Christina Hardesty

Dr. Christina Hardesty

orcid

Research Focus & Metrics

Academic Career Length

9Years (2018-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 July 2018 in Spine Deformity
Verified
Journal Article
Closed access
CHChristina Hardesty
Christina Hardesty
RHRobert P. Huang
Robert P. Huang
RERon El-Hawary
Ron El-Hawary
ASAmer Samdani
Amer Samdani
PHPaloma Bas Hermida
Paloma Bas Hermida
SLScott Luhmann
Scott Luhmann

1 February 2018 in Journal of Pediatric Orthopaedics
Verified
Journal Article
Closed access
CHChristina Hardesty
Christina Hardesty
ZGZachary L. Gordon
Zachary L. Gordon
CPConnie Poe-Kochert
Connie Poe-Kochert
JSJochen P. Son-Hing
Jochen P. Son-Hing
GTGeorge H. Thompson
George H. Thompson
Background: Reducing perioperative blood loss and the need for transfusions in patients undergoing spinal surgery is especially important for those with neuromuscular disorders. These patients require extensive spino-pelvic exposure and are often medically fragile. We have used Amicar to decrease blood loss since 2001. As an effort to further reduce blood loss and transfusions, we use a bipolar sealer device (Aquamantys) as an adjunct to electrocautery. We present the results of our first 64 neuromuscular patients to show the efficacy of the device. Methods: Using a prospectively maintained database we reviewed the operative time, estimated perioperative blood loss, cell saver use, and intraoperative and postoperative transfusion rate in patients who underwent posterior spinal fusion for neuromuscular scoliosis. Sixty-four patients were identified who fit these criteria since the use of the bipolar sealer device was instituted.We compared these patients with a control group of the preceding 65 patients in whom this device was not used for hemostasis. All patients, including those in the study group, received Amicar (infusion of 100 mg/kg over 15 to 20 min, then 10 mg/kg/h throughout the remainder of the procedure). The surgical technique did not differ between the 2 groups. Results: Baseline characteristics between the 2 groups were similar except for the number of patients having an all-screw construct which was larger in the investigational group (25% vs. 8%, P=0.03). There were no significant differences in operative time or duration of hospital stay. Intraoperative blood loss was lower in the study group (741 mL) as compared with the control group (1052 mL, P=0.003). Total perioperative blood loss, however, showed no significant difference. Thirty-five (55%) patients in the study group and 50 (77%) patients in the control group required additional intraoperative or postoperative transfusions (P=0.01). The number of packed red cell units transfused per patient was 0.81 in the study group and 1.57 in the control group (P=0.001). Although the intraoperative cell saver transfusion was same, the total blood volume transfused, which includes cell saver and any other transfusions, was significantly lower in the study group, 425 mL versus 671 mL (P=0.002). Conclusions: Use of a bipolar sealer device in posterior spinal fusion for neuromuscular scoliosis significantly reduced intraoperative blood loss and transfusion rate when compared with a control group in this retrospective review. Level of Evidence: Level III—retrospective comparative study.

21 July 2020 in Journal of Bone and Joint Surgery
Verified
Journal Article
Closed access
JDJerry Du
Jerry Du
CPConnie Poe-Kochert
Connie Poe-Kochert
GTGeorge H. Thompson
George H. Thompson
CHChristina Hardesty
Christina Hardesty
JPJeff B. Pawelek
Jeff B. Pawelek
PGPediatric Spine Study Group
Pediatric Spine Study Group
Background: Although there is a high rate of reoperation after final fusion following the treatment of early-onset scoliosis with use of traditional growing rods, the risk factors for reoperation are unknown. The purpose of the present study was to identify risk factors associated with the need for reoperation after final fusion for the treatment of early-onset scoliosis. Methods: A multicenter database for patients with early-onset scoliosis was retrospectively analyzed. Patients managed with traditional growing rods and final fusion were identified (n = 248). The inclusion criteria were ≥1 lengthening procedure with traditional growing rods and ≥2 years of follow-up after final fusion or revision surgery within 2 years after final fusion (167 patients; 67%). Patients requiring reoperation following final fusion were compared with patients who did not require reoperation. The data that were analyzed included demographic characteristics, comorbidities, spinal deformity characteristics, radiographic measurements, perioperative details, and complications during all stages of treatment. A multivariate regression model was used to identify independent risk factors. Results: The mean duration of follow-up from the initial visit to the latest visit was 10.7 ± 4.1 years, and the mean duration of follow-up after final fusion was 4.9 ± 3.1 years. Thirty-two (19%) of the 167 patients required reoperation following final fusion. Curve progression requiring revision surgery during lengthening with traditional growing rods (adjusted odds ratio [aOR], 21.137 per event; p = 0.028), the number of levels spanned with traditional growing rods (aOR, 1.378 per level; p = 0.007), and the duration of treatment with traditional growing rods (aOR, 1.220 per year; p = 0.035) were independently associated with revision surgery after final fusion. Conclusions: Independent risk factors for curve progression requiring reoperation during lengthening with traditional growing rods that require operative intervention include increasing number of levels spanned with traditional growing rods and longer duration of treatment with traditional growing rods. These findings may help with patient counseling and potentially guide surgeon decision-making. Level of Evidence: Prognostic Level IV. See Instructions for Authors for a complete description of levels of evidence.

