places and co-working spaces, and this ecosystem must be highly interconnected and integrated in a renewed urban metabolism driven by more adequate planning paradigms and tools. The combination of technological innovation and urban planning, however, is not only instrumental and determines changes within the community and its territory too. The “Third Industrial Revolution” and the gradual implementation of e-society have made it possible to delegate an increasing number of physical and intellectual tasks, even very sophisticated, to technology. In fact, the goods and ideas produced are increasingly less tied to a scheduled place and time, in terms of quality and quantity; the workplace is no longer an independent variable and time is no longer rigidly synchronized, especially as far as the intellectual work is concerned. The spreading of sensors, smart devices, electronic networks and urban life apps has created a proper urban cyber-physical space, consisting of the constant interaction between physical components and digital networks, tangible actions and intangible feedback. Smart cities are components of a new urban organism able to rethink the development and to encourage a “creative explosion”, leading smartness-based initiatives as part of a European post-metropolitan vision.
Maurizio Carta. Smart Planning and Intelligent Cities: A New Cambrian Explosion. Sxi — Springer per l’Innovazione / Sxi — Springer for Innovation 2014, 123 -132.
AMA StyleMaurizio Carta. Smart Planning and Intelligent Cities: A New Cambrian Explosion. Sxi — Springer per l’Innovazione / Sxi — Springer for Innovation. 2014; ():123-132.
Chicago/Turabian StyleMaurizio Carta. 2014. "Smart Planning and Intelligent Cities: A New Cambrian Explosion." Sxi — Springer per l’Innovazione / Sxi — Springer for Innovation , no. : 123-132.
Dante Ferrara; Maurizio Carta. Strategie di prevenzione dell’aterosclerosi in età pediatrica. Area Pediatrica 2012, 13, 43 -47.
AMA StyleDante Ferrara, Maurizio Carta. Strategie di prevenzione dell’aterosclerosi in età pediatrica. Area Pediatrica. 2012; 13 (2):43-47.
Chicago/Turabian StyleDante Ferrara; Maurizio Carta. 2012. "Strategie di prevenzione dell’aterosclerosi in età pediatrica." Area Pediatrica 13, no. 2: 43-47.
La città è eminentemente “enciclopedia” della comunità, luogo in cui si ritrovano tutte le componenti della vita umana, la loro definizione ma anche i loro rapporti reciproci(Harvey 1989). Nel secolo urbano in cui siamo immersi, la città da enciclopedia si evolve in quella che l’autore definisce una “wikipedia urbana”: cioè un’opera cognitiva collettiva in cui gli abitanti e gli utilizzatori, i decisori e gli attori, i progettisti e gli attuatori compongono la struttura arricchendola continuamente con l’evoluzione degli usi, con l’interpretazione dei significati, con le volontà delle intenzioni. Per comporre, comprendere, rappresentare e trasmettere la wikipedia urbana, la sua stratificazione cronologica e la sua rugosità spaziale, la sua armonia architettonica ma spesso anche la sua dissonanza sociale, abbiamo necessità di costruire una nuova epistemologia che sia capace di valutare ed utilizzare la molteplicità delle identità territoriali e che sappia attivare nuove forme progettuali.
Maurizio Carta. Per una wikipedia urbana: sfide del progetto urbanistico. 2011, 69 -80.
AMA StyleMaurizio Carta. Per una wikipedia urbana: sfide del progetto urbanistico. . 2011; ():69-80.
Chicago/Turabian StyleMaurizio Carta. 2011. "Per una wikipedia urbana: sfide del progetto urbanistico." , no. : 69-80.
The network of European Union creative cities is a powerful new configuration of dynamic, innovative and action-oriented cities, able to transform the space using their network of cultural heritage and activities. From a vision in which the more competitive cities are those able to attract the creative class must go to a vision in which the city becomes generates creativity, presents itself as a powerful incubator of economies based on creativity, culture, research and artistic production. The cities will have to invest in the experience economy, strengthening their identity. The Creative City 3.0, therefore, is an active tension, that requires a long-term vision ability, and calls us to action. A creative city offers some relevant resources for city councils, planners, architects and designers, an indispensable guide towards innovation and quality production, balancing free enterprise and initiative and contributing to the overall happiness of the communities they seek to serve.
Maurizio Carta. Culture, communication and cooperation: the three Cs for a proactive creative city. International Journal of Sustainable Development 2009, 12, 124 .
AMA StyleMaurizio Carta. Culture, communication and cooperation: the three Cs for a proactive creative city. International Journal of Sustainable Development. 2009; 12 (2/3/4):124.