30 November 2020 in Spine Deformity
Verified
Journal Article
Closed access
PDF file
TGThe Pediatric Spine Study Group
The Pediatric Spine Study Group
CHChristina Hardesty
Christina Hardesty
RMRobert F. Murphy
Robert F. Murphy
JPJeff B. Pawelek
Jeff B. Pawelek
MGMichael P. Glotzbecker
Michael P. Glotzbecker
BABehrooz A. Akbarnia
Behrooz A. Akbarnia

7 July 2023 in Journal of Pediatric Orthopaedics
Verified
Journal Article
Closed access
ACAugust A. Ba Culbert
August A. Ba Culbert
BRBryan O. Ren
Bryan O. Ren
BMBhargavi Maheshwer
Bhargavi Maheshwer
ACAndrew Curtis
Andrew Curtis
JAJayakrishnan Ajayakumar
Jayakrishnan Ajayakumar
MGMichael P. Glotzbecker
Michael P. Glotzbecker
Background: The COVID-19 pandemic has led to significant disruptions in medical care, resulting in an estimated 40% of US adults avoiding care. However, the return to baseline health care utilization following COVID-19 restrictions within the pediatric orthopedic population remains unexplored. We sought to analyze the visit volume and demographics of pediatric orthopedic patients at 3 timepoints: prepandemic (2019), pandemic (2020), and pandemic post-vaccine availability (2021), to determine the impact of COVID-19 restrictions on our single-center, multisite institution. Methods: We performed a retrospective cohort study of 6318 patients seeking treatment at our institution from May through August in 2019, 2020, and 2021. Patient age, sex, address, encounter date, and ICD-10 codes were obtained. Diagnoses were classified into fractures and dislocations, non–fracture-related trauma, sports, elective, and other categories. Geospatial analysis comparing incidence and geospatial distribution of diagnoses across the time periods was performed and compared with the Centers for Disease Control (CDC) social vulnerability index (SVI). Results: The total number of pediatric orthopedic visits decreased by 22.2% during the pandemic (P<0.001) and remained 11.6% lower post-vaccine availability compared with prepandemic numbers (P<0.001). There was no significant difference in age (P=0.097) or sex (P=0.248) of the patients across all 3 timepoints; however, patients seen during the pandemic were more often White race (67.7% vs. 59.3%, P<0.001). Post-vaccine availability, trauma visits increased by 18.2% (P<0.001) and total fractures remained 13.4% lower than prepandemic volume (P<0.001). Sports volume decreased during the pandemic but returned to prepandemic volume in the post-vaccine availability period (P=0.298). Elective visits did not recover to prepandemic volume and remained 13.0% lower compared with baseline (P<0.001). Geospatial analysis of patient distribution illustrated neighborhood trends in access to care during the COVID-19 pandemic, with fewer patients from high SVI and low socioeconomic status neighborhoods seeking fracture care during the pandemic than prepandemic. Post-vaccine availability, fracture population distribution resembled prepandemic levels, suggesting a return to baseline health care utilization. Conclusion: Pediatric orthopedic surgery visit volume broadly decreased during the COVID-19 pandemic and did not return to prepandemic levels. All categories increased in the post-vaccine availability time point except elective visits. Geospatial analysis revealed that neighborhoods with a high social vulnerability index (SVI) were associated with decreased fracture visits during the pandemic, whereas low SVI neighborhoods did not experience as much of a decline. Future research is needed to study these neighborhood trends and more completely characterize factors preventing equitable access to care in the pediatric orthopedic population. Level of Evidence: Retrospective Study, Level III.

1 July 2019 in Journal of Pediatric Orthopaedics B
Verified
Journal Article
Closed access
MAMatthew V. Abola
Matthew V. Abola
CHChristina Hardesty
Christina Hardesty
DKDerrick M. Knapik
Derrick M. Knapik
CPConnie Poe-Kochert
Connie Poe-Kochert
JSJochen P. Son-Hing
Jochen P. Son-Hing
GTGeorge H. Thompson
George H. Thompson
The aim of this study was to define the incidence of complete implant removal following surgical correction of spinal deformity in pediatric patients over a 22-year period and identify possible risk factors. A retrospective review of our Pediatric Orthopedic Spine Database between 1992 and 2016 was performed. We included patients undergoing complete implant removal following scoliosis correction surgery with a minimum of 2-year follow-up. Medical charts were reviewed to determine initial patient diagnosis and the indication for implant removal. Statistical analysis was carried out to determine the associations between sex and factors such as primary diagnosis and indication for removal. A review of 1117 procedures in 1114 patients identified complete instrument removal in 52 (4.7%) patients (34 females and 18 males). Mean time to removal following surgery was 2.3 years (range: 0–5.9 years). Removal occurred in 24 of 548 (4.4%) patients with adolescent idiopathic scoliosis, four of 117 (3.4%) patients with juvenile idiopathic scoliosis, 11 of 287 (3.8%) patients with neuromuscular scoliosis, and three of 79 (3.8%) patients with syndromic scoliosis. Infection was the most common indication for complete implant removal [24 (46%) patients], followed by persistent pain [8 (15%) patients], and metal intolerance [8 (15%) patients]. There were two cases of early infection (<1 year following surgery) and 22 late infections (≥1 year following surgery). The overall 22-year incidence of complete implant removal following spinal correction surgery for scoliosis was 4.7%. Infection continues to be the most common indication, followed by pain and metal intolerance.