Chicago/Turabian StyleMaurizio Carta. 2009. "Culture, communication and cooperation: the three Cs for a proactive creative city." International Journal of Sustainable Development 12, no. 2/3/4: 124.
Prenatal exposure to antiepileptic drugs (AEDs) increases the risk of major congenital malformations (MCM) in the fetus. AED-related abnormalities include heart and neural tube defects, cleft palate, and urogenital abnormalities. Among the various congenital anomalies of the kidney and urinary tract (CAKUT), multicystic dysplastic kidney (MCDK) disease is one of the most severe expressions. Although prenatal ultrasound (US) examination has increased the prenatal diagnosis of MCDK, the pathogenesis is still unclear. We report on four cases of MCDK in infants of epileptic women treated with AEDs during pregnancy. From October 2003 to June 2006, we observed four infants with unilateral MCDK born to epileptic women. Three patients were considered to have typical features of multicystic dysplastic kidney, and one infant was operated because of a cystic pelvic mass in the absence of a kidney in the left flank. The macroscopic appearance of this mass showed an ectopic multicystic kidney confirmed by histological findings. All patients have been studied by US scans, voiding cystourethrogram (VCUG), and radionuclide screening isotope imaging. The prenatal exposure to AEDs increases the risk of major congenital malformations from the background risk of 1-2% to 4-9%. AEDs may determine a defect in apoptosis regulation that could lead to abnormal nephrogenesis, causing MCDK. Carbamazepine (CBZ) and phenobarbital (PHB) during pregnancy should be used at the lowest dosage compatible with maternal disease. The reduction, or even suspension, of drug dosage should be achieved from the periconceptional period to the first 8 weeks of gestation to avoid any interference with organogenesis.
Maurizio Carta; Marcello Cimador; Mario Giuffrè; Maria Sergio; Maria Rita DI Pace; Enrico De Grazia; Giovanni Corsello. Unilateral multicystic dysplastic kidney in infants exposed to antiepileptic drugs during pregnancy. Pediatric Nephrology 2007, 22, 1054 -1057.
AMA StyleMaurizio Carta, Marcello Cimador, Mario Giuffrè, Maria Sergio, Maria Rita DI Pace, Enrico De Grazia, Giovanni Corsello. Unilateral multicystic dysplastic kidney in infants exposed to antiepileptic drugs during pregnancy. Pediatric Nephrology. 2007; 22 (7):1054-1057.
Chicago/Turabian StyleMaurizio Carta; Marcello Cimador; Mario Giuffrè; Maria Sergio; Maria Rita DI Pace; Enrico De Grazia; Giovanni Corsello. 2007. "Unilateral multicystic dysplastic kidney in infants exposed to antiepileptic drugs during pregnancy." Pediatric Nephrology 22, no. 7: 1054-1057.
Marcello Cimador; Maurizio Carta; Maria Rita DI Pace; Gianfranco Natale; A Castiglione; Maria Sergio; G Corsello; E De Grazia. Primary repair in esophageal atresia. The results of long term follow-up. Minerva Pediatrica 2006, 58, 9 -13.
AMA StyleMarcello Cimador, Maurizio Carta, Maria Rita DI Pace, Gianfranco Natale, A Castiglione, Maria Sergio, G Corsello, E De Grazia. Primary repair in esophageal atresia. The results of long term follow-up. Minerva Pediatrica. 2006; 58 (1):9-13.
Chicago/Turabian StyleMarcello Cimador; Maurizio Carta; Maria Rita DI Pace; Gianfranco Natale; A Castiglione; Maria Sergio; G Corsello; E De Grazia. 2006. "Primary repair in esophageal atresia. The results of long term follow-up." Minerva Pediatrica 58, no. 1: 9-13.
A newborn with an unusual association of hepatic mesenchymal hamartoma and mesenchymal stem villous hyperplasia of the placenta is presented. At birth, the large hepatic mass caused severe respiratory distress necessitating early surgical intervention. This report on the association of hepatic mesenchymal hamartoma and mesenchymal stem villous hyperplasia of the placenta strongly suggests a common pathogenetic origin of the 2 lesions.
Maurizio Carta; Emiliano Maresi; Mario Giuffrè; Giuseppe Catalano; Ettore Piro; Fortunato Siracusa; Giovanni Corsello. Congenital hepatic mesenchymal hamartoma associated with mesenchymal stem villous hyperplasia of the placenta: case report. Journal of Pediatric Surgery 2005, 40, e37 -e39.
AMA StyleMaurizio Carta, Emiliano Maresi, Mario Giuffrè, Giuseppe Catalano, Ettore Piro, Fortunato Siracusa, Giovanni Corsello. Congenital hepatic mesenchymal hamartoma associated with mesenchymal stem villous hyperplasia of the placenta: case report. Journal of Pediatric Surgery. 2005; 40 (5):e37-e39.
Chicago/Turabian StyleMaurizio Carta; Emiliano Maresi; Mario Giuffrè; Giuseppe Catalano; Ettore Piro; Fortunato Siracusa; Giovanni Corsello. 2005. "Congenital hepatic mesenchymal hamartoma associated with mesenchymal stem villous hyperplasia of the placenta: case report." Journal of Pediatric Surgery 40, no. 5: e37-e39.
We report a newborn girl with a de novo terminal 4q deletion (q31.3 → qter) and a characteristic phenotype of minor facial anomalies, cleft palate, congenital heart defect, abnormalities of hands and feet, and postnatal onset of growth deficiency. Laboratory studies showed excessive urinary calcium excretion on standard milk formula and on oral calcium load. Blood measurements of parathyroid hormone, calcitonin, bicarbonate, calcium, phosphorus, magnesium, sodium, chlorine, potassium, and urinary measurements of phosphorus, magnesium, sodium, chlorine, potassium were normal for age. At 2 months of life, ultrasonography showed kidney calcifications. Clinical and laboratory data support the diagnosis of absorptive hypercalciuria or abnormal regulation of calcium‐sensing receptors in the renal tubules. The evidence of hypercalciuria and kidney calcifications associated with 4q terminal deletion strengthens the hypothesis that a putative gene for hypercalciuria is located on the terminal segment of chromosome 4q.
Mario Giuffrè; Simona La Placa; Maurizio Carta; Antonella Cataliotti; Maria Marino; Maria Piccione; Francesco Pusateri; Ferdinando Meli; Giovanni Corsello. Hypercalciuria and kidney calcifications in terminal 4q deletion syndrome: Further evidence for a putative gene on 4q. American Journal of Medical Genetics Part A 2003, 126A, 186 -190.
AMA StyleMario Giuffrè, Simona La Placa, Maurizio Carta, Antonella Cataliotti, Maria Marino, Maria Piccione, Francesco Pusateri, Ferdinando Meli, Giovanni Corsello. Hypercalciuria and kidney calcifications in terminal 4q deletion syndrome: Further evidence for a putative gene on 4q. American Journal of Medical Genetics Part A. 2003; 126A (2):186-190.
Chicago/Turabian StyleMario Giuffrè; Simona La Placa; Maurizio Carta; Antonella Cataliotti; Maria Marino; Maria Piccione; Francesco Pusateri; Ferdinando Meli; Giovanni Corsello. 2003. "Hypercalciuria and kidney calcifications in terminal 4q deletion syndrome: Further evidence for a putative gene on 4q." American Journal of Medical Genetics Part A 126A, no. 2: 186-190.
The purpose of the present study was to assess the presence and the time-course of contrast-enhancement in the pituitary gland and pituitary stalk of 24 patients with isolated growth hormone (GH) deficiency and multiple pituitary hormone deficiency. The patients were evaluated clinically (auxological measurements), endocrinologically (spontaneous GH secretion and GH stimulation tests) and with conventional MRI scans. In addition, fast-framing dynamic magnetic resonance imaging (MRI) with Gd-DTPA enhancement was used to quantitate the time course of contrast enhancement within the neurohypophysis, pituitary stalk, postero-superior adenohypophysis and antero-inferior adenohypophysis. In 3 patients without evidence of abnormalities at normal conventional MRI scans (normal anterior lobe and pituitary stalk, normal posterior lobe) and a high response to the GRF provocation test, sequential time-resolved Gd-enhanced MRI demonstrates reduced contrast enhancement in the pituitary stalk. These findings are consistent with impairment in stalk vasculature, presumably located at the level of the portal venous system, and could play a role in the pathogenesis of pituitary hormonal deficiency.
A. Liotta; C. Maggio; M. Giuffrè; Maurizio Carta; L. Manfrè. Sequential contrast-enhanced magnetic resonance imaging in the diagnosis of growth hormone deficiencies. Journal of Endocrinological Investigation 1999, 22, 740 -746.
AMA StyleA. Liotta, C. Maggio, M. Giuffrè, Maurizio Carta, L. Manfrè. Sequential contrast-enhanced magnetic resonance imaging in the diagnosis of growth hormone deficiencies. Journal of Endocrinological Investigation. 1999; 22 (10):740-746.
Chicago/Turabian StyleA. Liotta; C. Maggio; M. Giuffrè; Maurizio Carta; L. Manfrè. 1999. "Sequential contrast-enhanced magnetic resonance imaging in the diagnosis of growth hormone deficiencies." Journal of Endocrinological Investigation 22, no. 10: 740-746.